Diabetic retinopathy (DR) is a common complication of eye in diabetics and is one of the major causes of blindness in adults.The current treatments of DR include surgery and laser therapy,but this does not fundamentally cure DR.Recent studies have found that mesenchymal stem cells (MSCs) for cell therapy to DR have a wide range of applications.MSCs have regenerative potential and play a role in the repairment of the retina,but the survival and homing ability of MSCs are poor after transplantation,which reduces the therapeutic efficiency of MSCs.Statins have a variety of beneficial effects independent of lipid regulation,which can promote the proliferation of MSCs and inhibit the apoptosis of MSCs.This paper reviewed the application and mechanism of MSCs combined with statins in the treatment of DR.

Objective: To evaluate the therapeutic efficacy of acupuncture plus Chinese medicinal fumigation and washing in treating edema of the affected limb in post-stroke hemiplegia. ＜br> Methods: Two hundred patients with edema of the stroke-affected limb from our hospital were randomized into two groups according to their visiting sequence. In the observation group, 100 subjects were intervened by acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics, while the other 100 subjects in the control group were only given diuretics. The therapeutic efficacy was evaluated after successive 2-week treatments. ＜br> Results: The total effective rate was 90.0% in the observation group, significantly higher than 66.0% in the control group, indicating that there was a significant difference in comparing the overall therapeutic effect (P＜0.01). ＜br> Conclusion: Acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics is effective in treating edema of the affected limb in post-stroke hemiplegia.

Objective:To investigate the expression and the effects of CD40/CD40L in lung tissue of rabbits with hemorrhagic shock.Methods:18 healthy rabbits were randomly divided into control group(group A),hemorrhagic shock 1 hour group(group B) and hemorrhagic shock 2 hours group(group C),with 6 rabbits in each group.Except the rabbits in the control group,rest rabbits were made into hemorrhagic shock models with lung injury according to Wiggers modified method.TNF-?、IL-10 in plasma were measured by ELISA.Expressions of CD40 and CD40L in lung tissue were measured by immunohistohemistry.Water quantity and pathological change in the lung were observed.Results:The lung of group B and C displayed obvious injury,water quantity increased(P

OBJECTIVE To learn about the state of disinfecting quality and its impact factors of our hospital in recent 10 years.METHODS According to GB15982-1995 and GB15981-1995 the sampling and surveillance were carried out to the objects concerned for disinfecting in the hospital.RESULTS It showed ascent trend in its entirety for the qualified rate of sample surveillance(70.53-96.34%).The qualified rates of applying disinfecting liquid,medical treatment necessities and pressure steam sterilizer were also higher in the surveillance each year.CONCLUSIONS The lows and regulations correlated with disinfection and operating technological specification have become more and more perfect and flawless,supervision and management also have been intervened and strengthened,and the level of the consciousness and knowledge of disinfection among the staff have had elevation,all these have elevated the disinfection job of the hospital in quality.

The goal of the consensus initiated by the European Crohn’s and Colitis organisation(ECCO)was to establish the European consensus guidelines for surgical treatment of ulcerative colitis. The consensus covered four parts:the preoperative phase,intraoperative phase,postoperative phase and special situations. This consensus guideline was published in“Journal of Crohn’s and Colitis”and posted on the websites of ECCo in 2015. Interpretation of main points of this consensus was presented in this paper.

Objective To investigate the effect of spironolactone combined with valsartan on renal function in patients with early diabetic nephropathy.Methods 158 early diabetic nephropathy patients from May 2014 to June 2015 in department of endocrinology of Nanxun People’s Hospital of Huzhou were selected and divided into control group (79 cases) and experimental group (79 cases).The control group were treated by valsartan and the experimental group were treated with spironolactone on the basis of control group.The changes of renal function, potassium ion and blood rheology were observed and compared after treatment.Results Compared with control group post-treatment, the systolic pressure and diastolic pressure levels were lower, plasma urinary albumin excretion rates (UAER) level was lower (P <0.05), albumin (Alb), serum creatinine (Scr), blood urea nitrogen ( BUN) , creatinine clearance ( Ccr) and K +levels had no significant differences, whole blood specific viscosity, plasma specific viscosity and whole blood specific reduced viscosity were lower ( P <0.05 ) in experimental group.Conclusion Spironolactone combined with valsartan could effectively improve clinical efficacy of patients with early diabetic nephropathy , improve the renal function of patients, recover ion disorder and reduce blood viscosity.

Supernumerary tooth is common,but symmetrical supernumerary tooth on both sides is rare.A case of symmetrical supernumer-ary tooth of maxillary posterior teeth area is reported in this paper.

Atlanto-axial complex is the most important functional unit of the cervical spine.Atlanto-axial instability or dislocation,one of the most serious pathologies in spinal surgery,is often managed by posterior atlantoaxial fixation and fusion.Several posterior fixation techniques have been used to stabilize the atlanto-axial complex,including wire/cable-bone fixation,Halifax clamps,transarticular screw fixation,screw-plate fixation and screw-rod fixation.For atlanto-axial dislocation that cannot be reduced with skull traction before operation,intraoperative reduction is often needed.Current intraoperative reduction techniques can be classified into transoropharyngeal surgical release followed by posterior reduction and fixation,transoropharyngeal reduction and fixation,and posterior reduction and fixation using screw-rod system according to approaches.Furthermore,posterior reduction can be performed using elevating-pull,leverages,and cantilever techniques.This study reviews the intraoperative reduction and fixation techniques mentioned above.

Brain tumor stem cells (BTSCs) play a key role in tumorigenesis and tumor development.There are a group of special markers in the surface of brain tumor stem cells,which can sorts stem cells,precursor cells and cancer stem cells.In recent years,the studies of CD133,Nestin,high-mobility group A1,A2B5 have made some breakthroughs.

ObjectiveTo identify the proteins presented variation during ischemia/reperfusion injury (I/RI) in liver transplantation (LT).MethodsAt Mar.2009,a total of nine liver sample tissues,three samples obtained from each donor liver at three different time points,were studied.The time points were as follows:(1) the time point immediately after donor liver was harvested (T1) ; (2) the time point just before the anastomosis of hepatic artery and potal vein (T2),during this time period the donor liver was kept in ice cold and transported,then back-table prepared,during time from T1 to T2,ischemia injury occurred; (3) the time after donor reconnected to the recipient (T3),during which the donor liver was subjected to reperfusion injury.The three time points represent normal control,ischemia injury,and reperfusion injury respectively.By using method of 2DE-MALDI-TOF and mass-spectrum,the differential expression of these protein at T1,T2,and T3 time point were compared.ResultsFrom the 1580 proteins that were isolated,19 ischemia/reperfusion injury (I/RI)-related proteins that varied markedly from time point T1 to T2 and from time point T2 to T3 were identified.They were metabolic enzyme,molecular chaperone,redoxase,cytoskeleton protein,signal transduction protein,and binding protein,respectively.The character of each protein was further analized based on their functions.ConclusionsFor the first time,we detected the protein related to I/RI during LT.We obtained independent proteomics information of ischemia injury,and reperfusion injury,respectively.Further functional analyses of these proteins may improve the understanding of the critical biological processes during I/RI.Medicine intervention on the I/RI-related proteins may result in improved survival of the recipients.