Objective To investigate the current status of dialysis adequacy and pass rate of Kt/Vurea in peritoneal dialysis (PD) patients, and to explore the related risk factors and nursing intervention.Methods The participants referred to PD patients with adequate dialysis (≥3 months) and regular follow-up from August to December in 2015. The demographic data and clinical characteristics were collected according to questionnaire survey and laboratory examination. The participants were divided into two groups based on their KT/Vurea.Results Totals of 185 clinical stable PD patients were included in the study, with an average age of (56.41±14.57) years old and dialysis duration of (34.74±28.46) months. The cut-off of KT/Vurea was (2.05±0.50) and the pass rate of KT/Vurea was 77.84%. The passed participants tended to be females and had lower BMI and better residual renal function compared with participants who failed KT/ Vurea (P＜0.05). No significant difference was found in age, blood pressure, blood calcium, phosphorus, PTH, hemoglobin, blood albumin, alkaline phosphatase,CRP,Vitamin D, dialysis duration,and dialysis dose (P＞0.05). Logistic regression analysis indicated that sex and residual renal function were independent factors for Kt/Vurea. Being females was a protective factor. Decreased KT/Vurea, higher calcium-phosphorus product, lower serum albumin, prolonged dialysis time and increased dialysis dose were independent risk factors of residual renal function. Conclusions Sex and residual renal function were independent factors for Kt/Vurea. Nursing intervention should be focused on diet control and regular follow-up to prevent the progress of residual renal function and the improvement of dialysis adequacy.

Objective:To retrieve, evaluate and integrate the best evidence of home exercise rehabilitation for peritoneal dialysis patients, so as to provide basis for formulating home exercise rehabilitation plan for peritoneal dialysis patients.Methods:Evidence-based problems were constructed according to the PICO (population, intervention, control and outcome) principle. The home exercise rehabilitation guideline, expert consensus, evidence summary, systematic review, and randomized controlled trial of peritoneal dialysis patients were systematically searched in the evidence-based resource databases such as UpToDate, British Medical Journal (BMJ) Best Practice, Guidelines International Network, and in the comprehensive databases such as PubMed, Embase, and Web of Science. The retrieval time limit was from the establishment of the database to November 20, 2021. Two researchers with evidence-based knowledge independently evaluated the quality of the article and the level of evidence.Results:A total of 10 articles were included, including one evidence summary, one practical suggestion, one expert consensus, two systematic reviews, and five randomized controlled trials. A total of 24 best evidences were summarized from 8 aspects, including applicable population, starting time, exercise evaluation, exercise prescription formulation, exercise type, exercise frequency and duration, exercise intensity and exercise precautions.Conclusions:The best evidence of home exercise rehabilitation for peritoneal dialysis patients provides a certain evidence-based basis for the selection of home exercise rehabilitation programs for peritoneal dialysis patients.

Objectives:To investigate the risk factors of sarcopenia in patients receiving maintenance peritoneal dialysis (MPD).Methods:One hundred and thirteen patients receiving maintenance MPD for ≥3 months during January and December 2017 were enrolled in this study. According to the Asian Working Group for Sarcopenia(AWGS)algorithm, there were 26 patients with sarcopenia accounting for 23.0% of all MPD patients. Demographic and anthropometric data were collected; laboratory tests were conducted, Kt/V urea and normalized protein equivalent of total nitrogen appearance were calculated; the bioelectrical impedance analysis (BIA) was performed and grip strength was tested. The nutritional status was evaluated with Subjective Global Assessment (SGA). Logistic regression was used to analyze the risk factors of sarcopenia in MPD patients. Results:BMI and dialysis dose of patients with sarcopenia were significantly lower than those without sarcopenia [(20.35±2.35) kg/m 2vs. (23.81±3.14) kg/m 2, t=-5.181, P<0.01; (5.57±1.83) L/d vs. (6.66±1.71) L/d, t=-2.795, P<0.01]. The bioelectrical impedance analysis showed that the total water content of patients with sarcopenia was higher than that of patients without sarcopenia [(35.44±6.40) kg vs. (28.52±4.89) kg, t=5.077, P<0.01]; while the protein content[(7.46±1.31) kg vs. (9.24±1.63) kg, t=-5.080, P<0.01] and skeletal muscle content [(20.54±4.18) kg vs. (25.88±4.95) kg, t=-4.980, P<0.01] of patients with sarcopenia were lower than those without sarcopenia. Multivariate analysis showed that decreased BMI( OR=0.934, 95 %CI: 0.723-0.998, P<0.01) and body protein ( OR=0.927, 95 %CI: 0.698-0.996, P<0.01), increased total body water( OR=1.382, 95 %CI: 1.053-1.813, P=0.02) were independent risk factors for sarcopenia in MPD patients. Conclusion:The incidence of sarcopenia in MPD patients is high, which is associated with the excessive volume load and malnutrition of patients.