1.Role of PET-CT in diagnosis of lung cancer
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Lung cancer is one of the most common malignancies that are life-treatening to human beings.It ranks the first both in morbidity and mortality of malignant tumors.Early diagnosis,accurate staging,proper treatment and improvement of prognosis are the focuses of related studies in recent years.Imaging diagnosis is the main method for diagnosis of lung cancer.The development of imaging diagnosis and the application of advanced techniques such as CT scan,low-dose helical CT scan,MRI,PET and PET-CT ,play a great role in early diagnosis and staging of lung cancer.Recent researches have demonstrated that ET is one of the most efficient non-invasive methods for diagnosis of lung cancers.However,PET has limitation in precise location of the focus.PET-CT integrates the functions of CT and PET together,and is able to locate the focus precisely.This article mainly reviews the value of PET-CT in the diagnosis of lung cancer.
2.Prevention and treatment of restenosis by integrated medicine undergoing PCI
Guangyin ZHANG ; Junping ZHANG ; Binbin DING
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(08):-
Clopidogrel combinated with aspirin can significantly improve the prognosis of cardiovascular disease in patients with coronary heart disease undergoing PCI, but at the same time, which can increase the risk of cardiovascular hemorrhage. However, plus TCM can significantly improve the therapeutic effect, reduce symptoms of angina, reduce the adverse drug reaction to alleviate the suffering of the patients, in particular, which can reduce the dosage of medicine to improve the quality of life of patients, reduce the application time of using clopidogrel to reduce the financial burden of patients,then improve patient compliance. This review provided reference to combat PCI postoperative treatment using the combination of Chinese and western medicine methods.
3.Improving the synergy of muscle movement is one of the important mechanisms in acupuncture analgesia.
Wenlong ZHANG ; Binbin SHI ; Ranmi ZHOU
Chinese Acupuncture & Moxibustion 2016;36(2):200-202
The efficacy of acupuncture for pain diseases is significant, however, the unified understanding re garding mechanisms of acupuncture analgesia has not been fully reached. In this paper, it is believed that uncoordi nated muscle movement is one of the important causes for pain, while acupuncture could enhance the contact of nerve cells and improve the synergy of muscle movement, so as to achieve the aim of pain relief and even cure.
Acupuncture Analgesia
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Humans
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Muscle Contraction
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Muscles
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physiopathology
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Pain Management
4.The relationship of pancreatic exocrine function with the staging and the size of tumor in the patients with pancreatic cancer
Xiping ZHU ; Xu REN ; Binbin ZHANG
Chinese Journal of Pancreatology 2008;8(4):240-242
Objective To investigate the relationship of pancreatic exocrine function with the pancreatic cancer staging and the size of tumor. Methods N-benzoyl-tryrosyl para-aminobenzoic acid (NBT- PABA) test was used to measure the pancreatic exocrine function of 39 pancreatic cancer patients, 46 chronic pancreatitis patients and 20 normal subjects. In pancreatic cancer group, the relationship of pancreatic exocrine function with the size of tumor (TS) and JPS classification (T factor) was analysed. Results The rate of NBT-PABA excretion in normal subjects, chronic pancreatitis patients were (78.9±15.9)%, (58.6± 19.3)%, respectively; in mild, moderate, severe chronic pancreatitis patients, the values of NBT-PABA were (75.5±23.6)%, (57.9±21.5)%, (45.5±16.7)% ; respectively. The rate of NBT-PABA excretion in pancreatic cancer patients was (47.6±18.3)%, and the rate of NBT-PABA excretion in patients with T3+T4 stage was (42.2±21.70%, and was obviously less than (64.8±11.2)% of T1+T2 stage (P<0.05). Tthe rate of NBT-PABA excretion in patients with TS3+TS4 was (34.8±17.2)%, and was significantly lower than (55.6±23.5)% of TS1+TS2(P<0.05). The rate of NBT-PABA excretion in patients with pancreatic head cancer was (42.5±16.4)%, which was significantly lower than (71.8±9.6)% of the pancreatic body and tail (P<0.05). In the 33 patients with pancreatic head cancer, the rate of NBT-PABA excretion in patients with main pancreatic duct stricture was (54.2±14.1) %, which was significantly higher than (37.6± 14.1)% of patients with main pancreatic duct interruption (P<0.05). There was no significant difference in pancreatic exocrine function between pancreatic cancer and moderate or severe chronic pancreatitis.Conclusions The pancreatic exocrine function was related to the pancreatic cancer staging and the size of tumor to some degree,but it was affected by mass location,and it was also affected by degrees of the pancreatic duct obstruction. The pancreatic exocrine function can not be used to differentiate pancreatic cancer from moderate or severe chronic pancreatitis.
