Objective To develop a set of portable equipment for telemedicine audio and video acquision-wireless portable helmet terminal.Methods The telemedicine images were acquired rapidly in high precision by using micro-camera with automatic focus.Voice analog signals input from microphone were performed A/D conversion by using UDA1344 to form serial digital audio stream.Compressed by helmet master operating system in uCos multitask real-time operating system,the acquired audio and video data were connected with local network by short-distance wireless transmission and then with Internet.Results Wireless portable helmet for telemedicine had such functions as images acquisition,audio transmission,automatic focus,video tape and both-way interphone.The wireless connection with telemedicine server could transmit audio and video in long distance.Conclusion Wireless portable helmet for telemedicine can be applied in remote emergency care,operation and transmission,which will greatly promote the application of tele-medicine.

Objective To realize real-time data transmission of multiple remote terminals ECG monitoring.Methods Mutiple ECG collection terminals were used through a wireless local area network which was linked to servers in the data center though WCDMA.Results ECG data real-time acquisition and monitoring were realized in remote ECG real-time automatic diagnosis system based on network computer.Conclusion Acquisition and control of large amount of real-time data are realized.[Chinese Medical Equipment Journal,2008,29(2):18-20]

Coronary Restenosis ; metabolism ; Heart Valve Diseases ; Humans ; Osteopontin ; metabolism

Acute Coronary Syndrome ; drug therapy ; Anticoagulants ; therapeutic use ; Humans ; Polysaccharides ; therapeutic use

Objective: To study the roles of nuclear factor (NF-kB) and intercellular adhesion molecule 1 (ICAM-1) in cerebral ischemic preconditioning induced brain ischemic tolerance. Methods: A total of 100 clean rats were randomly allocated into 4 groups: control, ischemic, preconditioning, and ischemic preconditioning groups. Both focal and ischemic preconditioning models were induced. The neuroethological score, infarct volume ratio and expression of NF-kB and ICAM-1 in the ischemic region at the corresponding time points were observed. Results: Circled digit one The neurological deficit score in the ischemic group was higher than that in the ischemic preconditioning group. The cerebral infarction volume ratio was higher than that in the ischemic preconditioning group (28.6 ± 3.2% vs. 16.2 ± 3.8%, t = 2.668 [P < 0.05]), and there were significant differences (P < 0.05). Circled digit two The number of NF-KB positive cells in the ischemic preconditioning group were lower than those in the ischemic group at the same time points, but they were higher than those in the preconditioning group, and there were significant differences (P < 0.05). The peak time of the number of NF-KB positive cells in the ischemic preconditioning group was delayed for 48 hours. Circled digit three The numbers of ICAM-1 positive cells in the ischemic preconditioning group were less than those in the ischemic group at the same time points, but they were higher than those in the preconditioning group, and there were significant differences (P < 0.05). Conclusion: Ischemic preconditioning decreases the expression of NF-KB and ICAM-1 after ischemia. The inhibition of inflammatory reaction may be one of the mechanisms of the ischemic tolerance induced by ischemic preconditioning.

Objective To compare extramedullary fixation (EF), intramedullary fixation (IF) and dipolar femoral replacement(DFR) in the treatment of intertrochanteric fractures in the elderly patients. Methods From July 1999 to December 2008, 172 old patients with intertrochanteric fractures were treated by either EF, or IF or DFR. The operative procedures, complications and therapeutic effects were compared between the 3 methods. Results The patients included in the present study were followed up for 8 to 36 months (average, 19. 6 months). There were significant differences ( P<0. 05) in incision length, operation time, intraoperative blood loss, functional recovery and complications between the 3 methods. IF had the shortest incision length and the least intraoperative blood loss. DFR had less blood loss than EF. IF had the least operation time, followed by DFR. DFR had the best functional recovery one year postoperatively. IF had shorter rehabilitation and healing time than EF. Conclusions EF is the first choice for intertrochanteric fractures of A 1.1, A 1.2, A 1.3 and A2. 1. IF is more appropriate for the aged and unhealthy patients with intertrochanteric fractures of A1. 1, A1. 2, A1. 3, A2. 1, A2. 2, A3. 1 and A3.2. DFR is fit for the elderly patients with severe comminuted fractures and osteoporosis.

