1.FREE SKIN GRAFTING WITH FIBRIN ABHESIVE: CLNICAL AND HISTOPATHOLOGIC REVIEWS
Seung Ki MIN ; Kook Beum JIN ; Moon Jeong KANG
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1999;21(1):81-88
Adhesives
;
Burns
;
Calcium Chloride
;
Cicatrix
;
Cicatrix, Hypertrophic
;
Collagen
;
Factor XIII
;
Fibrin Tissue Adhesive
;
Fibrin
;
Fibrinogen
;
Follow-Up Studies
;
Gingiva
;
Hemorrhage
;
Humans
;
Mouth
;
Nose
;
Polymers
;
Skin Transplantation
;
Skin
;
Surgery, Oral
;
Sutures
;
Thrombin
;
Tissue Donors
;
Transplants
;
Wound Healing
2.Repeatability and Agreement of Macular Thickness Measurement Using Time and Spectral Domain OCT in Diabetic Macular Edema.
Se Beum OH ; Jun Woong MOON ; Hyung Chan KIM
Journal of the Korean Ophthalmological Society 2010;51(3):372-378
PURPOSE: To evaluate the repeatability of macular thickness measurements using time domain (TD) OCT and spectral domain (SD) OCT in diabetic macular edema. METHODS: In 42 eyes of 42 patients with diabetic macular edema, three consecutive macular measurements were performed with TD OCT and SD OCT, and measurements for macular thickness and total macular volume obtained by the two OCTs were compared. The within-subject standard deviation (Sw), coefficient of variation (CVw), and intraclass correlation coefficient (ICC) were calculated to assess repeatability, with agreement between measurements assessed with Bland Altman plots. The correlations were also evaluated via the Pearson's correlation coefficient. RESULTS: The Sw of TD OCT and SD OCT for foveal thickness, total macular volume were 29.67 micrometer/16.44 micrometer, 1.26 mm3/0.23 mm3, respectively, and were significantly lower in SD OCT. The ranges of the respective CVw and ICC values were 1.10-2.78%, 0.78~0.96 for TD OCT, and 0.29~0.94%, 0.92~0.99 for SD OCT. The SD OCT showed better repeatability for macular thickness measurements (all p< or =0.001). The 95% limits of agreement for foveal and total macular volume were 88.9 micrometer, 2.4 mm3, respectively. The Pearson's correlation coefficients of macular thickness and total macular volume between the two OCT methods were statistically significant (p=0.88-0.99). CONCLUSIONS: Although both OCTs proved reliable for macular thickness measurements in diabetic macular edema, SD OCT shows better repeatability than TD OCT. Although macular thickness measurements obtained from the two OCTs cannot be used interchangeably, there were statistically significant correlations between measurements obtained using the two OCTs.
Eye
;
Humans
;
Macular Edema
3.Comparison of Effects of Intravitreal Triamcinolone and Bevacizumab in the Treatment of Diabetic Macular Edema.
Se Beum OH ; Jun Woong MOON ; Hyung Chan KIM
Journal of the Korean Ophthalmological Society 2009;50(8):1190-1196
PURPOSE: To compare the effect of an intravitreal injection of triamcinolone acetonide with bevacizumab in the treatment of diabetic macular edema (DME). METHODS: For this study, the medical records of patients with diabetic macular edema, who received intravitreal triamcinolone injection (IVTA) or intravitreal bevacizumab injection (IVB), were reviewed. Best corrected visual acuity (BCVA), central macular thickness (CMT) and total macular volume (TMV) were evaluated before injection and at 1 week, 1 month, 2 months, 3 months, and 6 months after injection. The adverse events, such as increased intraocular pressure, and progression of cataract, were also reviewed. RESULTS: A total of 72 eyes from 72 patients, (IVTA: 40 eyes, IVB: 32 eyes) were included in this study. In the IVTA group, BCVA improved significantly at 1 week after injection and was maintained until 3 months after injection. In the IVB group, BCVA improved significantly at 1 week after injection and was maintained until 2 months after injection. In the IVTA group, CMT and TMV decreased significantly at 1 week after injection and were maintained until 3 months after injection, while in the IVB group CMT and TMV were maintained until 2 months after injection. The IVTA group showed significantly better results in visual improvement, CMT and TMV reduction compared to the results of the IVB group, from 1 month to 3 months after injection. In the IVTA group, intraocular pressure increased to more than 25 mmHg in 12.5% of patients during the follow-up period. CONCLUSIONS: While the functional and anatomical improvements are achieved by both IVTA and IVB for diabetic macular edema, the effect of IVTA is more prominent with longer duration than IVB.
