Objective To study the spatial spillover effects of medical and health resources on the hospital innovation.Methods Based on panel data of 31 provinces of China from 2000 to 2014,and with the method of Spatial Durbin Model(SDM),the paper does the regression with the sample of all provinces,eastern,central and western provinces,through using provincial patent number as explained variable,and using the provincial medical institutions of beds,per capita GDP,health care spending as explanatory variables.Results Medical and health resources have a significant role in promoting the hospital innovation,not only for local province but also for adjacent provinces,namely there is spillover effect;the promotion effect of medical resources for local and neighbouring province hospital innovation is almost the same;for eastern and central provinces,there is a positive effect of medical resources to hospital innovation,and for central province,the spillover effects exist.Conclusion The medical and health resources should be further increased,a provincial communication platform of resources and innovation be built,the east and western provinces spillover effect be promoted,to drive the reform of the supply side with innovation.

Objective:To study the influence of transfer payment on the equalization of medical and health services.Methods:Based on panel data of China's 23 provinces from 2000 to 2014.the medical and health services equalization indexes were measured and developed as the explained index.The explanatory variables such as transfer payment,per capita GDP and health care input were involved.The threshold value of time and transfer payment were applied to developed to conduct the panel threshold regression.Results:Transfer payment significantly promoted the equal distrihntion of health service resources,but the elastic declined if transfered more than 33 billion yuan as the threshold.Meanwhile,there was a threshold effect that the elastic of transfer payment to the equalization of China's medical and health service declined after NCMC in 2003.Conclusion:To further increase transfer payment,it needed to enlarge the new farmers and scope,optimize the equal distribution of health service resources.

Objective:To explore the regularity of acupoint selection of acupuncture for hypertonia after stroke.Methods:The Chinese literatures about acupuncture and moxibustion for post-stroke myotonia from January 1990 to October 2019 in China Academic Journal Database (Wanfang Data), China National Knowledge Resources Database (CNKI), China biomedical literature service system (SinoMed) and Chinese science and technology journal database (Chongqing VIP) were searched. The data of acupoint, meridian and specific acupoints were retrieved and analyzed in Excel 2016. The SPSS statistics 22 and SPSS model 18.0 was used for descriptive analysis and association rule analysis.Results:A total of 32 literatures were included, involving 33 acupuncture prescriptions and 77 acupoints. The total frequency of acupoint use is 398 times. Among them, Hegu with 23 times mentioned was the most frequently used single acupoint, followed by Waiguan with 22 times. Most of the selected acupoints were large intestine meridian of hand Yangming (87 times) and gallbladder meridian of foot Shaoyang (68 times). The total frequency of application of specific acupoints was 386 times. Intersection (123 times) was the most frequently used specific acupoints. Hegu and Waiguan are the core acupoints with the strongest correlation. Conclusions:Hegu is the preferred acupoint for hypertonia after stroke. Large Intestine Meridian acupoints along upper limb are preferred for hypertonia treatment, and Gall Bladder Meridian along lower limb followed. Local acupoints’ selection and distal acupoints’ selection are emphasized.

Education, Dental ; Oral Medicine ; education ; manpower

Objective To compare extramedullary fixation (EF), intramedullary fixation (IF) and dipolar femoral replacement(DFR) in the treatment of intertrochanteric fractures in the elderly patients. Methods From July 1999 to December 2008, 172 old patients with intertrochanteric fractures were treated by either EF, or IF or DFR. The operative procedures, complications and therapeutic effects were compared between the 3 methods. Results The patients included in the present study were followed up for 8 to 36 months (average, 19. 6 months). There were significant differences ( P<0. 05) in incision length, operation time, intraoperative blood loss, functional recovery and complications between the 3 methods. IF had the shortest incision length and the least intraoperative blood loss. DFR had less blood loss than EF. IF had the least operation time, followed by DFR. DFR had the best functional recovery one year postoperatively. IF had shorter rehabilitation and healing time than EF. Conclusions EF is the first choice for intertrochanteric fractures of A 1.1, A 1.2, A 1.3 and A2. 1. IF is more appropriate for the aged and unhealthy patients with intertrochanteric fractures of A1. 1, A1. 2, A1. 3, A2. 1, A2. 2, A3. 1 and A3.2. DFR is fit for the elderly patients with severe comminuted fractures and osteoporosis.

