Teratoma of the testis is a type of mixed tumor made up of various kinds of tissue representing the three primitive layers of blastoderm. Recently we experienced two cases of testicular teratoma in 23-year-old male patients, so we report these two cases of testicular teratoma with review of literatures.
Blastoderm ; Humans ; Male ; Teratoma* ; Testis ; Young Adult

AIMThe production of interspecific germline chimeras between chicken and quail were attempted employing the dissociated cells derived from the blastodermal central disk (stage X) and the germinal crescent region of embryo (stage 7-8).

METHODSThe central disk (CD) of the area pellucida in chicken blastoderm (stage X) and the germinal crescent region (GCR) of embryo (stage 7-8) were dispersed and injected into the subgerminal cavity of quail blastoderm (stage X). Injected eggs were incubated for 7 days or to hatching. The donor chicken DNA was detected by the polymerase chain reaction.

RESULTSIn day-7 embryos, chicken DNA was detected in 5 gonads and 9 brains from 53 survived embryos received chicken CD cells, and 1 gonads and 6 brains from 27 survived embryos received chicken GCR. Chicken DNA was also detected from the semen of one adult male hatched from eggs received chicken GCR cells.

CONCLUSIONCD and GCR cells as the donors showed the possibility to produce the interspecific germline chimera, but further studies are needed to make necessary improvement.

Animals ; Base Sequence ; Blastoderm ; physiology ; ultrastructure ; Brain ; embryology ; Brain Chemistry ; Chick Embryo ; physiology ; Chickens ; Chimera ; DNA Primers ; DNA, Complementary ; genetics ; Embryo, Nonmammalian ; physiology ; Female ; Germ-Line Mutation ; physiology ; Male ; Ovalbumin ; genetics ; Ovary ; embryology ; Polymerase Chain Reaction ; Quail ; Testis ; embryology