ObjectiveTo investigate the method of nursing care in craniopharyngioma by analyzing the common post-complications after microsurgical treatment of craniopharyngioma. MethodsThe nursing care data of pituitary adenoma after microsurgical treatment in 77 patients were analyzed retrospectively. ResultsThere are 10 cases occurring with the complication in 77 cases. After active treatment, the complications were rectified in most cases.ConclusionEarly detection and correct treatment of complications were the key of post-operative care, mortality and morbidity can be reduced effectively.

There are 32 academic libraries in Guangdong Province.Of the 16 academic libraries with their Wechat public account opened, 11 provide historical news push service.The frequency, contents and interaction of historical news push service in these 11 academic libraries were analyzed, which showed that no importance was attached to Wechat service and Wechat service was not sufficiently developed, the Wechat public account did not play its role, the Wechat contents were simplistic, and the interaction between Wechat public platforms of libraries and users was insufficient in 50%academic libraries of Guangdong Province.Certain suggestion were thus put forward for their solutions, such as standardizing Wechat public account, popularizing Wechat public account, positioning Wechat service, enforcing active Wechat information push, innovating Wechat information service, enriching Wechat form, and perfecting Wechat self service function.

COVID-19 caused by SARS-CoV-2 infection poses a great threat to the lives of people around the world and has become a major global public health challenge. The innate immune system is the body's first line of defense against viral invasion and plays an important role in the development of COVID-19. As the main immune cells in the innate immune system, monocyte macrophages have pattern recognition receptors on their surface that recognize SARS-CoV-2 singlestranded RNA and damage associated molecular patterns(DAMPs) and induce antiviral innate immune responses. However,SARS-CoV-2 has a strong immune escape ability and can rapidly expand and replicate in host cells and induce host cell death, which further induces an inflammatory response and exacerbates COVID-19. Studies have shown that macrophage infiltration-induced hyperinflammatory responses(i.e., cytokine storms) are an important lethal mechanism of COVID-19,and that during SARS-CoV-2 infection, the over-activation of glycolysis is an important metabolic mechanism for viral immune escape and inflammatory response. This paper reviews the related research progress of glucose metabolism in the innate immune response against SARS-CoV-2.

Emotional illness spread in every clinical system disease, contained very complex sub-illness. At present, though there were plenty of clinical reports on emotional illness, few reports were substantive. Therefore, this paper put forward to establish a standard emotional diagnosis system by inheriting the traditional four diagnostic methods and absorbing the diagnostic techniques of modern psychosomatic medicine;according to the specific circumstances of emotional illness, the individual simultaneous treatment or separate treatment of mind and physique was used to establish a standardized system for treating emotional illness

Objective To investigate the effect of dichloroacetate on the expression of Kv1.5 in a rat model of pulmonary arterial hypertension (PAH) .Methods Thirty-two male SD rats weighing 200-250 g were randomly divided into 4 groups ( n = 8 each): normal control group (group C), dichloroacetate control group (group D),PAH group, and PAH + dichloroacetate group (group PD). PAH was induced by left lung resection combined with subcutaneous injection of monocrotaline 60 mg/kg in PAH and PD groups. In group PD, dichloroacetate 80 mg/kg was given through a gastric tube into stomach once a day for 28 consecutive days after monocrotaline injection,while the equal volume of normal saline was given instead of dichloroacetate in group PAH. Group D only received dichloroacetate 80 mg/kg through a gastric tube into stomach once a day for 28 consecutive days. Pulmonary arterial pressure (PAP) was measured at day 28 after monocrotaline injection. The rats were then sacrificed and lung tissues were removed to calculate the percentage of thickness of the tunica media of pulmonary artery and right venicular hypertrophy index and to determine the proliferating cell nuclear antigen (PCNA) and Kv1.5 protein expression (by Western blot) and Kv1.5 mRNA expression (by RT-PCR).Results Compared with group C, the PAP,percentage of thickness of the tunica media, right ventricular hypertrophy index were significantly increased, Kv1.5 mRNA and protein expression was down-regulated and PCNA expression was up-regulated in groups PAH and PD ( P ＜ 0.05). Compared with group PAH, the PAP, percentage of thickness of the tunica media, right ventricular hypertrophy index were significantly decreased, Kv1.5 mRNA and protein expression was up-regulated and PCNA expression was down-regulated in group PD (P ＜ 0.05). There was no significant difference in the indexes mentioned above between group C and group D ( P ＞ 0.05). Conclusion Dichloroacetat alleviates PAH through upregulating Kv1.5 expression in lung tissues and inhibiting pulmonary vascular remodeling in rats.