Herbicides ; poisoning ; Humans ; Paraquat ; poisoning ; Poisoning ; therapy

Raman spectroscopy is an optical technology based on the theory of Raman scattering, which is generally used in the research of medical and biological science. Raman spectroscopy can be used to detect the molecular structures and components of proteins, lipids, DNA, and other biological molecules, and provide substantial information about molecules. Thus, Raman spectroscopy is generally considered a "molecular fingerprint", and it has exceptional advantages in medical research. Moreover, this technique can reflect the changes in molecular structures and detect the alterations of chemical constituents in the samples. Raman spectroscopy, given its high sensitivity and specificity in the detection of the biological samples, has been successfully used to detect and diagnose diseases in numerous sites, such as skin, oral mucosa, breast, head, and neck. In this paper, we introduce the application of Raman spectroscopy in stomatology by conducting a review of the literature.
DNA ; Lipids ; Oral Medicine ; Proteins ; Sensitivity and Specificity ; Spectrum Analysis, Raman

Objective: To clinically evaluate the efficacy of electrolyzed oxidizing water (EOW) as a root canal irrigation solution on disinfecting bacteria and removing the smear-layer to keep the non-bacterium state in the root canal. Methods: In the first experiment, 108 single-rooted teeth that needed root canal treatment were randomly divided into two groups. EOW was used as the root canal irrigation solution in the experimental group while 30 ml/L H2O2, saline solution, and 75 g/L EDTA solution were used as controls. Bacteriological examinations were conducted from each tooth before and after treatment with the root canal irrigation solutions. In the second experiment, the 20 fresh human extracted teeth were divided into two groups and treated as same as the first experiment in root canal preparation and irrigation. After irrigation, the apical canal wall was observed using SEM. Results: There was no significant difference in bacterial growth and removing the smear layer between the group using EOW and that using saline solution, 30 ml/L H2O2 and 75 g/L EDTA solution. Conclusion:The results indicate EOW is useful as a clinical root canal irrigation solution.

0.05).[Conclusion]The factors causing reductions should be removed arthroscopically.Arthrocopy may be a useful micro-treatment method for DDH.

Objective To investigate the mechanism of cytokines in brain pathologic changes caused by lipopolysaccharide(LPS).Methods A rat model of LPS was established by injection with a dose of 5mg/kg LPS into thigh vein.60 SD rats were randomly divided into three groups:control group,LPS group,naloxone+LPS group,each group included 20 rats and was subdivided into 4 subgroups(1h,2h,4h,6h respectively).In each subgroup,cerebral pathological changes and concentrations of TNF-α,IL-1β,IL-6 in brain homogenate were investigated.Results Brain homogenate concentration of TNF-α in subgroup LPS 2h was higher than control group[(9 30±0.57) ng/g vs(8.00±0 79)ng/g,P＜0.01],other subgroups have no significant difference from control group. Naloxone group had lower TNF-α level than LPS group.Brain homogenare concentration of IL-1β in subgroup LPS 1h increased apparently[(0.56±0.08)ng/g,P＜0.01],subgroup LPS 2h had no significant change;other subgroups have no significant difference from control group.Natoxone group had lower IL-1β level than LPS group(P＜0.01).but no difference from control group.Brain homogenate concentration of IL-6 in subgroup LPS 2h and 4h were respectively(459.68±79.15)ng/g,(816.07±111.31)ng/g,significantly higher than control group[(377.22±63.73)ng/g,(369.98±34.35)ng/g,respectively].Control group had no significant cerebral pathologic changes,while LPS group showed apparent changes:edema,interstitial substance and mening vessels expanding and hyperaemia,neurosome minification,Nissl's body lost,karyopycnosm,and nucleoli abolition.Naloxone group had lighter neurocyre injuries and brain edema,especially at 2h and 4h.Conclusions After LPS injection,the level of cytokines changed as time goes by,and this fits the brain pathologic changes.Naloxone has protecnve effect on brain tissue in LPS treated rats.Inflammatory cytokines play an important role in the mechanism of cerebral damage in LPS rats.