5.Challenge and present status of fecal microbiota transplantation in the treatment of ulcerative colitis
Lulu HU ; Binbin WANG ; Fangxin ZHANG
Chinese Journal of Postgraduates of Medicine 2017;40(3):285-288
Ulcerative colitis (UC) is a subtype of inflammatory bowel disease. Its pathogenesis is not clear and the pathogenesis is complex. Moreover, it is recurrent and its healing is delayed. It is a kind of refractory disease. Its incidence and recurrence rate showed a trend of increasing year by year in our country at present. At the present stage, the main treatment focuses on glucocorticoids, aminosalicylic acid, immunosuppressor and biological agent. Although biological agent can greatly improve the efficacy, there are many problems in clinical treatment for a small amount of refractory patients. The comprehensive intervention combined with non-drug treatment should be performed, so as to achieve the curative effect. Fecal microbiota transplantation (FMT) has attracted people′s attention in recent years. It displays a certain therapeutic effect on the treatment of UC in the active stage, especially refractory recurrent UC. Therefore, the domestic and overseas FMT treatment are summarized in the paper.
6.Research progress on mechanism of autophagy in intestinal mucosal barrier function
Binbin WANG ; Chengfeng WU ; Fangxin ZHANG
Basic & Clinical Medicine 2017;37(3):405-409
Autophagy is a biological process in which cells maintain homeostasis through degradation of cytoplasmic macromolecules and damaged organelles by membrane vesicle structure .Autophagy plays a critical role in maintai-ning survival of intestinal epithelial cells during intestinal mucosal barrier dysfunction .A negative regulator of auto-phagy may lead to intestinal inflammation and tumorigenesis .
7.Preventive and therapeutic strategies of breast cancer-related lymphedema
Binbin TANG ; Xiping ZHANG ; Jinfeng DAI
Chinese Journal of General Practitioners 2017;16(2):159-162
Breast cancer-related lymphedema (BCRL) is one of the common complications after surgery.The pathogenesis of BCRL is unclear,and there is no definitely effective treatment for it.In this article we review the pathogenesis,risk factors and treatment of BCRL,propose the comprehensive strategies for prevention and treatment of BCRL.
8.Quality Standard Study on Danqi Tablets
Binbin FENG ; Jianmei ZHANG ; Huifeng ZHU
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To set up standard method of quality to Danqi Tablets.[Method] Take HPLC to make nature authentication,take reverse HPLC to test the content of salvianolc acid B in the preparation.[Result] The authentication is strong in attribute and has good repetition,the measurement has good linear relation,the recycle rate is 101.7%,RSD 1.77%.[Conclusion] The quality standard can effectively control the quality of Danqi Tablets.
9.Progress in long non-coding RNA of colorectal cancer
Yongjian ZHANG ; Yanlong LIU ; Binbin CUI
Practical Oncology Journal 2015;(6):553-556
Many long non -coding RNA ( lncRNA ) has been found in recent years .The abnormal ln-cRNA expression is closely related to the occurrence and development of tumor .LncRNA can be divided into the tumor promoting and tumor inhibiting according to the function .lncRNA generally overexpresses in solid tumor tis-sue,acts as an important factor involved in tumor invasion ,proliferation and metastasis ,and has been associated with prognosis of neoplasm .This paper describes the current situation of lncRNA research .We mainly introduce several functions of lncRNA which thoroughly researched at present (such as HOTAIR,H19,MALAT-1,Lin-cRNA-p21,GAS5,etc) and their expression in colorectal tumor tissue ,indicating that regulating the expression level of lncRNA may provide a new basis for the diagnosis and treatment of colorectal cancer .
10.A Study on the Relationship between Fatty Liver and Body Mass Index (BMI), Serum Lipid Levels in Old Retired Population
Sumin ZHANG ; Binbin CHEN ; Shaofang YAN
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(01):-
Objective To explore the relationship between fatty liver and body mass index (BMI), serum lipid levels in aging population. Method 748 of retired people (≥45 years) were studied. All participants accepted liver B -mode Ultrasonography examination, height, weight and blood lipid detection. The relationship between Fatty Liver and BMI, serum lipid levels were analyzed. Results The detection rate of Fatter Liver in male and female was 61.8% and 44.6% separately. The detection rate of Fatter Liver was 53.4% in the aging group (45~59 years), while the rate was 51.0% in elderly group (≥60 years). Compared to the 23.07 kg / m2 and 1.58 mmol/L in group without fatty liver, the BMI and serum triglyceride was 26.77 kg / m2 and 2.13 mmol / L in the group suffered the Fatter Lever. There existed statistically significant differences of Body Mass Index and serum Triglyceride level between the group with and without fatty liver (P