Objective To observe the therapeutic effect of Bushen Tongluo Pill (Pills for reinforcing kidney and removing obstruction of meridians) on rheumatoid arthritis (RA).Methods Totally 100 RA patients were randomized into treatment group and control group with 50 cases in each group.The treatment group (50 cases) was administered Bushen Tongluo Pill and the control group (50 cases) was prescribed Celecoxib capsules and Methotrexate tablets for 3 months.The changes after treatment in the clinical symptoms including joint pain,swelling,joint functions,hand grip strength,and in the laboratory indices including erythrocyte sedimentation rate (ESR),rheumatoid factors (RF),and C-reactive protein (CRP),and the untoward effect as well were observed.Results The total effective rate of the treatment group was higher than that of the control (P0.05).Conclusion Bushen Tongluo Pill is effective for RA,the effect was superior to that of Celecoxib capsules and Methotrexate tablets.

Objective To investigate the expression and significance of TLR-2 and HO-1 in recurrent nasal polyps,and to discuss the relationship between the expression and the recurrence of nasal polyps. Methods The immune protein imprinting technology was used to detect the protein expression of TLR-2 and HO-1 in 20 cases of recurrent nasal polyps,20 cases of nasal polyps and 20 cases of normal mucosal tissue in control group, and the relationship between the two proteins were analyzed. Results Expression levels of TLR-2 and HO-1 in the tissues of the recurrent nasal polyps had statistically significant difference with nasal polyps group ( <0.05) . Expression levels of TLR-2 and HO-1 in the tissues of the nasal polyps had statistically significant difference with normal nasal mucosa tissues ( <0.05) .The expression of TLR-2 and HO-1 had significant correlation in each group ( <0.05) .Conclusion TLR-2 and HO-1 plays an important role in the recurrence mechanism of nasal polyps, and both of them may be as objective indicators for postoperative follow-up of patients with recurrent nasal polyps and judging the recurrent trend.

AIM: To determine whether vasorelaxation induced by cAMP is dependent on eNOS activation.METHODS: A constant perfusion model of rabbit femoral artery was used to observe the changes of perfusion pressure before and after intra-arterial infusing different concentrations of dbcAMP(a membrane-permeable cAMP analogue) or forskolin(a direct stimulator of adenyl cyclase) and the effects of NOS inhibitor L-NAME on their actions.RESULTS: Both dbcAMP and forskolin induced concentration-dependent relaxation of rabbit femoral artery bed and NOS inhibitor L-NAME partly inhibited this vasorelaxation.CONCLUSION: Vasorelaxation induced by cAMP is mediated partly through eNOS activation.

Objective To study the clinical characteristics in young women with breast cancer.Methods Clinical data on 71 young breast cancer cases (under 35 years) out of a total 810 female cases during a period of 20 years were retrospectively analyzed. Result Delayed medical consultation was more often seen in young patients(56?4)?d vs (35?3)?d; u=2.33; P

Objective: To establish the fingerprint of Moutan Cortex by HPLC. Methods: The chromatographic fingerprint was obtained with Dikma Diamonsil C18 column (250 mm × 4.6 mm, 5 μm) and gradient eluted with acetonitrile and water (with 0.085% phosphoric acid). The column temperature was maintained at 35 °C, and the flow rate was 1 mL/min. The detection wavelength was 254 (0-21.5 min), 230 (21.5-45 min), and 254 nm (45-60 min). The injection volume was 20 μL. The peaks were identified by LC-MS/MS. Results: The method had good precision, stability, and repeatability. Eighteen chromatographic peaks among 20 common peaks were identified by LC-MS/MS. Ten batches of Moutan Cortex were determined, and the similarities were above 0.96.Conclusion: The study lays the foundation for the full quality evaluation of Moutan Cortex.

