Scleredema is a rare connective tissue disease of unknown etiology and characterized by non-pitting thickening of subcutaneous tissue of the neck, face, head, upper trunk and arms. We present a 28 year-old man with extensive skin changes following upper respiratory infection, who have not any concurrent disorders such as diabetes mellitus. Histopathological findings of skin showed normal epidermis with a widening of spaces between collagen bundles by infiltration of acid mucopolysaccharide in the dermis.
Adult ; Arm ; Collagen ; Connective Tissue Diseases ; Dermis ; Diabetes Mellitus ; Epidermis ; Head ; Humans ; Neck ; Scleredema Adultorum* ; Skin ; Subcutaneous Tissue