Objective To study the application of waveforms in treatment of peripheral facial paralysis with electroacupuncture. Methods 66 patients with peripheral facial paralysis were divided into two groups: treatment group (34 cases) and control group(32 cases). All the patients were acupunctured at the similar points with electroacupuncture, while the disperse-dense wave and the discontinuous wave were used successively in the treatment group, and the disperse-dense wave was used alone in the control group. Results There were significant differences between the two groups in the total effective rate and the days for cure (P<0.01). Conclusion The effect of alternate disperse-dense wave and discontinuous wave is superior to that of disperse-dense wave alone in electroacupuncture treatment for peripheral facial paralysis.

Objective To observe the clinical effect and the incidence of neuralgia of acupoint injection with nerve growth factor onRamsay Hunt syndrome. Methods 65 patients with Ramsay Hunt syndrome were divided into treatment group (n=33) and control group(n=32). All the patients were treated with the anti-virus and glucocorticoid medicine, and were acupunctured at the similar points with electroacupuncturewith the disperse dense wave. The treatment group was injected with mouse nerve growth factor at the acupoints. 2 days offevery 5 times, 10 times as a course for 2 courses. The treatment effect and the incidence of sequelae neuralgia after 3 months were compared.Results The total effective rate of treatment group (93.9%) was significantly higher than control group (71.9%) (P<0.01). The incidenceof sequelae neuralgia of the treatment group (6.3%) was significantly lower than the control group (26.7%) (P<0.01). ConclusionAcupoint injection of mouse nerve growth factor can improve the efficacy and reduce the incidence rate of sequelae neuralgia in patientswith Ramsay Hunt syndrome.

Objective To investigate the correlations of serum markers of hepatitis B virus,HBV DNA load and liver function indexes[alanine aminotransferase(ALT)and aspartate transaminase(AST)]in the peripheral blood.Methods Clinical data of 483 patients who were diagnosed with chronic hepatitis B and treated between March 2014 and March 2016 in Tongji hospital were retrospectively analyzed.The serum markers of hepatitis B virus were quantitatively detected by chemiluminescent microparticle immunoassay.Serum HBV DNA load was measured by real-time fluorescence quantitative PCR,and ALT and AST by continuous ultraviolet monitoring.Results There was no correlation between the HBsAg content and HBV DNA load or the rates of abnormal ALT(>41 U/L)and abnormal AST(>35 U/L)(P>0.05).The HBeAg content was not correlated with HBV DNA load and the rates of abnormal ALT(P>0.05),but weakly with the rate of abnormal AST(r=0.21,P<0.01).Although the anti-HBe content was not correlated with the rate of abnormal ALT(P>0.05),it was weakly related to HBV DNA load and the rates of abnormal AST(r=0.16,P<0.05;r=0.19,P<0.01).The anti-HBc content had weak correlations with HBV DNA load,the rates of abnormal ALT and abnormal AST(r=0.25,P<0.01;r=0.29,P<0.01;r=0.29,P<0.01).The logarithm value of HBV DNA load was weakly positively correlated with ALT and AST(r=0.24;r=0.29).Conclusion Quantitative detection of both serum markers and the DNA of hepatitis B virus can complement each other,and when combined with detection of liver function indexes,it will help understand the damage of liver tissue.

Objective To explore the size changes of erythrocytes infected with Plasmodium malariae,so as to improve the basic?level experimenters’microscopy capabilities for P. malariae identification in thin blood smears. Methods The micro?scopic features of erythrocytes infected with P. malariae in thin peripheral blood smears were observed,and a microscope image processing software was used to measure and analyze the diameter changes of the erythrocytes infected with P. malariae. Re?sults The diameter of erythrocytes infected with P. malariae decreased significantly compared with that of the normal erythro?cytes. The three parameters in this study:the diameter of erythrocytes,the value of diameter variation,and the ratio of diameter variation varied at different developmental stages of P. malariae,and the differences were statistically significant(all P<0.01). The variances of the three parameters grouped by different cases or different developmental stages in different cases were ana?lyzed,all showing statistically significant differences(all P<0.01). Conclusion All the developmental stages of P. malariae will cause the decrease of the diameters of infected erythrocytes in peripheral blood smears,but the influence on the diameter of erythrocytes,value of diameter variation,and ratio of diameter variation varies at different developmental stages in different cases.

Objective To compare the two kinds of the single nostril transsphenoidal approach of minimally invasive surgery of pituitary adenoma and analyze the clinical data ,and then provide references for clinical diagnosis and treatment .Methods The prospective study methods were used in the study .A total of 54 cases of pituitary tumor patients were collected , they were randomly divided into microscope group ( 31 cases ) and neural endoscopic group (23 cases).The operation time,intraoperative blood loss,hospital stay,the resection rate,postoperative complications ( mainly observed transient postoperative insipidus and transient electrolyte disorder ) , the hormone levels , and the comparison the results of patients ,follow-up within 1 year were observed .Results The operation time of microscope group(121.3+19.4)min was longer than that of the neuroendoscopic group (78.5 ±7.8)ml,but the intraoperative blood loss in the microscope group was less than that of the neuroendoscopic group [(50.3 ±3.2) mL vs (78.5 ± 7.8)mL,t=0.993,1.032,all P>0.05].The postoperative hospital stay [(8.7 +1.1) d vs (9.1 +2.3) d,t=2.897,P>0.05],the resection rate(93.5% vs 91.3%,χ2 =3.191,P>0.05) had no significant differences be-tween the two groups .The postoperative complications ( including transient insipidus and transient electrolyte disorder ) also had no obvious differences .The analysis of the endocrine hormone levels of different tumors found that there were no significant differences between the microscope group and neuroendoscopic group .The levels of these pre operative and postoperative hormones were as follows:PRL[(387.3 ±100.8)μg/L vs (145.3 ±27.4)μg/L and (390.2 ± 133.7)μg/L vs (148.4 ±57.2)μg/L],GH[(63.4 ±5.7)μg/L vs (10.6 ±2.4)μg/L and (65.6 ±6.2)μg/L vs (12.4 ±1.6)μg/L],ACTH[(202.9 ±73.7)ng/L vs (38.5 ±4.6)ng/L and (206.8 ±78.6)ng/L vs (35.6 ± 2.5)ng/L],they all had significant differences (t =1.456,1.301,0.973,1.034,0.774,0,732,all P <0.05). Conclusion The curative effects of the two surgical treatment of pituitary adenoma have no obvious differences ,they have advantages of minimally invasive , safe and effective, but the microscopic surgery has less bleeding , while neuroendoscopic surgery can shorten the operation time .

