1.EFFECTS OF THROMBOLYSIS WITH ULTRASOUND ON THE STRUCTURE OF ERYTHROCYTE AND ITS SAFETY THRESHOLD
Journal of Pharmaceutical Analysis 2006;18(2):139-141
The study was to investigate thrombolysis in vitro with ultrasound, and to discuss effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold under different ultrasound intensity and exposure time. The structure of erythrocyte in thrombus was evaluated under light microscope. The relationship between the structure of erythrocyte in thrombus and ultrasound intensity and exposure time was obtained. The results showed that ultrasound eliminated the thrombus. According to the change of the structure of erythrocyte in thrombus and ultrasound intensity and exposure time, the effects of thrombolysis with ultrasound could be divided into three kinds of areas: the A, B, C area. The area A was the safe area, the area B was the relatively safe area, and the area C was the irreversible damage area. The study suggested that ultrasound intensity and exposure time had significant impact on the structure of erythrocyte. Stronger ultrasound intensity or longer exposure time could cause erythrocytes irreversible damage. It could accelerate thrombolysis and shorten the exposure time that the ultrasound intensity was little bit increased. The study of effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold were important for practical applications.
2. Effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold
Academic Journal of Xi'an Jiaotong University 2006;18(2):139-141
The study was to investigate thrombolysis in vitro with ultrasound, and to discuss effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold under different ultrasound intensity and exposure time. The structure of erythrocyte in thrombus was evaluated under light microscope. The relationship between the structure of erythrocyte in thrombus and ultrasound intensity and exposure time was obtained. The results showed that ultrasound eliminated the thrombus. According to the change of the structure of erythrocyte in thrombus and ultrasound intensity and exposure time, the effects of thrombolysis with ultrasound could be divided into three kinds of areas: the A, B, C area. The area A was the safe area, the area B was the relatively safe area, and the area C was the irreversible damage area. The study suggested that ultrasound intensity and exposure time had significant impact on the structure of erythrocyte. Stronger ultrasound intensity or longer exposure time could cause erythrocytes irreversible damage. It could accelerate thrombolysis and shorten the exposure time that the ultrasound intensity was little bit increased. The study of effects of thrombolysis with ultrasound on the structure of erythrocyte and its safety threshold were important for practical applications.
3.AN ANALYSIS OF THE MICROSTRUCTURE CHARACTERISTICS IN HUMAN KIDNEY WITH ULTRASONIC BACKSCATTERING
Bige YAN ; Dean TA ; Rong WANG
Journal of Pharmaceutical Analysis 2005;17(1):66-71
Objective To investigate the microstructure characteristics in human kidney with the WD cepstrum of ultrasonic backscattering. Methods By using this method, an analysis of the backscattering signals of normal and pathological human kidney in vitro was made and the mean spacing of the scatterers of biological soft tissues was estimated, then compared the means of this new approach with the means of the AR cepstrum. Results The results show that the mean spacings of the scatterers of the two different kidney tissues are noticeably different, which reveals the fact that the WD cepstrum works more effective than the AR cepstrum in showing the features of the microstructure of soft tissues. Conclusion The WD cepstrum is an effective mean to analyze the ultrasonic scattering signals and determine the features of the mean spacing of the scatterers of soft tissues. This method provides more available clinical diagnosis and improves the results of mean spacing of the scatterers of soft tissues.
4.Finite element analysis in simulations of ultrasonic elastography.
Tingting ZHAO ; Bige YAN ; Wubin NIU
Journal of Biomedical Engineering 2011;28(1):138-147
In this paper, the soft tissue strain under different circumstances was analyzed by using the finite element analysis (FEA) and the Matlab's toolbox. The scope of application of ultrasonic elastography was estimated in theory. The results of analysis indicated the limitation of ultrasonic elastography, and its application prospects. In addition, some characteristics of breast cancers, which are meaningful in clinics, may be estimated using this method.
Computer Simulation
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Connective Tissue
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diagnostic imaging
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Elasticity
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Elasticity Imaging Techniques
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methods
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Finite Element Analysis
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Humans
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Image Processing, Computer-Assisted