1.Clinics in diagnostic imaging (143). Perianal mucinous adenocarcinoma arising from chronic fistula-in-ano.
Chia Ming HO ; Cher Heng TAN ; Bernard Chi-Shern HO
Singapore medical journal 2012;53(12):843-quiz p. 849
We report a case of mucinous adenocarcinoma arising in the perianal soft tissue in association with chronic fistula-in-ano in a 43-year-old man who had a relapse of perianal pain and bloody discharge after six years of defaulted follow-up. He underwent magnetic resonance (MR) and computed tomography imaging with correct identification of the disease entity on imaging. Mesh-like septations and an enhancing solid component with high diffusion-weighted imaging (DWI) and intermediate apparent diffusion coefficient signals were observed. He underwent abdominoperineal resection of the tumour but succumbed due to postoperative complications. Literature on the MR imaging features of this tumour remains scarce. We highlight the MR imaging features, including those seen on DWI, which were useful in making the correct diagnosis. Though uncommon, this would be an important condition to recognise since assessment of fistula-in-ano by MR imaging is considered to be the standard of care in current clinical practice. The clinical features of this entity are also briefly discussed.
Adenocarcinoma, Mucinous
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complications
;
diagnosis
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Adult
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Anus Neoplasms
;
complications
;
diagnosis
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Chronic Disease
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Diagnosis, Differential
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Diffusion Magnetic Resonance Imaging
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Humans
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Male
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Rectal Fistula
;
complications
;
diagnosis
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Tomography, X-Ray Computed
2.Leiomyomatosis peritonealis disseminata presenting as omental torsion.
Chjoong Howe Alvin TAN ; Bernard Chi Shern HO ; Vishalkumar SHELAT ; Cher Heng TAN
Singapore medical journal 2012;53(4):e71-3
Leiomyomatosis peritonealis disseminata is usually asymptomatic or mimics widespread malignancy; acute presentation is rare. We describe a patient with right iliac fossa and lower abdominal pain. Two masses were detected via computed tomography, but at surgery, one of these implanted leiomyomas had undergone acute omental torsion. This case illustrates a rare complication of omental leiomyoma torsion clinically mimicking acute appendicitis.
Adult
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Diagnosis, Differential
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Female
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Humans
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Leiomyomatosis
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complications
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diagnosis
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Omentum
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pathology
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Peritoneal Neoplasms
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complications
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diagnosis
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Tomography Scanners, X-Ray Computed
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Torsion Abnormality
;
etiology
;
surgery
3.The therapeutic dilemma of idiopathic granulomatous mastitis.
Ee Ling Serene TANG ; Chi Shern Bernard HO ; Patrick Mun Yew CHAN ; Juliana Jia Chuan CHEN ; Mui Heng GOH ; Ern Yu TAN
Annals of the Academy of Medicine, Singapore 2021;50(8):598-605
INTRODUCTION:
Idiopathic granulomatous mastitis (IGM) is a rare, benign, chronic breast condition that can cause repeated abscesses or mass formation in bilateral breasts. The condition can severely impact the quality of life of affected women. This study aims to evaluate effective treatment modalities, as well as understand the demographics and clinical presentation of patients with IGM.
METHODS:
An 11-year retrospective review was performed of patients diagnosed with IGM from 1 January 2008 to 31 December 2018 at a tertiary breast unit.
RESULTS:
A total of 77 patients were included in the study. The median age at presentation was 36 years old. IGM presented most commonly as a breast lump (98.1%). The median number of flares was 2 (1-12). Of the 77 patients, 68.8% (53) were treated with antibiotics, 50.6% (39) with steroids, and 44.2% (34) underwent surgery, in the course of their IGM treatment. Forty-five (59.2%) of the 76 patients with IGM required a multimodal treatment approach to achieve remission. There was no significant difference in the number of flares no matter the initial treatment (
CONCLUSION
IGM is a clinical diagnosis. It is a rare, relapsing breast inflammatory condition that affects young females with no superior treatment modality. Smoking is associated with higher number of flares of IGM and should be discouraged in IGM patients.
Adult
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Anti-Bacterial Agents/therapeutic use*
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Female
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Granulomatous Mastitis/therapy*
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Humans
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Quality of Life
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Retrospective Studies
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Treatment Outcome
4.Multimodality imaging of splenic sclerosing angiomatoid nodular transformation.
Hock Tai Gavin LIM ; Cher Heng TAN ; Li Tserng TEO ; Chi Shern Bernard HO
Singapore medical journal 2015;56(6):e96-9
Sclerosing angiomatoid nodular transformation (SANT) is an exceedingly rare, benign and proliferative vascular lesion that arises from the splenic red pulp. It is often an incidental finding on imaging. The diagnosis of SANT is confirmed via histopathological examination of the resected spleen. Herein, we present a case of SANT and describe its typical imaging characteristics. An asymptomatic 39-year-old man was found to have a 3.1 cm × 2.7 cm × 2.3 cm hypoechoic splenic lesion during abdominal ultrasonography, which was performed to investigate his elevated gamma-glutamyl transpeptidase and alanine transaminase levels. Contrast-enhanced computed tomography suggested a vascular splenic lesion, while magnetic resonance imaging demonstrated features consistent with SANT. In view of the increasing size of the lesion on follow-up imaging, the patient elected for splenectomy. Histopathological examination confirmed SANT, and the lesion was completely resected by laparoscopic splenectomy.
Adult
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Alanine Transaminase
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blood
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Cell Proliferation
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Contrast Media
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chemistry
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Disease Progression
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Humans
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Image Processing, Computer-Assisted
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methods
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Incidental Findings
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Laparoscopy
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Magnetic Resonance Imaging
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Male
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Multimodal Imaging
;
methods
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Spleen
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diagnostic imaging
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Splenectomy
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Splenic Diseases
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diagnostic imaging
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Tomography, X-Ray Computed
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Ultrasonography
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gamma-Glutamyltransferase
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blood