Treated uroschesis due to spinal cord injury in 32 cases with acupuncture therapy (acupuncture group) and compared with Neostigmine injection (control group). In acupucture group, 10 cases got clinical recovery, 17 efficacy and 5 inefficacy, with an effective rate of 84.4%; among 32 cases in control group, 3 cases got clinical recovery, 15 efficacy and 14 inefficacy, the effecrive rate was 56.2%.

Objective:To investigate procalcitonin and C-reactive protein levels in diarrheal patients who underwent irinotecan che-motherapy. Methods:Procalcitonin and C-reactive protein were detected among 85 diarrheal and 63 non-diarrheal patients after irinote-can chemotherapy. Results:According to WHO classification, patients without diarrhea are classified as grade 0, whereas patients with diarrhea can be classified as gradesⅠ-Ⅳ. In grades 0,Ⅰ,Ⅱ,Ⅲ, andⅣpatients, the levels of procalcitonin were 0.29 ± 0.17, 0.30 ± 0.18, 0.36 ± 0.20, 1.24 ± 0.22, and 2.15 ± 0.26 ng/mL on the second day, respectively. However, on the fourth day, the procalcitonin lev-els were 0.28 ± 0.15, 0.30 ± 0.14, 0.34 ± 0.18, 2.00 ± 0.22, and 2.40 ± 0.28 ng/mL, respectively. Moreover, in grades 0,Ⅰ,Ⅱ,Ⅲ, andⅣ, the levels of C-reactive protein were 6.06 ± 1.85, 6.12 ± 1.16, 6.20 ± 1.68, 22.62 ± 4.55, and 31.26 ± 5.23 mg/L on the second day, respectively. On the fourth day, the C-reactive protein levels were 5.80 ± 1.82, 5.94 ± 1.14, 6.15 ± 1.55, 30.52 ± 4.74, and 38.67 ± 5.68 mg/L, respectively. No significant difference was found between the procalcitonin and C-reactive protein levels of stagesⅠandⅡpa-tients (P>0.05), but a significant difference was found between stagesⅠ, andⅡpatients and stagesⅢandⅣpatients (P<0.05). Con-clusion: Monitoring levels of procalcitonin and C-reactive protein may be helpful in the early evaluation of the severity of diarrhea. This process has prognostic effect and can be used to assess whether patients have enterogenous bacterial infection. Monitoring the lev-els of these proteins has certain clinical value and can be used to guide early anti-infection therapy.

Objective To study the influence on xerostomia of radiotherapy in treatment of head and neck cancer.Methods 82 cases with head and neck cancer from August 2005 to January 2006 were analyzed retrospectively.All patients were asked about their xerostomia at the end of every week.Then xerostomia and xerostomia-related problems were analyzed.Results There were obvious difference in the incidence rate of xerostomia( ?2=26.24,P 0.05).Conclusion During radiotherapy,acute radiation xerostomia may happen.The rate of it is different.depending on the radiation dose to be accepted while not on the age.

Objective To explore the application of mesangial thyroid resection in papillary thyroid carcinoma(PTC) with central lymph node dissection,and its influence on postoperative recurrence.Methods 76 cases with PTC were divided into two groups according to random number table,each group in 38cases.The control group was given primary lesions radical prostatectomy and routine central lymph node dissection,the treatment group was given primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection.The parathyroid function,injury of recurrent laryngeal nerve and local recurrence were compared between the two groups.Results Compared with before surgery,the levels of serum PTH and blood calcium were significantly decreased at the 1st,3rd day after surgery (all P ＜ 0.05),while there were no statistically significant differences in serum PTH and blood calcium at the 7th day after surgery(all P ＞0.05).The levels of serum PTH and blood calcium at the lst,3rd,7th day after surgery between the two groups had no statistically significant differences(all P ＜ 0.05).The incidence rate of injury of recurrent laryngeal nerve in the treatment group was significantly lower than that in the control group (5.3％ vs.21.1％,x2 =4.15,P ＜ 0.05).The secondary surgery rate and local recurrence within 2 years in the treatment group were significantly lower than those in the control group (0％ vs.15.8％,2.6％ vs.18.4％,x2 =6.51,4.69,all P ＜ 0.05).Conclusion Primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection can be used as theroutine operation for PTC,which can effectively produce complete dissection,reduce injury of recurrent laryngeal nerve and local recurrence.

Objective To introduce the recent studies about the lymph node-targeted chemotherapy for gastric carcinoma. Methods The literatures on the lymph node-targeted chemotherapy for gastric carcinoma in recent years were collected and reviewed. Results The lymph node-targeted chemotherapy for gastric carcinoma was effective because it couled improve the drug concentrations in regional lymph node. Conclusion As a part of multiple treatments for gastric carcinoma, lymph node-targeted chemotherapy will be further developed.