Objective To describe the status of fatigue and its influencing factors among hypertension patients. Methods A total of 1253 hypertension patients were investigated with global fatigue severity subscale,family APGAR index and self-designed questionnaire. Results 36.7% of hypertension patients were fatigue.Univariate analysis showed that the determinants of fatigue among hypertension patients included older, normal marriage, rural, low educational, mental, family dysfunction (P ＜ 0.05 ). Multivariate analysis revealed that age ( OR =2. 612,95% CI = 2. 047 ～ 3. 333 ), normal marriage ( OR = 1. 754,95% CI = 1. 259 ～ 2. 445 ), manual ( OR =0.810,95 % CI = 0.698 ～ 0.939) and family dysfunction ( OR = 1.717,95 % CI = 1. 396 ～ 2.111 ) were associated with fatigue. Conclusion The rate of status is high in the hypertension patients. The behavior is related to age,marital status, labor type and family function.

Objective:To investigate the post-traumatic stress response in women with unintended pregnancy termination and analyze its related factors.Methods:Totally 388 women with unintended pregnancy termination from two public hospitals in Fujian were selected as the research subjects.They were assessed with the Impact of E-vent Scale-Revised(IES-R),Hospital Anxiety and Depression Scale(HADS),Connor-Davidson Resilience Scale(CD-RISC)and Perinatal Grief Scale(PGS).The total score of IES-R ≥35 was positive for post-traumatic stress disorder screening.Results:The total score of IES-R was(20.6±12.4),and the positive rate of post-traumatic stress disorder screening was 16.5％.Multiple linear regression analysis showed that the IES-R total scores were higher in those who thought pregnancy timing was appropriate than those who thought pregnancy timing was wrong(β=0.13),and lower in women with moderate pain during termination than in those with severe pain(β=-0.09).The IES-R total scores were positively correlated with gestational weeks,depression scores of the HADS and grief scores of the PGS(β=0.18,0.27,0.16),and negatively correlated with optimism scores of the CD-RISC(β=-0.12).Conclusion:The post-traumatic stress response of unintended termination of pregnancy is at a moder-ate level.Post-traumatic stress symptoms are more likely to occur in women who thought pregnancy timing is ap-propriate,and those with severe pain during pregnancy termination,large gestational weeks,high level of depression during pregnancy,and high level of grief after pregnancy termination.

Apoptosis ; Autophagy ; Ferroptosis ; Iron/metabolism* ; Sequestosome-1 Protein/metabolism* ; Ubiquitin-Specific Proteases/metabolism*