OBJECTIVE:To enhance the quality control in the course of therapeutic drug monitoring(TDM).METHODS:The prospective and retrospective quality control were performed on application,sampling,detection and data processing,in?cluding within-ward and neighboring ward quality control.RESULTS:The work norm of quality control was estab?lished.CONCLUSION:Great emphasis ought to be given to quality control since it plays a decisive role in improving the ac?curacy and precision of TDM result.