The paper was a study on the effect of UBIO on ischemic strokes. 80 Cases with acute ischemic strokes were randomly divided into two groups:UBIO group and control group. Clinic effectiveness,hemorheology and in vitro infarction were studied before and after 14 days treatment. Clinical results showed that the excellent,effetive rate of UBIO group was respectively better than that of control group (P<0.05). The results of hemorheology and in vitro infarction showed UBIO has a faster effectiveness than control group. The results indicate that UBIO therapy is a hopeful assistant method for the treatment of acute ischemic strokes.