Antibodies, Monoclonal, Humanized
;
Cataract
;
Eye
;
Follow-Up Studies
;
Humans
;
Intraocular Pressure
;
Intravitreal Injections
;
Macular Edema
;
Medical Records
;
Triamcinolone
;
Triamcinolone Acetonide
;
Visual Acuity
;
Bevacizumab
4.Comparison of Effects of Intravitreal Triamcinolone and Bevacizumab in the Treatment of Diabetic Macular Edema.
Se Beum OH ; Jun Woong MOON ; Hyung Chan KIM
Journal of the Korean Ophthalmological Society 2009;50(8):1190-1196
PURPOSE: To compare the effect of an intravitreal injection of triamcinolone acetonide with bevacizumab in the treatment of diabetic macular edema (DME). METHODS: For this study, the medical records of patients with diabetic macular edema, who received intravitreal triamcinolone injection (IVTA) or intravitreal bevacizumab injection (IVB), were reviewed. Best corrected visual acuity (BCVA), central macular thickness (CMT) and total macular volume (TMV) were evaluated before injection and at 1 week, 1 month, 2 months, 3 months, and 6 months after injection. The adverse events, such as increased intraocular pressure, and progression of cataract, were also reviewed. RESULTS: A total of 72 eyes from 72 patients, (IVTA: 40 eyes, IVB: 32 eyes) were included in this study. In the IVTA group, BCVA improved significantly at 1 week after injection and was maintained until 3 months after injection. In the IVB group, BCVA improved significantly at 1 week after injection and was maintained until 2 months after injection. In the IVTA group, CMT and TMV decreased significantly at 1 week after injection and were maintained until 3 months after injection, while in the IVB group CMT and TMV were maintained until 2 months after injection. The IVTA group showed significantly better results in visual improvement, CMT and TMV reduction compared to the results of the IVB group, from 1 month to 3 months after injection. In the IVTA group, intraocular pressure increased to more than 25 mmHg in 12.5% of patients during the follow-up period. CONCLUSIONS: While the functional and anatomical improvements are achieved by both IVTA and IVB for diabetic macular edema, the effect of IVTA is more prominent with longer duration than IVB.
Antibodies, Monoclonal, Humanized
;
Cataract
;
Eye
;
Follow-Up Studies
;
Humans
;
Intraocular Pressure
;
Intravitreal Injections
;
Macular Edema
;
Medical Records
;
Triamcinolone
;
Triamcinolone Acetonide
;
Visual Acuity
;
Bevacizumab
5.Gallbladder contractability before and after extracorporeal shock- wave lithotripsy.
Yoon Jin OH ; Jong Kyung MOON ; Young Goo KIM ; Hyung Jin SHIM ; Jong Beum LEE ; Kun Sang KIM
Journal of the Korean Radiological Society 1991;27(6):832-836
No abstract available.
Gallbladder*
;
Lithotripsy*
6.Cerbral Vasculitis in Rheumatoid Arthritis.
Yong Jae KIM ; Kwang Soo LEE ; Yeong In KIM ; Beum Saeng KIM ; Moon Chan KIM ; Ki Hwa YANG
Journal of the Korean Neurological Association 1994;12(4):804-808
No abstract available.
Arthritis, Rheumatoid*
;
Vasculitis*
7.Human Umbilical Cord Blood Mononuclear Cell Transplantation in Rats with Intrinsic Sphincter Deficiency.
