1.Clinical observation of hemostatic effection of microporous polysaccharide hemispheres on residual liver after hepatectomy
Journal of Chongqing Medical University 2007;0(07):-
Objective:To evaluate the efficacy and safety of microporous polysaccharide hemispheres(MPH)in control of homostasis on residual liver after hepatectomy. Methods: 60 patients undergoing hepatectomy were randomized to four groups standard group,test group Ⅰ,test group Ⅱ,and control group. Patients in standard group(15 patients)were treated with routine surgical technique to achieve homostasis.In test group Ⅰ(15 patients)the MPH combined with absorbable haemostat were used as hemostatic agents while only the MPH was used in test group Ⅱ(15 patients). The other 15 patients were given absorbable haemostat as control group. The hemostasia time, the amount of blood transfusion during operation and three days after operations were evaluated, the other factors (ALT, Alb, biliary, PT)were also evaluated. Results: In the standard group, hemostasia time was (2.98?1.05) min; the blood transfusion amount was (400?200) ml during operations and (400?200) ml three days after operations; the amount of drainage was (350?100) ml. In the test group Ⅰ, hemostasia time was (3.10?0.85) min; the blood transfusion amount was (200?0) ml during operations and (200?100) ml three days after operations; the amount of drainage was (200?100) ml. In the test group Ⅱ, hemostasia time was (3.20?1.52) min; the blood transfusion amount was (200?200) ml during operations and (200?0) ml three days after operations; the amount of drainage was (150?100) ml, and while in control group, the corresponding results were (5.22?1.82) min, (600?200) ml, (400?200) ml, (400?150) ml, respectively. Satisfactory bleeding control was achieved in 5 patients with routline surgical technique, there was no significant diffterence among them. The incidence of hemostasis in control group (33%)was significantly lower than that in standard group(80%) and all test groups(73.3%, 66.7%, respectively). No hemostatic complications were noted in either group. Conclusion: MPH provides rapid, effective and safe hemostasis after hepatectomy, which can be applied in hepatectomy.
2.Relationship between perfectionism and depression in college students:mediation of self-esteem
Chinese Journal of Behavioral Medicine and Brain Science 2013;(6):548-549
Objective To explore the mediation effect of self-esteem on the relationship between perfectionism and depression in college students.Methods Totally 292 college students completed Frost Multidimensional Perfectionism Scale (FMPS),Hewitt Multidimensional Perfectionism Scale (HMPS),Slaney Almost Perfect Scale-Revised (APS-R),Rosenberg Self-esteem Scale (SES) and Beck Depression Inventory (BDI).Results Maladaptive perfectionism was positively correlated with depression (r =0.54,P < 0.01),and negatively correlated with self-esteem (r =-0.55,P < 0.01).Adaptive perfectionism was not correlated with depression (r =-0.09,P > 0.05),and was positively correlated with self-esteem (r =0.36,P <0.01).Self-esteem partially mediated the association between maladaptive perfectionism and depression.The partial mediation effect was significant (P <0.05).The mediation model fitted the data well (GFI =0.986,CFI =0.988,NFI =0.981,TLI =0.970,RMSEA =0.075).Conclusion Self-esteem has partially mediating effect on perfectionism and depression.
3.A Summary of Treatment of Angina Pectoris with Traditional Chinese Medicinal Injection
International Journal of Traditional Chinese Medicine 2009;31(3):285-286
Angina pectoris is a common belonging to the diseases of "Chest Bi-syndrome", "precordial pain" or "syncopal precordialgia" in traditional Chinese medicine. Clinically Shengmai injection, Acanthopanex injection, Breviscapine injection, Fleabane injection, Safflower injection, Astragalus injection, Shuxuetong injection, Xin-ding injection and Panax notoginsenoside injection were commonly used to treat the disease with good clinical curative effect.
