1.The clinical effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the X-ray radiotherapy-induced lung injury
Xiaomin ZHANG ; Bingsheng WANG ; Yanli GE ; Jianyu ZHANG
Clinical Medicine of China 2011;27(9):908-910
ObjectiveTo observe the effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the treatment of the X-ray radiotherapy-induced lung injury.MethodsEighty-four patients who were given three-dimensional conformal radiotherapy were randomized into treatment group and control group.The patients in treatment group were given traditional Chinese medicine, which supplements Qi and activates blood circulation, while the patients in control group were given antibiotics and hormone instead.ResultsThe outcome of treatment group was better than that of control.The response rates were 88.6% and 60.0%, respectively (x2 = 9.16, P < 0.05) .Compared with the patients in control group, the clinical manifestations and pulmonary CT reflected better response in the patients of the treatment group(x2 =12.22,P < 0.05) .ConclusionThe traditional Chinese medicine, which supplements Qi and activates blood circulation,has a good therapeutical effect on radiation pneumonitis and protective role for radiation-induced pulmonary fibrosis.
2.Tracheal carinal reconstruction and bronchovasculoplasty in central type bronchogenic carcinoma.
Deruo LIU ; Yongqing GUO ; Bin SHI ; Yanchu TIAN ; Zhiyi SONG ; Qianli MA ; Zhenrong ZHANG ; Bingsheng GE
Chinese Journal of Lung Cancer 2010;13(4):352-356
BACKGROUND AND OBJECTIVEBecause radical resection for lung cancer invading the initial borderline of different lobes and carina is difficult, we tried to analyse the variables of successful tracheal carinoplasty and bronchovasculoplasty to discover a proper approach for appropriate early and long-term results.
METHODSOf 1 399 lung resections for primary lung cancer performed in our hospital from April 1985 to December 2006, 133 underwent bronchoplastic surgeries, including 15 carinoplasty cases and 118 sleeve lobectomy (SL) cases, and 118 pneumoectomy (PN) cases were compared at the same time.
RESULTSComplications occurred in 18 cases, with no operative related mortality. For all patients, the 1 year, 3 year, and 5 year survival rates were 79.8%, 56.7% and 31.2%, respectively. The 5 year survival rate by cancer stage was 69.2% for Ib, 40.6% for IIb, 19.6% for IIIa, and 16.6% for IIIa (N2).
CONCLUSIONSelection of cases, clearance of lymph nodes, disposal of the bronchus and pulmonary vessel and replacement or restoration of the superior vena cava are the main factors influencing prognosis.
Adult ; Aged ; Carcinoma, Bronchogenic ; mortality ; surgery ; Female ; Humans ; Lung Neoplasms ; mortality ; surgery ; Lymphatic Metastasis ; Male ; Middle Aged ; Survival Rate ; Trachea ; pathology ; surgery ; Treatment Outcome
3.Allogeneic single lung transplantation in 7 cases
Deruo LIU ; Yongqing GUO ; Fengrui ZHAO ; Futian LI ; Bingsheng GE ; Bin SHI ; Yanchu TIAN ; Zhiyi SONG ; Yanning SHOU ; Haitao ZHANG ; Chaoyang LIANG ; Zaiyong WANG ; Jingyu CHEN ; Tong BAO ; Zhenrong ZHANG ; Yuling XIN
Chinese Journal of Tissue Engineering Research 2008;12(53):10567-10570
The present case report was designed to summarize the clinical experience of operative technique. lung preservation, lung perfusion, and perioperative management. Of 7 cases who underwent allogenic single lung transplantation (LT), 3 were idiopathic pulmonary fibrosis, 2 were chronic obstructive pulmonary disease, 1 was silicosis, emphysema, and bulla, and I was tuberculosis in both sides and presented with destroyed lung in one side. All donors were already brain death. Donor lungs were well preserved utilizing Euro-Colins liquid or low-potassium dextran solution. Donors and recipients were matched in blood type. Of 7 cases selected,5 received single right lung transplantation, and 2 received single left LT. End-to-end anastomosis was performed for pulmonary branches and pulmonary arteries. while atrium-to-atrium anastomosis was performed for pulmonary vein. Antibiotics and immunosuppressants were routinely used prior to and subsequent to LT. Following LT, heart and lung function, usage of antibiotics, and adjustment of immunosuppressant were monitored. Stomal complications regarding bronchus and pulmonary artery and vein did not appear in any patient. Five cases survived for about 2 months, one for approximately 1 year, and one for nearly 2 years. Four cases died of multi-organ failure caused by pulmonary infection, and one of severe pulmonary hemorrhage caused by aspergillus sydowi infection. Rejection occurred in 6 cases. One case sufiered from rejection three times. Selection of indication, selection and preservafton of donor lung, LT operation and pre-and post-operative management of LT have acquired satisfactory achievements. High mortality occurred in patients with preoperative poor cardiac and pulmonary functions and postoperative severe infections accompany with application of immunosuppressant.
4.Late-stage emphysema treated with lung volume reduction: report of 22 cases.
Fengrui ZHAO ; Deruo LIU ; Bin SHI ; Yanchu TIAN ; Zaiyong WANG ; Tong BAO ; Futian LI ; Yongqing GUO ; Haitao ZHANG ; Jingyu CHEN ; Bingsheng GE
Chinese Journal of Surgery 2002;40(3):194-197
OBJECTIVETo Summarize the clinical experience in the treatment of late-stage emphysema by lung volume reduction (LVR) in 5 years.
METHODSWe retrospectively studied the indications, contraindications, operation procedures and complications of LVR in 22 patients.
RESULTSBefore operation, the average FEV(1) was 24.5%, RV 196.8%, and TLC 130.5%; after operation they were 27.8%, 148.8% and 112.5%, respectively. 16 patients needed inhaling oxygen before operation, and 5 after operation. 16 patients finished 6-minute walking test with an average of 198 m, all patients walked much longer with an average of 256 m after operation. 3-degree lung function was observed in 14 patients, and 4-degree before operation in 8 patients; but 2-degree lung function in 5 patients, 3-degree in 13, and 4-degree in 4 after operation.
CONCLUSIONSHeterogeneous type emphysema with clear target area, especially bullous emphysema is the best indication for LVR. Lung function and life quality could be much improved postoperatively. Homogeneous type could also be treated with LVR in highly selected cases. TLCO < 20% is not an absolute contraindication, others standards need further investigation. Video-assistant thoracoscopic surgery (VATS) with subaxillary small incision for LVR is safe, reliable and effective. Application of stapler buttressing with bovine pericardia could decrease air leakage postoperatively.
Aged ; Female ; Humans ; Male ; Middle Aged ; Pneumonectomy ; Pulmonary Emphysema ; surgery ; Retrospective Studies ; Thoracoscopy