1.Biotechnology in Viet Nam
Journal of Medical Research 2005;36(3):77-83
Medical biotechnology is technical solutions using biological properties of cells and of biological moleculars for diagnosis, treatment and prophylaxis. Considerable achievements were gained in Vietnam despite it was applied lately and the investment in medical biotechnology is lower. These achievements include early detection and diagnosis of genes causing cancers like throat-nose cancer, liver cancer, some bacterial and viral infections, some hereditary diseases, bio-products for treatment like anti-rabies serum, anti-venom serum, and vaccines for diphtheria, pertussis, tentanus, hepatitis B, hepatitis A (Havax), Japanese encephalitis, polio and typhoid.
Biotechnology Vietnam
2.Development and perspective of bio-based chemical fiber industry.
Chinese Journal of Biotechnology 2016;32(6):775-785
Bio-based fiber is environment friendly, reproducible, easily biodegradable. Therefore, rapid development of bio-based fiber industry is an obvious in progress to replace petrochemical resources, develop sustainable economy, build resource saving and environment friendly society. This article describes the current development of bio-based fiber industry, analyzes existing problems, indicates the trends and objectives of bio-based fiber materials technology innovation and recommends developing bio-based fibers industry of our country.
Biotechnology
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Chemical Industry
3.Preface for special issue on industrial biology (2019).
Chinese Journal of Biotechnology 2019;35(10):1801-1805
Industrial biotechnology promises to make a significant contribution in enabling the sustainable development, and need the solid support from its basic discipline. As the basis of industrial biotechnology, industrial biology is to study the basic laws and mechanisms of biological behavior in industrial environment and to solve the key scientific problems for understanding, designing and constructing the organisms adapted to the application of industrial environment. In order to comprehend the status of industrial biology, we published this special issue to review the progress and trends of industrial biology from the three aspects of industrial protein science, cell science and fermentation science, respectively, for laying the foundation for the development of industrial biotechnology.
Biotechnology
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Fermentation
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Industrial Microbiology
4.Engineering and process management-based design of Comprehensive Biotechnology Experiment course.
Changbin GONG ; Fei CAO ; Honghua JIA ; Kequan CHEN ; Ganlu LI ; Bingfang HE
Chinese Journal of Biotechnology 2023;39(2):769-779
Based on the demand of enterprise talents and the characteristics of manufacturing process management in biotechnology, in order to make the students acquire the ability to solve complex engineering problems in the production process, we developed a "Comprehensive Biotechnology Experiment" course, where two-step enzymatic production of l-aspartate and l-alanine were the key processes. In this course, we drew lessons from the site management of the production enterprise, performed the experimental operation mode of four shifts and three operations. The content of this course includes principles, methods and experimental techniques of several core curricula and the site management mode of enterprises. As to the evaluation, the summary of the experimental staff's handover records and the content of teamwork were examined and scored. Through teaching practice and continuous improvement, we developed a complete experimental teaching process and assessment mechanism. Overall, the Comprehensive Biotechnology Experiment course achieved good teaching effect, which may serve as a reference to promote the development of experimental teaching of biotechnology.
Humans
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Biotechnology
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Curriculum
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Students
5.Reform and practical experience of bilingual course for "Environmental Biotechnology" with the development of "Emerging Engineering Education".
Chinese Journal of Biotechnology 2021;37(12):4475-4481
The construction of "Emerging Engineering Education" aims at cultivating high-quality graduates capable of engineering practice, innovation and international competitiveness. Bilingual courses have become one of the effective means to cultivate qualified students with skills of both professional knowledge and international communication. However, the teaching effect of most bilingual courses is not very ideal. Based on analyzing common problems in the current bilingual teaching, we take the bilingual course of environmental biotechnology as an example, and discusses possible improvement strategies from the aspects of the construction of teaching mode, the establishment of quality control system, the selection of textbooks and the optimization of assessment methods. Moreover, we summarize experience and shortcomings on improving the lecturers' ability, students' learning enthusiasm and school's support. It is expected to provide useful reference for improving the effect of bilingual teaching in biotechnology-relevant courses.
Biotechnology
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Curriculum
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Humans
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Students
6.Practice in fostering postgraduates' creativity through teaching the course of Modern Microbial Biotechnology.
Chinese Journal of Biotechnology 2021;37(4):1450-1456
Improving the creativity is crucial to postgraduate training nowadays. The course of Modern Microbial Biotechnology is an optional specialized course for microbiology-related postgraduates. To explore a new teaching mode for improving the creativity of postgraduate students, we reformed the teaching content, the teaching method and the evaluation mode of this course. Through case study teaching, seminar-style classroom and implementation of a new assessment method, the students not only mastered professional knowledge and disciplinary frontiers of modern microbiology technology, but also improved their ability of discovering, analyzing and solving problems. The reformed course teaching mode is effective in fostering postgraduates' creativity.
Biotechnology
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Humans
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Students
7.Clinical trials and ethics.
Journal of the Korean Medical Association 2010;53(9):774-779
Based on recently developed biotechnology, many new drugs have been developed for improving patient treatment outcomes. To develop novel drugs, proper clinical trials are essential. As clinical trials involve humans in research, the protection of participants is important not only for the participants' safety but also for future patients. Ethics in a clinical trial is not the same as in clinical practice with enough evidence. Hence, the whole procedure of a clinical trial should be well organized, scientifically and ethically planned, and monitored properly by an Institutional Review Board (IRB). Here the importance of ethics in clinical trials, related issues, and the monitoring system will be discussed.
Biotechnology
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Ethics Committees, Research
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Humans
8.Progress on polyhydroxyalkanoates (PHA).
Jin YIN ; Xuemei CHE ; Guoqiang CHEN
Chinese Journal of Biotechnology 2016;32(6):726-737
Microbial polyhydroxyalkanoates (PHA) has developed with more diversity and more advanced manufacturing technology. Diversity has now been reflected by diverse monomers, diverse structures and diverse polymerization modes, giving the concept of "PHAome". In addition, the application of synthetic biology and the development of seawater-based biotechnology reduce the production cost of PHA, making PHA more economically competitive. Some examples of commercialized PHA products are described here. Besides, PHA with high value added applications has been exploited.
Biotechnology
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Polyhydroxyalkanoates
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chemistry
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Synthetic Biology
10.Progress in intelligent control of industrial bioprocess.
Xiwei TIAN ; Guan WANG ; Siliang ZHANG ; Yingping ZHUANG
Chinese Journal of Biotechnology 2019;35(10):2014-2024
Industrial bioprocess is a complex systematic process and bio-manufacturing can be realized on the basis of understanding the metabolism process of living cells. In this article, the multi-scale optimization principle and practice of industrial fermentation process are reviewed, including multi-scale optimizing theory and equipment, on-line sensing technology for cellular macroscopic metabolism, and correlated analysis of physiological parameters. Furthermore, intelligent control of industrial bioprocess is further addressed, in terms of new sensing technology for intracellular physiological metabolism, big database establishment and data depth calculation, intelligent decision.
Bioreactors
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Biotechnology
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Fermentation
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Industrial Microbiology