2.Application of endoscopic retrograde cholangiopancreatography in pancreatic diseases in children
Chinese Journal of Practical Internal Medicine 2001;0(04):-
ERCP has revolutionized the treatment of adult pancreatic diseases.After many years of clinical application,the current adult treatment technology has reached a mature state.With the development of pediatric endoscopic techniques,in recent years,therapeutic ERCP techniques in children has been progressing from the research stage to the stage of practical application and has become an important treatment for pancreatic diseases in children.This article mainly reviews on ERCP in diagnosis,treatment and complications of pancreatic diseases in children.
3.Surgical treatment of the severely displaced supracondylar fracture of the humerus in children
Chinese Journal of Orthopaedic Trauma 2008;10(3):234-237
Objective To study the curative effects of surgical treatment of the severelv displaced supracondylar fracture of the humerus in children. Methods A retrospective investigation was conducted on 316 children with severely displaced supracondylar fracture of the humerus who had been treated with operation in our hospital from June 2001 to June 2006.There were 215 boys and 101 girls,with an average age of 7 years old(range,1 to 14).All were treated with open reduction and internal fixation by Kirschner wire,plaster external fixation after operation,and functional training 2 to 4 weeks postoperatively. Results All the 316 cases were followed up for over 6 months to 5 years, with an average of 2 yearS and 10 months. The functional recovery of the postoperative elbow joint was evaluated by Flynn's criteria.Of them,253 cases were rated as excellent,34 as good,25 as satisfactory,and 4 as poor.Cubitus varus deformity was found in 27 cases. Conclusions Although closed reduction and external fixation is the frst choice for the pediatric supracondylar fracture of the humerus, open reduction and Kirschner wire fixation is necessary for the severely displaced supracondylar fracture of the humerus,including those suffering from failed manipulative reduction,open fracture,vascular and neural injuries and limited function of the elbow joint. Anatomic reduction of broken ends,Kirschner wire internal fixation and early functional training are significant in the therapeutic efficacy of operation,and in the prevention or reduction of postoperative complications.
4.The systematic review on the appraisal research of the rationality of blood transfusion in some districts
Chinese Journal of Hospital Administration 2011;27(8):622-626
Objective To explore the rationality of clinical blood transfusion since the Ministry of Health enacted the The Technical Criterion of Clinic Blood Transfusion' in 2000. Methods Retrieved the literatures on the appraisal of rationality of clinic blood transfusion published in core journal between 2000 and 2010, and analyzed the rationality of clinical blood transfusion in recent 10 years. Results In 35 literatures entered, the proportion of appropriate blood transfusion of platelet was the highest compaved with the lowest proportion of plasma. the proportion of appropriate blood transfusion in operational department is higher than that in non-operational department. The primary reason of inappropriate blood transfusion is transfusion without indications. Conclusion The proportion of appropriate blood transfusion in china is low. The government should enhance the regulation of blood usage,and the public should he educated to realize the importarce of appropriote blood transfusion in order to promote it to develop healthily.
5.The exploratory development of mental intervention combined with simple brachial plexus anesthesia in children'upper extremity operation
Qinquan JI ; Biao JIANG ; Hongwei LIN
Chinese Journal of Primary Medicine and Pharmacy 2011;18(5):610-611
Objective To evaluate the effect of mental intervention combined with simple brachial plexus anesthesia in children' upper extremity operation. Method 80 cases of8 ~ 12 years old children were selected after strict evaluation and screening,of who needed upper extremity operation(fractures internal fixation not included) ,and the surgery time less than 120 minutes. All the operations were completed under the simple brachial plexus anesthesia, and combined with mental intervention preoperatively and intraoperatively. The changes of HR and BP intraoperatively the psyche condition after the operation completed were observed and followed up the mental change postoperatively. Result All the operation were completed. The HR and BP were stable intraoperation (P > 0. 05), the psyche was quiet after the operation completed,and no mental disorder was happened postoperative. Conclusion The mental intervention combined with simple brachial plexus anesthesia was safe in 8 ~ 12 years old children' upper extremity operation, and it deserved to spread and apply.
