1.Characterization of anticoagulant biomaterial and its development.
Bingcan CHEN ; Danqun HUO ; Jiajia RAO ; Changjun HOU ; Mingyuan LI
Journal of Biomedical Engineering 2005;22(2):428-432
Good anticoagulant biomaterials need good surface chemical properties, good mechanics performances and particularly good characteristics of biocompatibility, including tissue compatibility and hemocompatibility. In order to understand with greater clearness the anticoagulant biomaterial, we have to characterize them by different methods. In this paper, the approaches to assessing and displaying the characteristics of anticoagulant biomaterial are reviewed in three aspects, namely the surface chemical properties and structure, the mechanics performances the and the biocompatibility of anticoagulant biomaterial.
Anticoagulants
;
Biocompatible Materials
;
chemistry
;
Blood Coagulation
;
drug effects
;
Humans
;
Materials Testing
;
Prostheses and Implants
;
adverse effects
;
Prosthesis Design
;
Surface Properties
2.Study on all-round evaluation of biocompatibility of biomaterial.
Danqun HUO ; Dongni ZHAN ; Changjun HOU ; Wenbing ZHANG ; Shujia ZHENG ; Yanrong REN ; Bingcan CHEN
Journal of Biomedical Engineering 2006;23(6):1350-1354
Biocompatibility has always been the focal point in the study of biomaterials applied to medical apparatus. But at present, the standard system hasn't formed completely to evaluate the biomaterials. In recent years scientists tend to use general standard of evaluation. In this article, based on the recalcification time, the adhesion of platelets as well as the total quantity of plasma protein and some other evidences, combining with the Analytic hierarchy process (AHP), the method of general evaluation on the biocompatibility of anticoagulant biomaterials was discussed.
Anticoagulants
;
analysis
;
Biocompatible Materials
;
standards
;
Blood Proteins
;
analysis
;
Humans
;
Materials Testing
;
methods
;
standards
;
Platelet Adhesiveness
;
drug effects