Objective To explore the correlation between family function and clinical symptom in depression and its effect on suicidal ideation.Methods Forms of General information,Hamilton Depression Scales (HAMD),Self-rating Idea of Suicide Scale (S1OSS),Symptom Checklist (SCL-90) and Family Adaptability and Cohesion Scale,Second Edition (FACESII-CV) were used to the survey in which 125 voluntary subjects were involved who were then under the treatment in the hospital.All the subjects were divided into two groups by SIOSS standard for evaluation,including the suicidal ideation group (SIOSS ≥ 12 points;81 cases),and the non-suicidal ideation group (SIOSS ＜ 12 points;44 cases).Results (1) The scores showing FACESII-CV of suicidal ideation patients were evidently lower than those the non-suicidal ideation patients (P ＜ 0.05).The highest proportion of the family type was intermediate type in non-suicidal ideation patients and extreme type in the suicidal ideation patients.(2) The scores showing SCL-90 of suicidal ideation patients were evidently higher than those the non-suicidal ideation patients (P ＜0.05).(3) The scores of family cohesion had negatively correlated with interpersonal sensitivity,hostility,paranoid ideation of SCL-90.The scores of family adaptability had negatively correlated with total scores,total average,positive symptom distresslevel,somatization,obsessive-compulsive,interpersonal sensitivity,depression,anxiety,hostility,paranoid ideation,and psychoticism of SCL-90.The multiple linear regression was Y =2.523X1 (depression)-0.144X2 (family adaptability) + 13.659.Conclusions It is revealed that the suicidal ideation depression patients suffer less sufficient family cohesion and adaptability than non-suicidal ideation.Its clinical symptoms are more complex,diverse,and severe.Most of them have an intermediate type family in non-suicidal ideation depressions,and the most common family type in the suicidal ideation depressions is extreme type family.For the suicidal ideation depression patients,the worse the family function,the more severe the clinical symptoms.Degree of depression and family adaptability has speculated significance to suicidal ideation.

OBJECTIVE: To determine the content of benzhydramine hydrochloride in Xiaoyan Zhentong ointment by RP-HPLC.METHODS: The determination was performed on Zorbax SB-CN column.Acetonitrile-water-triethylamine(51∶49∶0.5,adjusted to pH 6.5 with acetic acid glacial) was used as mobile phase at a flow rate of 1.0 mL?min-1.The detection wavelength was set at 258 nm and the column temperature was set at 30 ℃.RESULTS: The linear range of benzhydramine hydrochloride was 0.1～4.1 ?g(r=0.999 9) with an average recovery rate at 98.4%(RSD=0.44%).CONCLUSION: The method is accurate,sensitive,reliable and applicable for the determination of the content of benzhydramine hydrochloride in Xiaoyan Zhentong ointment.