Background: Urinary bladder sarcomas are rare in adults, accounting for 0.38-0.64% of bladder tumors. The most recognized treatment for malignant tumors is chemotherapy followed by radiotherapy, but there have been no large scale study to provide a definitive regimen for this condition. Objectives: To determine the outcome of patients with urinary bladder sarcomas. Subjects and method: Between January 2002 and December 2006, 6 patients diagnosed with urinary bladder sarcomas were examined at the Viet Duc Hospital. We retrospectively reviewed the records of these patients for information on clinical features, treatment and outcomes. Results: The mean age of patients was 39.6 years; male/female ratio was 3/1; 66% was leiomyosarcomas, 16.7% was rhabdomyosarcomas, 16.7% was myxosarcomas (n=6). Among these malignant tumors, 3/5 patients were in the advanced stage. Conclusion: Bladder sarcomas were rare in adults. Leiomyosarcomas were more common than rhabdomyosarcomas and had worst outcomes if it is in an advanced stage.
Bladder sarcoma ; Surgery

Inflammatory myofibroblastic tumor of the urinary bladder is a rare mesenchymal tumor with uncertain malignant potential. It often mimics soft tissue sarcomas both clinically and radiologically. Surgical resection in the form of partial cystectomy or transurethral resection remains the mainstay of treatment. Herein we report the case of an inflammatory myofibroblastic tumor in a young girl, which was managed by laparoscopic partial cystectomy. To the best of our knowledge, this is the first reported case of laparoscopic management of an inflammatory myofibroblastic tumor of the urinary bladder.
Cystectomy* ; Granuloma, Plasma Cell ; Laparoscopy ; Myofibroblasts* ; Sarcoma ; Urinary Bladder*

Leiomyosarcoma of the bladder is a very rare tumor and it has been reported in less than 200 cases in the literature which represent 0.1% of all nonurothelial bladder tumors. We experienced a case of sarcoma of bladder that protruding into the urinary bladder in 51-year-old woman. She underwent mass excision with enucleation for the bladder function preservation. Pathologically, the mass consisted of high grade leiomyosarcoma. In immunohistochemical study, tumor showed positive reactions for smooth muscle actin and desmin. After mass excision, follow-up radiation treatment is ongoing. Herein, we present the case of a high-grade leiomyosarcoma with literature review.
Actins ; Desmin ; Female ; Follow-Up Studies ; Humans ; Leiomyosarcoma ; Middle Aged ; Muscle, Smooth ; Sarcoma ; Urinary Bladder Neoplasms ; Urinary Bladder

In the adult, sarcoma of bladder is extremely rare and usually accounts for less than 1 percent of adult bladder tumprs. Leiomyosarcoma, representing a malignancy arising in the smooth muscle cells of the bladder wall, predominates among these rare tumors. Herein a case of leiomyosarcoma of the bladder in a 57-year-old female is presented with a brief of review the literatures.
Adult ; Female ; Humans ; Leiomyosarcoma* ; Middle Aged ; Myocytes, Smooth Muscle ; Sarcoma ; Urinary Bladder*

Rhabdomyosarcomas, malignant neoplasms exhibiting skeletal muscle differentiation, are the most common childhood sarcomas. Embryonal rhabdomyosarcomas of the genitourinary tract also occur in children but are rare in adults. We report a case of embryonal rhabdomyosarcoma arising in the bladder of a 29-year-old man who presented with dysuria and microscopic hematuria. A partial cystectomy was performed, and he received chemotherapy with vincristine and actinomycin.
Adult ; Child ; Cystectomy ; Dactinomycin ; Dysuria ; Hematuria ; Humans ; Muscle, Skeletal ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Embryonal ; Sarcoma ; Urinary Bladder ; Vincristine

Rhabdomyosarcomas, malignant neoplasms exhibiting skeletal muscle differentiation, are the most common childhood sarcomas. Embryonal rhabdomyosarcomas of the genitourinary tract also occur in children but are rare in adults. We report a case of embryonal rhabdomyosarcoma arising in the bladder of a 29-year-old man who presented with dysuria and microscopic hematuria. A partial cystectomy was performed, and he received chemotherapy with vincristine and actinomycin.
Adult ; Child ; Cystectomy ; Dactinomycin ; Dysuria ; Hematuria ; Humans ; Muscle, Skeletal ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Embryonal ; Sarcoma ; Urinary Bladder ; Vincristine