4.Correlation Between CT Manifestation Types and CD4+T Lymphocytes in AIDS Combined with Pneumocystis Pneumonia
Chinese Journal of Medical Imaging 2017;25(6):447-451
Purpose To investigate the CT features of different pneumocystis pneumonia (PCP) types in AIDS as well as the relationship between different PCP types and CD4+ T lymphocyte count,in order to deepen the understanding and improve the diagnosis and treatment of PCP.Materials and Methods The CT examination data of 102 AIDS patients with PCP were retrospectively analyzed,the CT findings were divided into 6 types,and CD4+ T lymphocyte count of the 6 PCP types was statistically analyzed.Results ① The CT findings of PCP were divided into the following 6 types:transparent ground-glass type (42 cases,41.2%),muddy ground-glass type (17 cases,16.7%),solid variant (11 cases,10.8%),cystic variant (6 cases,5.9%),interstitial type (19 cases,18.6%),and mixed type (7 cases,6.9%).② The CD4+ T lymphocyte count of different PCP types was analyzed,and the difference was statistically significant (F=2.672,P<0.05).Further pairwise comparison showed that the CD4+T lymphocyte count of transparent ground-glass type was higher than that of solid variant and cystic variant (P<0.05),and there was no significant difference between the other groups (P>0.05).Conclusion CT findings of AIDS with PCP have certain characteristics,and it is helpful to deepen the understanding of PCP through imaging classification.There is a certain correlation between different PCP types and CD4+T lymphocyte count,and it is helpful to improve the diagnosis and treatment of PCP by analyzing the correlation.
5.CT manifestations of AIDS patients with opportunistic infections of the lungs
Journal of Medical Postgraduates 2014;(12):1340-1344
Lung opportunistic infections are most common pulmonary complications in patients with advanced AIDS .A variety of pathogens can cause lung infections .Lung CT findings show the complexity and diversity for these complications .Analysis of CT fea-tures of pulmonary infection caused by different pathogens has an important clinical significance on strengthening the awareness of AIDS complicated with pulmonary opportunistic infection and improving the clinical treatment effect .
6.Relationship between executive function deficits and violent behaviors in male adolescents
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(07):-
Objective To explore the roles of executive function deficits in adolescent violent behaviors. MethodsAccording to the findings of general state questionnaire,modified overt aggression scale and interview,93 male juvenile delinquents were randomly divided into violent antisocial group(n=47) and nonviolent antisocial group(n=46).Besides,50 male adolescents in vocational schools were served as normal controls.All the participants were subjected to Wechsler adult intelligence scale(WAIS) test,Wisconsin card sorting test(WCST),Stroop color-word test(CWT) and Tower of Hanoi(TOH) test. Results There was no significant difference in IQ between violent antisocial group and nonviolent antisocial group(P0.05).In CWT,violent antisocial group and nonviolent antisocial group had significant difference with normal control group in number of correct responses of Stroop interference effects(SIE)(P0.05).In TOH,the total time spent in violent antisocial group and nonviolent antisocial group was significantly longer than normal control group(P0.05). Conclusion There exists executive function deficits in male adolescents with unlawful acts,and violent behaviors may have a closer relationship with executive function deficits.
7.Enriched Environment and Stroke Rehabilitation (review)
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):47-52
Abstract: An enriched environment refers to conditions that facilitate sensory, cognitive, motor, and social stimulation. Behavioural,cellular and molecular studies have revealed significant effects of enriched environments on rodents and other species. Post-ischemic housing in an enriched environment improves functional outcome, modifies gene activation, induces alterations in the expression of N-methyl-D-aspartic acid (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits, increases dendrite branching and number of dendritic spine in pyramidal neurons in layers II/III in the contra-lateral cortex, induces structural changes in synaptic junctions. Furthermore, it alters lesion-induced progenitor cell differentiation and interacts with necrotic grafting. The idea of environmental enrichment has been applied to clinical stroke rehabilitation and is getting more and more attention. This review will summarize experimental effects of enriched environment on post-ischemic rehabilitation and the clinical application of enriched environment in stroke rehabilitation.
