1.Biologic therapies in Crohn's disease.
Korean Journal of Medicine 2005;68(2):133-139
No abstract available.
Biological Therapy*
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Crohn Disease*
3.Eligibility of C-BIOPRED severe asthma cohort for type-2 biologic therapies.
Zhenan DENG ; Meiling JIN ; Changxing OU ; Wei JIANG ; Jianping ZHAO ; Xiaoxia LIU ; Shenghua SUN ; Huaping TANG ; Bei HE ; Shaoxi CAI ; Ping CHEN ; Penghui WU ; Yujing LIU ; Jian KANG ; Yunhui ZHANG ; Mao HUANG ; Jinfu XU ; Kewu HUANG ; Qiang LI ; Xiangyan ZHANG ; Xiuhua FU ; Changzheng WANG ; Huahao SHEN ; Lei ZHU ; Guochao SHI ; Zhongmin QIU ; Zhongguang WEN ; Xiaoyang WEI ; Wei GU ; Chunhua WEI ; Guangfa WANG ; Ping CHEN ; Lixin XIE ; Jiangtao LIN ; Yuling TANG ; Zhihai HAN ; Kian Fan CHUNG ; Qingling ZHANG ; Nanshan ZHONG
Chinese Medical Journal 2023;136(2):230-232
5.Co-evolutionary analysis on strategy for therapy of spreading cancer.
Ke-Fu WU ; Guo-Guang ZHENG ; Xiao-Tong MA ; Xiao-Fan ZHU ; Ye GUO ; Yu-Hua SONG
Journal of Experimental Hematology 2012;20(3):523-526
Evolutionary medicine can give rational explanation for metabolism diseases via ecology and evolutionary theory. Recently, the view of somatic cell macroevolution was used in the study on the genesis and development of tumors, which provided new insight in the research work on tumors. In this article, the well-adopted tumor therapy strategy, "Dancing with Cancer", was analyzed preliminarily from the point of co-evolution game theory, based on the non-classical immunology theory and genome theory. The importance of increasing host fitness by changing host life-style to enhance tolerance was emphasized, which is the basis of the Dancing with Cancer strategy. On the other hand, the spreading tumor cells are not equally malignant and spreading tumors should be treated as other chronic diseases. Finally, basic and clinical research should be strengthened to improve the efficiency of the "Dancing with Cancer" strategy.
Biological Evolution
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Game Theory
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Neoplasms
;
therapy
6.Contribution to the study on some biological properties of flavonoids in leaves of Carica papaya L
Pharmaceutical Journal 2001;305(9):15-17
The flavonoids from papaya leaves have the selective action on the cells. It destroyed cancer cells Hep-2, but don't make any bad influence to the normal lymphocyte. In addition, The obtained flavonoids have mitogenic activity on the lymphocyte of human. Flavonoids of papaya leaves have different effect on the inhibition of the growth and development of bacteria
Biological Therapy
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flavonoids
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microbiology
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Plants, Medicinal
7.Study on manufacturing method and some biological properties of the drug Monkshood Root in Sapa region
Pharmaceutical Journal 2003;322(2):21-24
A study for processing Radix Aconiti carmichaelii in Sapa (Lao Cai province) by traditional method. Radix Aconiti was immersed in sodium and magnesium chloride solutions for 12 to 14 days until having or without slightly pungent and numb taste. Studying the chemical ingredients showed that the content of total alcaloids and aconitin were reduced. Radix Aconiti processed in different ways had different action of cardiotonic. Studying acute toxicity found that no death of mice with oral maximum dose of 320g radix aconiti per kg body weight of animals
Biological Therapy
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Pharmaceutical Preparations
;
Medicine, Traditional
;
drugs
9.Progress of biotherapy in gastrointestinal carcinomas.
Jian-chuan XIA ; De-sheng WENG
Chinese Journal of Gastrointestinal Surgery 2013;16(1):22-27
Gastrointestinal carcinomas are among the malignancies with highest morbidity and mortality. The survival rates of these tumors remain pretty low in spite of advancements of traditional treatments. As the fourth treatment method besides surgery, radiotherapy and chemotherapy, biotherapy has shown promising prospect in improving the prognosis of gastrointestinal carcinomas. In this manuscript, we summarized the current progress of biotherapy in gastrointestinal tumors including gene therapy, immune therapy and molecular targeted therapy.
Biological Therapy
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Gastrointestinal Neoplasms
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therapy
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Genetic Therapy
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Humans
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Immunotherapy
10.Developmental Strategy for Stem Cell Therapy Products in Regulatory Considerations.
In Young CHANG ; Kyung Suk KIM
Hanyang Medical Reviews 2012;32(3):163-169
Expectation that stem cell therapy products will prove better and more effective in treating a variety of medical conditions continues to drive expanding research efforts. Stem cell therapy products consist of, or are derived from, populations of stem cell progenitors. They are complex and dynamic biological therapies which are highly regulated for safety and efficacy as biological products. The Korea Food Drug Administration (KFDA) is the legal authority responsible to regulate stem cell therapy products as stipulated by the Pharmaceutical Affairs Act. In this article, the regulatory review process used by the KFDA to assess the safety and effectiveness of novel stem-cell therapy products is described. The agency regularly updates and re-evaluates recommendations applicable to production and testing of stem cell therapy products based on the accumulation of scientific and clinical experiences.
Biological Agents
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Biological Therapy
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Informed Consent By Minors
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Korea
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Stem Cells
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Treatment Outcome