An inflammatory pseudotumor of the urinary bladder might cause a large intraluminal mass that clinically and radiologically simulates a malignant tumor. This benign lesion analogous to nodular fasciitis of soft tissue but occurring in the bladder can easily be mistaken for a sarcoma because by light microscopy it consists of elongated strap cells that resemble rhabdomyoblasts. It is important to recognize this lesion as benign to avoid the potentially serious consequences of misdiagnosis. Herein we report a case of inflammatory pseudotumor of the urinary bladder occurring in a 21-year-old male and review the literatures.
Diagnostic Errors ; Fasciitis ; Granuloma, Plasma Cell* ; Humans ; Male ; Microscopy ; Sarcoma ; Urinary Bladder* ; Young Adult

An inflammatory pseudotumor of the urinary bladder might cause a large intraluminal mass that clinically and radiologically simulates a malignant tumor. This benign lesion analogous to nodular fasciitis of soft tissue but occurring in the bladder can easily be mistaken for a sarcoma because by light microscopy it consists of elongated strap cells that resemble rhabdomyoblasts. It is important to recognize this lesion as benign to avoid the potentially serious consequences of misdiagnosis. Herein we report a case of inflammatory pseudotumor of the urinary bladder occurring in a 21-year-old male and review the literatures.
Diagnostic Errors ; Fasciitis ; Granuloma, Plasma Cell* ; Humans ; Male ; Microscopy ; Sarcoma ; Urinary Bladder* ; Young Adult

Kaposi's sarcoma (KS) is a multifocal hemorrhagic sarcoma that occurs primarily on the extremities. KS limited to the penis is rare and a well-recognized manifestation of acquired immune deficiency syndrome (AIDS). However, KS confined to the penis is extraordinary in human immunodeficiency virus (HIV)-negative patients. We present the case of a 68-year-old man with a dark reddish ulcerated nodule on the penile skin, which was reported as a nodular stage of KS. We detected no evidence of immunosuppression or AIDS or systemic involvements in further evaluations. In his past medical history, the patient had undergone three transurethral resections of bladder tumors due to urothelial cell carcinoma since 2000 and total gastrectomy, splenectomy, and adjuvant fluorouracil/cisplatin chemotherapy for 7 months due to advanced gastric carcinoma in 2005. The patient was circumcised and has had no recurrence for 2 years.
Acquired Immunodeficiency Syndrome ; Aged ; Extremities ; Gastrectomy ; HIV ; HIV Seronegativity ; Humans ; Immunosuppression ; Male ; Penile Neoplasms ; Penis ; Recurrence ; Sarcoma ; Sarcoma, Kaposi ; Skin ; Splenectomy ; Ulcer ; Urinary Bladder Neoplasms

To our knowledge, this is the first report of case of high-grade endometrial stromal sarcoma metastasized to the stomach. Endometrial stromal sarcoma is very rare, accounting for 0.2% of female genital tract malignancies. High-grade endometrial stromal sarcoma demonstrates more frequent infiltration into the muscle layer of the uterus or metastasis to other organs, having a poorer prognosis than low grade disease. During its clinical course, endometrial stromal sarcoma may involve ovary, fallopian tube and pelvic cavity. Distant metastasis to lung, liver, bladder, breast, heart, brain and bones have been reported. However, to the best of our knowledge, high-grade endometrial stromal sarcoma presenting with gastric metastasis has never been reported. We now report a case of a 52-year-old woman with previously diagnosed lung metastasis having stomach metastasis from endometrial stromal sarcoma of the uterus.
Accounting ; Brain ; Breast ; Endometrium ; Fallopian Tubes ; Female ; Heart ; Humans ; Liver ; Lung ; Middle Aged ; Muscles ; Neoplasm Metastasis ; Ovary ; Prognosis ; Sarcoma ; Sarcoma, Endometrial Stromal ; Stomach ; Urinary Bladder ; Uterus