8.The value of serum-ascites albumin gradient for predicting esophageal-gastric fundus variceal bleeding
Caifeng JIANG ; Bin SHI ; Weifen XIE
Chinese Journal of Digestion 2011;31(9):591-593
Objective To screen the risk factors of esophageal-gastric fundus variceal bleeding,in order to provide a more economical and less invasive method for predicting esophageal-gastric fundus variceat bleeding. Methods A total of 168 diagnosed liver cirrhosis patients accompanied with ascites and 60 cases of liver cirrhosis patients with primary hepatic carcinoma were enrolled. Followed up for one year, the esophageal-gastric fundus variceal bleeding was observed and analyzed with statistic methods. Results Unconditional single factor logistic regression model analysis indicated that albumin level of ascites, serum-ascites albumin gradients (SAAG), platelets, activated partial thromboplastin time (APTT), portal vein width, length and thickness of the spleen were independent risk factors,age and serum albumin were protective factors. Multifactor analysis indicated SAAG, APTT, and portal vein width were the independent risk factors, OR was 3.559 , 2.468 and 2. 608 respectively.After building receiver operating characteristic curve, the best SAAG cut-off value was 18.50 g/L, of which the sensitivity was 96.3% and specificity was 56.3%. Conclusion SAAG has good value in predicting esophageal-gastric fundus variceal bleeding.
9.EFFECTS AND CLINICAL SIGNIFICANCE OF PROGLUMIDE IN GASTRIN-STIMULATING CELL PROLIFERATION ON HUMAN COLON CELL LINE SW480
Bin XIE ; Shuangwu HE ; Daike WANG
Tumor 2001;(2):88-90
Objective To investigate the role and clinical significance of proglumide (PGL) in gastrin-stimulating cell proliferation on human colon cell line SW480.Methods Effects of proglumide on the viable cell count (A value), IP3 (CPM value), [Ca2+]i and PKC activity of human colon cell line SW480 were evaluated in vitro by MTT assay, 3H-myo-inositol incorporation, fluorescence measurements and γ-32P-ATP incorporation. Results The results showed that A value of PGL+PG group is lower than that of PG or control group (P<0.01 in both groups); The concentration of IP3 or [Ca2+]i in PGL+PG group is lower than that in PG group (P<0.05). Conclusion These results indicate effects of proglumide may be through the phosphoinositide signalling pathway on gastrin-stimulating cell proliferation in human colon cell line SW480. It will provide an experimental evidence for antisingnal transduction therapy for patients with colon cancer.
10.The Chinese version of impulsive-premeditated aggression scale in adolescents with aggression:its reliability and validity
Yi QIAO ; Bin XIE ; Mingdao ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(4):366-368
Objective The purpose of the present study was to examine the reliability and validity of the Chinese version of the impulsive-premeditated aggression scale (IPAS) in a sample of Chinese adolescents with aggression. Methods 126 adolescents completed the IPAS,Barratt impulsive scale and self-report questionnaires. In order to assess test-retest reliability, the IPAS was re-administered to 30 participants 3 weeks later.Results Item analysis showed that IPAS had satisfactory item discrimination, 6 items were excluded in the later analysis. The internal consistency of the IPAS Cronbach alpha was 0.77 and the test-retest reliability was 0.74.Exploratory factor analysis demonstrated two stable factors of aggression with good internal consistency and construct validity, the value of KMO was 0.646, the χ2 value of Bartlett test was 691.93 ( P <0.001). The confirmatory factor analysis showed that the value of χ2/df,GFI,AGFI,RMSEA were 1.42,0.874,0.837 and 0.058 respectively.The whole scale and the two secondly scales all correlated with BIS-11 and MOAS.Conclusion The results of the current study indicate that the Chinese version of the IPAS is a useful tool to subtyping aggressive behavior among adolescents, but it still need to be modified to apply in China.