OBJECTIVE: To realize the risk factors, clinical features, and treatments of Staphylococcal scalded skin syndrome (SSSS).
 METHODS: The clinical features, laboratory findings, and treatment were retrospectively analyzed in 290 patients from Hunan Children's Hospital.
 RESULTS: Of the 290 patients, less than 3 years old children were 76.6%. One hundred and nine patients had induced factors, and 177 patients had elevated white blood cell count. There were 168 patients with SSSS accompanied with fever, 34 patients accompanied with diarrhea, and 58 patients associated with septicemia. Eighty-five patients performed the bacterial cultures of the skin secretions, 21 did the throat swab, and 13 did both of the skin secretions and throat swab. Bacterial culture results showed that 119 samples were positive for Staphylococci. All patients were cured after antimicrobial therapy. The skin lesions were improved in 3.26 d. The mean hospital stay was 6.55 d. Recovery time of the body temperature was 3.48 d in average.
 CONCLUSION SSSS predominates in infants and children under 3 years old, and has tendency to combine with multi-organ symptoms. The early diagnosis and active antimicrobial treatment are the keys of successful treatments.
Anti-Bacterial Agents ; therapeutic use ; Child, Preschool ; China ; Humans ; Infant ; Length of Stay ; Retrospective Studies ; Risk Factors ; Sepsis ; Skin ; microbiology ; Staphylococcal Scalded Skin Syndrome ; diagnosis ; drug therapy ; pathology