1. Molecular typing characterization of food-borne methicillin-resistant Staphylococcus aureus in China
Yao BAI ; Wei WANG ; Lin YAN ; Shuran YANG ; Shaofei YAN ; Yinping DONG ; Bincheng ZHAO ; Yangyang ZHAO ; Jin XU ; Yujie HU ; Fengqin LI
Chinese Journal of Preventive Medicine 2018;52(4):364-371
Objective:
To analyses the antimicrobial resistance and molecular characterization of 21 MRSA isolates cultured from retail foods from different provinces in China, and evaluate the molecular typing methods.
Methods:
Twenty-one MRSA isolates were obtained from national foodborne pathogen surveillance network in 2012 (Chinese salad,
2.Successful Heart Transplantation After Thrombectomy for Acute Ischemic Stroke in a Patient With Heart Failure Complicating With Acute Ischemic Stroke
Yao FENG ; Bincheng WANG ; Guitao ZHANG ; Xiaoying HU ; Ru LIU ; Sheng LIU ; Shujuan LI ; Jie HUANG
Chinese Circulation Journal 2024;39(3):290-293
It remains unclear whether heart transplantation is still feasible on patients who develop neurological complications before surgery and underwent successful neurological treatment.This article reported the diagnosis and treatment process of a heart failure patient complicating with acute ischemic stroke,who underwent successful heart transplantation after thrombectomy for acute ischemic stroke,aiming to provide clinical evidence and decision-making plan on diagnosis and treatment options for this group of patients with severe neurological complications.
3.Advances in several important antimicrobial lipopeptids from Bacillus spp.
Daoming LI ; Ying WANG ; Chao CHEN ; Mingbai ZENG ; Qianru LI ; Qingyun JIA ; Xiuli LIU ; Yongyue HOU ; Chengming FAN ; Yuhong CHEN ; Zanmin HU
Chinese Journal of Biotechnology 2022;38(5):1768-1783
Bacillus spp. are probiotics and can secrete a variety of natural antimicrobiol active substances, of which lipopeptides are an important class. Up to now, about 90 lipopeptides have been identified, and most of them are cyclic lipopeptides. surfactin, iturin, fengycin, bacillomycin and polymyxins are widely studied, and the first three have huge potential for application due to their properties of surfactants and anti-fungal, anti-bacterial, anti-viral, anti-tumor and anti-inflammatory functions. In this paper, the research progress in the structure, function, synthesis regulation, separation, purification and production of surfactin, iturin and fengycin was reviewed. Synthetic biology is a vital means to increase the yield of lipopeptides, and in the future, lipopeptides can be used in crop cultivation, animal farming, food, medicine and petroleum industries as well as environmental protection. Future research should be strengthened on the discovery of new lipopeptides, synthesis of high-activity lipopeptides, economical production of lipopeptides on a large scale and their safety evaluation.
Anti-Bacterial Agents
;
Anti-Infective Agents/pharmacology*
;
Bacillus
;
Bacillus subtilis
;
Lipopeptides/pharmacology*
;
Peptides, Cyclic/pharmacology*