Objective To explore the effect of Buzhong Yiqi combined with low frequency impact feedback and rehabilitation training on postpartum pelvic floor rehabilitation.Methods100 cases of maternal fertility were randomly divided into observation group and control group, and 50 cases were randomly divided into observation group and control group.The control group was given low-frequency shock and electrical stimulation and rehabilitation training intervention, the observation group in the control group at the same time plus the addition of Buzhong Yiqi Tang treatment, were treated for 3 months.To evaluate and compare the pelvic floor muscle function, vaginal tension, vaginal pressure and nocturia before and after treatment, and compare the quality of life and the occurrence of complications after treatment.ResultsThere were no significant differences in the parameters of the pelvic floor muscle, vaginal tension, vaginal pressure and nocturia before treatment.and the maximal muscle voltage of the pelvic floor muscle and the pelvic floor muscle contraction were 60 s, the mean muscle voltage values of the pelvic floor muscle were significantly increased (P<0.05).However, the vaginal muscle tension and vaginal pressure in the observation group were significantly higher than those in the control group (P<0.05), and the vaginal muscle tension and vaginal pressure were significantly higher (P<0.05), but the number of nocturia in the observation group was significantly lower than that in the control group (P<0.05), and the FS-FI score of the observation group was significantly higher than that of the control group (P<0.05).The incidence of urinary incontinence was 4.26% and 6.38% in the observation group were significantly lower than those in the control group (16.67%, 18.75%, P<0.05).ConclusionBuzhong Yiqi Fang combined with low-frequency shock and electric stimulation, rehabilitation training treatment is conducive to promoting maternal postpartum pelvic floor rehabilitation, improve sexual quality of life, and can effectively reduce the incidence of pelvic organ prolapse, urinary incontinence.

1263 children aged 3-6 years old in Wuxi city were included.Overweight 191 children were overweighte,104 obese and 968normal.SPSS analysis showed that deciduous teeth caries and age were positively relative (F=31.77,P=0.0001);obesity and age were not relative(x2 =36.00,P=0.33);deciduous teeth caries and obesity were not relative (F =0.21,P =0.808).Deciduous teeth caries is not related with obesity.

This is to retrospectively review and summarize the ultrasonic images of 214 patients who were diagnosed as clonorchiasis and received treatment. The major changes in ultrasonography were found in gallbladder and hepatic bile duct. Flocculent echos in the gallbladder were the characteristic feature,which disappeared after chemotherapy. The wall of hepatic bile duct became thicker and shaggy in most patients. These changes improved quite slowly after treatment. Ultra-sonography is of value in the diagnosis of clonorchiasis sinensis

Natriuretic factors,include cardionatrin(CN)and digoxin-like immunoreac-tive substances(DLIS),were important humoral factors relating to ascites formation inliver cirrhosis.An observation was made on the levels of plasma CN,DLIS,angiotensinⅡ, aldosterone and serum and urine sodium contents berore and after ascites extinction in40 cirrhotic patients.The results showed that the plasma levels of CN and DLIS had dis-tinct changes before and after ascites extinction and their changes were parallel with theactivity of renin-angiotensin-aldosterone system.These facts suggested that CN and DLIShad certain relation with ascites formation in liver cirrhosis.

Objective To observe changes of the expression of Bcl‐2 and endothelial nitric oxide synthase (eNOS) in lung tissue ,which was used the indifferent treatment doses of recombinant human erythropoietin (rhEPO) of newborn SD model of a new type of bronchial pulmonary dysplasia .To explore its effect on the protection of the new type of bronchial pulmonary dysplasia (BPD) ,and find out the appropriate drug delivery time and dosage .Methods We used the things lipopolysaccharide (LPS) and continuous high oxygen preparation to make the new model of the BPD .We made random normal newborn mice 18 as normal air group ,and then 90 newborn baby mice model of random points normal saline group (group A) ,rhEPO800 group (group B);rhEPO 1000 group (group C) ,rhEPO1200 group (group D) ,rhEPO1400 group (group E) ,in experiment 1 ,7 ,and 14 days ,we were ran‐domly selected 6 executed only lung tissue under liquid nitrogen .Using RT‐PCR and Western blot method to detect the Bcl‐2 and eNOS protein and mRNA expression in lung tissue .Results Compared with the normal air group ,the expression of protein and mRNA of Bcl‐2 in group A was decreased ,while the expression of eNOS was increased .Compared with group B ,C ,D ,E ,with the increase of rhEPO concentration ,the expression of Bcl‐2 protein and mRNA in group A gradually increased ,while the expression of eNOS gradually decreased ,and the expression of the group E was the most obvious ,and the difference was statistically significant (P<0 .05) .Conclusion It is prompted that rhEPO has some treatment function to the new BPD ,while the dose of 1 400 IU/kg of 14 days have the best function .