Objective To study the effect of Shenqi Fuzheng injection on immune function and quality of life in patients with advanced gastric cancer.Methods 100 Patients with advanced gastric cancer treated from July 2014 to April 2017 in our hospital were randomly divided into two groups.The patients in the control group were treated with conventional FOLTOX regimen.The patients in the experimental group received Shenqi Fuzheng injection.The immunological function and quality of life of the two groups were analyzed and analyzed.Results Compared with the control group, the content of CD3+ was significantly improved in the patients treated with Shenqi Fuzheng Injection, the content of CD8+ was effectively decreased and the CD4+ / CD8+ ratio was effectively improved.Shenqi Fuzheng injection can effectively improve the immune function of patients, the difference was statistically significant(P<0.01).The number of patients in the treatment group was 39, and the control group was 26, the difference was statistically significant(x2 =7.43, P<0.01).There were 40 patients with sleep improvement in the treatment group and 25 patients in the control group, the difference was statistically significant(x2 =9.89, P<0.01).Conclusion Applying Shenqi Fuzheng Injection on FOLTOX can effectively improve the immunity of patients and improve the quality of life.Shenqi Fuzheng injection in clinical worthy of promotion.