Brain ; physiopathology ; Female ; Foot ; anatomy & histology ; physiopathology ; Humans ; Meridians

A new method using the ideal mid-facial line as the navigating reference was introduced to improve the outcome of cleft lip repair. Using the verticle coordinate crossing the middle point of the intercanthus line, surgeons could observe and correct the distortion of the fine structures in labial-nasal area. This laser projecting mid-facial-line navigation was repeatable, while not interfere the operating. In conclusion, generalizing laser navigation is a valuable supplementary for cleft lip repair.
Cleft Lip ; surgery ; Face ; Lasers ; Nose ; Oral Surgical Procedures ; methods ; Surgical Flaps ; Treatment Outcome

Acupoint possesses both diagnosing and treating functions according to the acupuncture theory. Acu point plasticity refers to a patho-physiologically dynamic change which is manifested mainly as a neuronal inflammatory reflection in the special area(s) of the body surface under pathological conditions. These responses of acupoint sensitization could activate simultaneously self-healing system in the body and induce the curative effects.
Acupuncture Points ; Acupuncture Therapy ; Animals ; Humans ; Sensation

Acupuncture Points ; Adolescent ; Adult ; Child ; Combined Modality Therapy ; Electroacupuncture ; Exercise Therapy ; Female ; Humans ; Male ; Middle Aged ; Patella ; injuries ; Rheumatic Diseases ; therapy ; Young Adult

Bone Plates ; Bone Screws ; Fracture Fixation, Internal ; Humans ; Maxillofacial Injuries ; surgery ; Oral Surgical Procedures ; Terminology as Topic

Objective To study the possible protective effect of low dose whole body γ-irradia-tion on dopaminergic neuron. Methods In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-in-duced injury mice model,the levels of dopamine (DA) and its metabolites in striata of mice were detec-ted by igh performance liquid chromatogram (HPLC), and neurons (dopaminergic neuron, activated gitter cell and horizontal cell) were counted by immunohistochemical staining after low dose whole body irradiation. Results 3.5 Gy irradiation significantly restored the levels of DA and its metabolites decreased by MPTP. Conclnsion Low dose whole-body γ-irradiation does offer neuroproteetion againstMPTP- mediated damage of striatal dopaminergic nerve fibers.

Decitabine is a methylation inhibitor,which is different from traditional chemotherapy drugs,with new and unique mechanism of action,and represent a new therapeutic concept.Methylation present in almost all cells,by inhibiting DNA methyltransferase,causing hypomethylation of DNA and cell differentiation or apoptosis to anti-tumor effect.In this paper,methylation inhibitor decitabine treatment of hematological malignancies in the application are reviewed.

Objective To investigate the long-term effects of early exposure to general anesthesia and surgery on children's intelligence and sensory integration function.Methods One hundred children who received general anesthesia and non-neurosurgery and non-cardiac-chest surgery operation (anesthesia group),were divided into one time anesthesia and multiple anesthesia.Fifty healthy children who did not receive general anesthesia and operation were as control group.There was no significant difference between 2 groups in sex,age,educational background etc.The Wechsler intelligence scale for children-fourth edition (Chinese version) and the child sensory integration check list were used to evaluate the intelligence and sensory integration function of the 2 groups.Results In development of intelligence,there was no significant difference between 2 groups in full intelligence quotient,verbal comprehension index,perceptual reasoning index,working memory index,processing speed index,general ability index and cognitive productive index.In intelligence structure,the incidence of clinically meaningful difference between verbal comprehension index-working memory index was significantly higher in anesthesia group one time and multiple anesthesia than that in control group [12.0％(6/50) and 26.0％(13/50) vs.6.0％(3/50),P ＜0.05].There was no significant difference in the incidence of sensory integration dysfunction between 2 groups.However,in anesthesia group,the incidence of vestibule balance dysfunction in multiple anesthesia was significantly higher than that in one time anesthesia [44.0％ (22/50) vs.22.0％ (11/50),P ＜ 0.05].Conclusions In general,general anesthesia and surgery during the first three years of life has no significant long-term effects on children's intelligence and sensory integration function.However,the incidence of clinically meaningful difference between verbal comprehension index-working memory index increases in the anesthesia children.Children who received multiple anesthesia and surgery during the first three years of life have a higher incidence of vestibule balance dysfunction.

Objective To analyze the use of serum pepsinogen(PG) and Helicobacter pylori(Hp)-IgG antibody in the screening of atrophic gastritis.Methods A total of 222 patients were divided into two groups according to the gastroscopy results:159 cases in observation group(atrophic gastritis) and 63 cases in control group(non-atrophic gastritis).Patients in observation group were divided into gastric antrum group(50cases),gastric body group (71 cases) and full stomach multifocal group (3 8 cases) according to shrinking parts.The serum PG Ⅰ and PG Ⅱ was determined by enzyme linked immunosorbent assay method,and PGR (PG Ⅰ / PG Ⅱ) was calculated.The serum Hp-IgG antibody was examined by qualitative analysis.Results The serum PG Ⅰ and PGR was (57.82 ± 23.15) μ g/L,4.41 ± 1.82 in observation group,which was lower than that in control group[(125.04 ± 29.36) μ g/L,10.10 ± 2.01],and there was significant difference (P ＜0.01).The positive rate of the serum Hp-IgG antibody was 86.16％(137/159) in observation group,which was higher than that in control group [53.97％ (34/63)],and there was significant difference (P ＜ 0.01).There was significant difference in the serum PG Ⅰ and PGR between gastric antrum group and gastric body group,full stomach multifocal group (P ＜ 0.01).There was no significant difference in the serum PG Ⅰ and PGR among different atrophy degree in gastric antrum group(P＞ 0.05),but there was significant difference in the serum PG Ⅰ and PGR among different atrophy degree in gastric body group and full stomach multifocal group (P ＜ 0.01).Conclusions The serum PG Ⅰ and PGR and Hp-IgG antibody is related to atrophic gastritis.They are helpful to the screening of atrophic gastritis.

Objective To investigate the diagnostic value of the real-time four-dimensional ultrasound imaging examination in the diagnosis of fetal malformations.Methods Four-dimensional ultrasound prenatal audio and video materials,1 008 cases of 12～20 weeks pregnant were retrospectively analyzed,and the dignostic value for the fetal malformation Was obser red by following-up.Results Four-dimensional ultrasound detection of fetal malformations in 26 cases,27 cases of confirmed postpartum fetal malformations,the rate was 96.3%,1 case of missed diagnosis.missed diagnosis rate was 3.7%misdiagnosis rate was 0.Conclusion The dynamic continuous four-dimensional ultrasound could show the activities of the fetus in uterus,diagnosis of most of the morphological structure of fetal malformations,reduced birth defects in children.