6.Advanced cholangiocarcinoma treated with gemcitabine combined with 5-FU: An initial study of short-term therapeutic effect
Mei WANG ; Biao GONG ; Bin JIANG
China Oncology 2001;0(03):-
Purpose:To observe the therapeutic effect of gemcitabine combined with 5-FU for the treatment of advanced cholangiocarcinoma. Methods:21 patients were given gemcitabine and 5-FU intravenously. Results:There was no complete response .The partial response rate was 23.8% and SD,38.1%.12 patients(57.14%) had amelioration of pain and improvement in quality of life.The toxicity was low and tolerable. Conclusions:Gemcitabine combined with 5-FU was an effective and safe regimen for treating advanced cholangiocarcinoma and worthy of further evaluation.
8.Studding Effect of Acupuncturing Baihui Point for Brain Function with fMRI Method
Huade CHEN ; Guanglei YING ; Biao JIANG
Journal of Zhejiang Chinese Medical University 2006;0(06):-
0.8). (2) The range of correlation coefficient of increasing regions is from 0.7 to 0.98. Time-course graph shows that the figure of most curve is like “”. [Conclusion](1) The function of puncturing Baihui may be connected with signal changes of corresponding brain areas. (2) fMRI is a feasible method on studying the mechanisms of acupunctrue.
9.The preliminary report of the device and clinical application of continu ous and constant pressure skin expansion perfusion apparatus(CCPSEPA)
Zhongwen HE ; Biao WANG ; Jiang LI
Chinese Journal of Medical Aesthetics and Cosmetology 2001;7(2):69-71
Objective To search for a simple and rapid skin expansion. Methods CCPSEPA-A kind of mutual feedback type continuous normal saline perfusion system was assembled with the use of conventional transfusi on apparatus, sphygmomanometer, three-way stopcocks, plasma bag etc.14 cases ( 17 expanders) were carried out with such a device, controlled by patients themselves. Results The volume of expanders was 50~300 ml and the duration of expansion was 7~14 days. All the cases proved a wonderful effect that the expansion was finished by only one or two times of water filling of storage water bag, and without any complications.Conclusion CCPSEPA is a new skin expansion apparatus of new type and practical ,simple and low price .The general goal of safe,simple, rapid and useful was realized basically by the device,and worth popularizing.
10.Protective effects of desflurane preconditioning against neutrophil -mediated anoxia / reoxygenation injury to isolated myocytes
Biao ZHU ; Zhanggang XUE ; Hao JIANG
Chinese Journal of Anesthesiology 1994;0(04):-
Objective Neutrophils (PMNs) play an important role in the myocardial injury-induced by ischemia/reperfusion. The purpose of the study was to assess the role of PMN in anoxia/reoxygenation (A/R) injury to primary cultured myocytes and the protective effects of desflurane preconditioning (DPC) .Methods Myocytes obtained from ventricle were cultured in MEM medium for 3 days. The cultured myocytes were then randomly divided into 4 groups : group Ⅰ A/R; group Ⅱ PMNs + A/R; group Ⅲ DPC + A/R and group Ⅳ DPC + PMNs + A/ R. In all four groups the cultured myocytes were subjected to anoxia by being incubated in a tightly closed incubator filled with 95 % N2 + 5 % CO, for 2 h, followed by one hour reoxygenation (95 % O2 + 5 % CO2). In group Ⅱ and Ⅳ 5.0 ? 106 ml -1 PMNs isolated from peripheral blood or bone marrow were added to the medium during the one hour reoxygenation. In group Ⅲ and Ⅳ the myocytes were exposed to 9 % desflurane for 1 h before A/R. The activities of lactic dehydrogenase (LDH) and creatine kinase (CK) and the concentration of cardiac troponin (cTnT) in the supernatant were measured before and at the end of the experiment. Cell survival rate, beating rate and arrhythmia rate of the cultured myocytes were also calculated under phase-contrast microscope before and at the end of the experiment.Results A/R caused significant increase in LDH and CK-MB activities, cTnT concentration and arrhythmia rates and decrease in beating rates except in group Ⅲ . The differences in LDH, CK-MB activities and arrhythmia rates between the baseline value and the value obtained at the end of the experiment were significantly lower in group Ⅳ than those in group D but still higher than those in group Ⅰ . The cell survival rate was significantly higher in group Ⅳ than that in grorp Ⅱ . Conclusion Neutrophil accentuates A/R injury while desflurane preconditioning attenuates neutrophil-mediated A/R injury to primary cultured myocytes.