No abstract available.
Bioterrorism*

No abstract available.
Bioterrorism*

PURPOSE: This study were designed to supply the opportunity to make a base of emergency syndromic surveillance warning system to detect the bioterrors through the construction of predictive models which were made by reported patients in 'Emergency Syndromic Surveillance System' who were diagnosed as waterborne contagious diseases. METHODS: On this study, we used the neural network analysis methods among the data mining to analyze the reliable variables which was extracted from the reported data bases in the Emergency Syndrome Surveillance System. RESULTS : In this study, we were using the patients data pools from 13th May 2002 to 13th May 2003 in Emergency Syndrome Surveillance System. So we could get the reliable variables - clinical symptoms, severity of patient, humidity and temperature - to predict the waterborne infections. This study shows the successful predictation rate of 96% in error rate of 0.4 with sensible variables through Chisquare analysis and the construction of one hidden layer which is near linearity. CONCLUSION: Early emergency syndromic surveillance warning models made by the neural network in Emergency Syndrome Surveillance System could make the early detection of waterborne infections, could also stop the transmission of waterborne infections in early stage, and furthermore could be used as the preventive and detective methods of bioterror attacks.
Bioterrorism ; Data Mining ; Emergencies* ; Humans ; Humidity

The study was conducted between 1/2004 and 6/2005 in civilian-military health care commitees at 61provinces and cities and in civilian-military health care facilities. Aims of this study is to analyse the basic issues of civilian-military health care combination in preventive health and response to epidemics and disasters. The study also produced some recommendations on the model of mobile civillian - military medical team in prevention dangerous epidermics and bioterrorisms
Bioterrorism ; Preventive Health Services ; Military Personnel

The Laboratories engaging with microorganisms have some potential risks, depending on handling of pathogens. The safety management system to extend recognition of biosafety and biosecurity needs to be established and practiced in order to prevent hazard possibility and secure safety of researchers who deal with pathogen. As the importance and regulation of global biosafety and biosecurity tended to be intensified, various laws and institutions for the security of biosafety were established when the Act on implementation of Living Modified Organisms, an implantation act of Cartagena was enforced in Korea in 2008. In particular, the system of permission report for Living Modified Organism (LMO), Highly Dangerous Pathogens (HDPs) and Biological Weapons Convention (BWC), in order to prevent intended or non-intended leakage and occurrence of biohazard derived from pathogen and infectious substance and safely use them. The bioterrorism can be controlled and autonomous management of biosafety by agencies that handle pathogens can be also secured by practicing the various laws and institutions.
Biological Warfare Agents ; Bioterrorism ; Jurisprudence ; Korea ; Safety Management

PURPOSE: This study reviewed the development of and analyzed the early results from syndromic surveillance based on emergency departments, which was developed to detect bioterrorism attacks, especially during the 2002 FIFA Korea-Japan World Cup games. METHOD: Data from homepages and server computers were analyzed from May 13 2002, to August 5 2002. The data were gathered everyday from 121 emergency departments in Korea via the internet by using PC or PDA. Some data gathered via telephone or FAX were also digitalized. RESULTS: The daily report rate was 82.5% on average. Most of the cases were acute respiratory syndrome (63.4%) and acute sporadic diarrheal syndrome (34.8%). No bioterrorism was confirmed during this period. The peak times and distributions of sporadic and cluster cases of acute diarrheal syndrome are not equivalent. In the case of level 2 reports, there was an average of 12 cases per one institute and 32.8 cases per institute of level 1 and 2 reports totally. CONCLUSIONS: The emergency department syndromic surveillance system for bioterrorism is the first everyday reporting system based on the clinical basis in emergency depart-ments. It has been and is functioning without large problems, but exact knowledge of and more participation by reporting institutes are required. It is necessary to survey the results for a longer period and to correct the early problems if we want to know the ultimate usefulness of this system.
Academies and Institutes ; Bioterrorism* ; Emergencies* ; Emergency Service, Hospital* ; Internet ; Korea ; Telephone

OBJECTIVES: The aim of this study was to estimate the medical surge capacity required for mass prophylaxis based on a hypothetical outbreak of smallpox.METHODS: We performed a simulation using the Bioterrorism and Epidemic Outbreak Response Model and varied some important parameters, such as the number of core medical personnel and the number of dispensing clinics.RESULTS: Gaps were identified in the medical surge capacity of the Korean government, especially in the number of medical personnel who could respond to the need for mass prophylaxis against smallpox.CONCLUSIONS: The Korean government will need to train 1,000 or more medical personnel for such an event, and will need to prepare many more dispensing centers than are currently available.
Bioterrorism ; Korea ; Smallpox ; Surge Capacity ; Vaccination ; Variola virus

Tularemia is a high-risk infectious disease caused by Gram-negative bacterium Francisella tularensis. Due to its high fatality at very low colony-forming units (less than 10), F. tularensis is considered as a powerful potential bioterrorism agent. Vaccine could be the most efficient way to prevent the citizen from infection of F. tularensis when the bioterrorism happens, but officially approved vaccine with both efficacy and safety is not developed yet. Research for the development of tularemia vaccine has been focusing on the live attenuated vaccine strain (LVS) for long history, still there are no LVS confirmed for the safety which should be an essential factor for general vaccination program. Furthermore the LVS did not show protection efficacy against high-risk subspecies tularensis (type A) as high as the level against subspecies holarctica (type B) in human. Though the subunit or recombinant vaccine candidates have been considered for better safety, any results did not show better prevention efficacy than the LVS candidate against F. tularensis infection. Currently there are some more trials to develop vaccine using mutant strains or nonpathogenic F. novicida strain, but it did not reveal effective candidates overwhelming the LVS either. Difference in the protection efficacy of LVS against type A strain in human and the low level protection of many subunit or recombinant vaccine candidates lead the scientists to consider the live vaccine development using type A strain could be ultimate answer for the tularemia vaccine development.
Bioterrorism ; Communicable Diseases ; Francisella tularensis ; Humans ; Sprains and Strains ; Stem Cells ; Tularemia ; Vaccination ; Vaccines

Bioterrorism ; classification ; psychology ; trends ; Communicable Diseases ; transmission ; Disease Transmission, Infectious ; prevention & control ; Humans

Since bioterrorism has become reality after its occurrence in USA, our goverment is preparing and conducting strategic plans for preparedness and response to bioterrorism. The major plans consist of reinforcement of surveillance of notifiable communicable diseases, construction of supplementary surveillance systems, organization of emergency department and infection specialists networks, strengthening of laboratory capacity and network, and establishment of a stepwise response plan according to risk assessment. For the preparedness for bioterrorism, we are preparing a national pharamaceutical stockpile (antibiotics, smallpox vaccine, etc) and strengthening the organization, law, epidemiologic capacity, research, and management of critical infectious agents. It is very difficult to predict the risk of bioterrorism, which may be very low. Nevertheless, the complete preparedness is necessary to prevent social confusion by bioterrorism. Especially, phisician's role in response to bioterrorism such as case detection, report, management, and treatment is very important.
Bioterrorism* ; Communicable Diseases ; Emergency Service, Hospital ; Jurisprudence ; Risk Assessment ; Smallpox Vaccine ; Specialization