Joa Jin LIM ; Jin Beum JANG ; Ji Young KIM ; Sung Hwan MOON ; Chung No LEE ; Kyung Jin LEE
Journal of Korean Medical Science 2010;25(5):663-670
To evaluate the effectiveness of the human umbilical cord blood (HUCB) transplantation for the treatment of intrinsic sphincter deficiency (ISD), we analyzed the short term effects of HUCB mononuclear cell transplantation in rats with induced-ISD. ISD was induced in rats by electro-cauterization of periurethral soft tissue with HUCB mononuclear cell injection after 1 week. The sphincter function measured by mean leak point pressure was significantly improved in the experimental group compared to the control group at 4 weeks. (91.75+/-18.99 mmHg vs. 65.02+/-22.09 mmHg, P=0.001). Histologically, the sphincter muscle was restored without damage while in the control group it appeared markedly disrupted with atrophic muscle layers and collagen deposit. We identified injected HUCB cells in the tissue sections by Di-I signal and Prussian blue staining. HUCB mononuclear cell injection significantly improved urethral sphincter function, suggesting its potential efficacy in the treatment of ISD.
Animals
;
Cells, Cultured
;
Cord Blood Stem Cell Transplantation/*methods
;
Humans
;
Leukocytes, Mononuclear/*transplantation
;
Rats
;
Rats, Sprague-Dawley
;
Treatment Outcome
;
Urinary Incontinence, Stress/diagnosis/*physiopathology/*surgery
;
Urologic Surgical Procedures/*methods
8.Surgical Treatment of Syringomyelia Secondary to Tuberculous Meningitis: Report of 4 Cases.
Beum Ju JANG ; Eunshin HAAH ; Moon Pyo CHI ; Jae O KIM ; Jung Chul KIM
Journal of Korean Neurosurgical Society 1996;25(9):1905-1909
The authors report our recent experience with 4 cases of syringomyelia that had developed secondary to tuberculous meningitis. Three cases of syringomyelia were treated by syringoperitoneal shunt and 1 case, by syringosubarachnoid shunt. Postoperatively, upper and lower extremity pain that had persisted in all the patients was relieved in all the patients, but improvement in limb sensation was noted in only 1 case. Improvement in limb motor power was noted in 3 cases. The clinical presentation, surgical consideration, and pathogenesis of syringomyelia is discussed together with a review of the literature.
Extremities
;
Humans
;
Lower Extremity
;
Sensation
;
Syringomyelia*
;
Tuberculosis, Meningeal*
9.Surgical treatment of atricular node reentrant tachycardia-2 cases report.
Jeong Seob YOON ; Jong Beum KWEON ; Chi Kyung KIM ; Moon Sub KWACK ; Se Wha KIM ; Wook Sung CHUNG ; Soon Jo HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(5):403-408
No abstract available.
10.Comparative Analysis of the Expression of p53, Rb, PCNA in thc Gastric Carcinoma.
Soong LEE ; Beum MOON ; Sung Kyu CHOI ; Chong Sun REW ; Chong Mann YOON ; Chang Soo PARK
Korean Journal of Medicine 1997;52(6):846-857
OBJECTIVES: Recently, the studies for oncogene and tumor marker have been actively performed to investigate the carcinogenesis of gastric carcinoma, but it is not clearly understood. We investigated the expression of tumor suppressor gene and proliferation activity in gastric carcinoma. METHODS: Immunohistochemistry for p53 protein (wild and mutant type), retinoblastoma protein(wild type), and PCNA was performed in 131 cases of formalin fixed paraffin embedded tissue sections of gastric carcinoma. We compared that expression with tissue invasiveness, lymph node metastasis, staging and, Lauren classification, and that expression with each other. RESULTS: 1) The positive ratio of p53 protein, Rb protein, also PCNA in gastric carcinoma was 64.9%, 98.5%, 99.2%, 2) The expression of p53 protein was related to invasiveness, lymph node metastasis, staging, and Lauren classification(p<0.05). 3) The positive reaction for Rb gene was identified in tumor cells as well as proliferating cells. 4) There was a close relationship between Rb gene expression and PCNA in gastric carcinoma (p<0.05). CONCLUSION: Theses results suggested that the expression of p53 gene is related to invasiveness, lymph node metastasis, staging and Lauren classification in gastric carcinoma. Expression of retinoblastoma gene is a closely related to proliferating activity.
Carcinogenesis
;
Classification
;
Dronabinol*
;
Formaldehyde
;
Genes, p53
;
Genes, Retinoblastoma
;
Genes, Tumor Suppressor
;
Immunohistochemistry
;
Lymph Nodes
;
Neoplasm Metastasis
;
Oncogenes
;
Paraffin
;
Proliferating Cell Nuclear Antigen*
;
Retinoblastoma
;
Retinoblastoma Protein