Hybrid procedure is an method that combines surgery and intervenfional catheterization. As collaboration between surgeon and interventionalist has improved, the procedures for complex congenital heart disease is progressing and developing remarkably. Combining echocardiography monitoring in hybrid surgical procedure of complex congenital heart disease not only reduces side effect of extracorporeal circulation and operation time, but also retrieves blind spot of interventional catheterization for infant and low weight baby. Currently it is applied in the field of atrial septal defect, muscular ventricular septal defect, pulmonary stenosis and post-operation residual shunts or stenosis.

AIM: To investigate the effects of atorvastatin calcium on vascular endothelial cells and circulating endothelial progenitor cells (CEPCs) in hypertensive rats. METHODS: Renal hypertension rat model was constructed with two-kidney-one-clip technique. Twenty-four male SD rats were randomized into hypertension group, statins group and sham-operated group (n=8 each). On the 4th week, the animals in statins group were injected with 20 mg·kg~(-1)·d~(-1) atorvastatin calcium intra-abdominally for 8 weeks. Blood pressure and blood lipid were measured at 4th and 12th week post-operation. On the 12th week, scanning electron microscopy was used to observe the damage of aortic endothelial cells. The circulatory endothelial cell count, CEPCs count, CEPCs proliferation ability, CEPCs adhesion ability and CEPCs apoptosis were also measured. RESULTS: The injury of endothelial cells in statins group was observed, milder than that in hypertension group, but worsen than that in sham-operated group. The numbers of circulatory endothelial cells in hypertension group, statin treatment group and sham-operated group were 5.9×10~6, 3.9×10~6 and 2.0×10~6 respectively, and the CEPCs apoptosis rate was 22.1%±2.1%, 13.4%±1.6 %and 7.4%±1.3%, respectively. Meanwhile, the numbers of CEPCs were 21.63±2.33, 40.38±6.00 and 65.38±2.97, respectively, the proliferative abilities of CEPCs were 0.13±0.01, 0.17±0.01 and 0.29±0.03, respectively, and the adhesion of CEPCs was 12.25±2.49, 21.50±2.20 and 28.88±2.85, respectively. CONCLUSION: (1) The severity of vascular endothelial cell injury is related to hypertension states. (2) Atorvastatin calcium has direct protective effects on endothelial cells, possibly through increasing CEPCs count, reducing CEPCs apoptosis and markedly enhancing reparation ability of CEPCs to endothelial cells.

Objective To optimize the processing method of Codonopsis pilozula prepared product by the factorial design and response surface methodology. Method In the two different optimizing processing, methods were optimized respectively on basis of preplanned experiment design and the percentage of extracts were also determined respectively. Drying temperature and time, bran parching temperature and time respectively as independent variable, their OD value as dependent variable, multiple regression equation was obtained and binomial equation was simulated as well. Results The r2 of Codonopsis pilozula dried product and Codonopsis pilozula parched product were respectively 0.976 4 and 0.987 9, meanwhile their optimized processing methods were drying temperature 80 ℃, drying time 2 hours and parching temperature 250 ℃, parching time 1 minute. Conclusion The effect of independent variable to dependent variable can be analyzed on three-dimensional chart with the factorial design and response surface methodology, consequently it will help to optimize processing method of prepared product.

Objective To establish a suitable formulation for the dispersible tablets of breviscapinum. Methods The preparative process was scanned out by single factor test and orthogonal design. A comprehensive scoring analysis was performed with disintegrating time and rigidity as the indexes. Results The demonstration for the dispersible tablets from the optimized formulation,being totally disintegrated within three minutes and sifted through the sieve in size of the 2nd,show better dissolubility in-vitro in comparison with the common tablets and their quality meets with the requirement for the dispersible in Phamarcopoeia of the People's Republic of China. Conclusion The formulation screened out for the dispersible tablets of breviscapinum is suitable for the production on a large scale.