Objective　To investigate the importance of CT diagnosis and differential diagnosis in Wilms′ tumors of children.Methods　45 cases of Wilms′ tumors confirmed by clinical and pathology were retrospectively analyzed,CT characteristics of Wilms′ tumor,renal carcinoma(2 cases),renal rhabdomyosarcoma(1 case)in children were discussed.Results　Wilms' tumors appeared in solid masses in 34 cases (76%),cysticsolid masses in 9 cases(20%),cystic masses in 2 cases (4%),7 cases (15.6%)had thrombosis in renal vein or IVC.Renal carcinoma shared the same appearance with Wilms′ tumor in image.Rhabdoid tumor of kidney appeard as cystic-solid mass with lineal calcification and subcapsular fluid accumulation.Conclusion　Wilms′ tumor is the most popular malignant renal tumors in children.It is originate from renal parenchyma,and likely to invade renal pelvis.Hemorrhhage,necrosis or cystic formation in tumor is common.They are difficult to be distinguished from renal cell carcinomas in radiology.Rhabdoid tumor of kidney is rare and has characteristic features on CT.

Objective:To explore the changing tendency of IgG to coronavirus associated severe acute respiratory syndrome(SARS).Methods:Between 1 and 153 days after the onset of symptoms, the antibody IgG to SARS associated coronavirus were detected in 534 patients with SRAS by ELISA. 216 randomly selected people without SARS contact history and SARS symptoms were contrasted.Results:The positive rates of IgG between SARS patients and control group respectivel were 58 1%,0 5%.There is a statistical significance(P=0 000).Among SARS patients, the positive rates of IgG in 1～10 days,11～30 days,31～60 days,61～90 days,91～120 days,above 120 days and after the onset of symptoms respectively were 18 8%(3/16 cases),63 8%(37/58 cases),55 6%(30/54 cases),51 4%(71/138 cases),62 1%(159/256 cases),83 3%(10/12 cases).Conclusion:There are low positive rates of IgG in SARS patients in the first 10 days after onset of symptoms, and abruptly ascending positive rates of IgG in 11～30 days.The positive rates of IgG remains the high levels during 4th and 5th months.Further observation is essential to elucidating the duration of IgG.

Objective: To explore the application value of ablation catheter for pacemaker atrial lead restoration in relevant patients.
Methods: A total of 6 patients with atrial lead dislodgement after pacemaker implantation were selected for our study. The atrial lead restoration was conducted by using ablation catheter via femoral vein pathway.
Results: The average operational time was (15.0 ± 3.7) min which was obviously less than traditional operational time. The position of electrode restoration was ideal with well immobilization.
Conclusion: Ablation catheter is feasible for arial lead restoration in patients with atrial lead dislodgement after pacemaker implantation.

OBJECTIVE: To research the correlation between development of sphenoid sinus and age in normal children and adolescents by 3-D CT images. METHOD: Review of CT images of the skulls of 120 children and adolescents aged 0~20 years old. They were divided into five groups. Then reconstructed 3-D shape of the sphenoid sinus, and measureed the maximal anteroposterior diameter, longitudinal diameter, and transverse diameter of the bilateral sphenoid sinus by the 2-D and 3-D approach respectively, then process statistical analysis. RESULT: Pearson analyses revealed a positive correlation between various diameters of sphenoid sinus measured by 2-D and 3-D approach and age (P<0. 05). CONCLUSION The development of sphenoid sinus has a linear correlation with age, and increases with age and growth in Yunnan region. It helps to know the three-dimensional CT images of the sphenoid sinus in children and adolescents by Simplant software, thereby allow the clinicians to understand the current situation of the development of sphenoid sinus. Meanwhile, it contributes to preoperative evaluation of sinus problems.
Adolescent ; Child ; Child, Preschool ; China ; Humans ; Image Processing, Computer-Assisted ; Imaging, Three-Dimensional ; Infant ; Infant, Newborn ; Skull ; Software ; Sphenoid Sinus ; growth & development ; surgery ; Young Adult

Animals ; Cyanides ; toxicity ; Mice ; Random Allocation ; Toxicity Tests, Chronic