1.Effects of Naturenz - A natural compound on the health of patients exposed to A.O/Dioxin
Journal of Vietnamese Medicine 2003;284(5):34-37
Naturenz, a mixture of plant oxydase, protease, natural anti-oxydants, aminoacids and vitamins has been used for treating dioxin exposed patients. This preparation can improve the patients status. An icrease of SH-group, of total hem content and of anilin hydroxylase acitivty in blood, a decreasing of urine urobilinogen was notified on patients after administration
Dioxins
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Chemistry
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Poisons
2.Study on effects of PDP product (roborant drug) on experimental animals by some criteria of protein metabolism
Pharmaceutical Journal 2003;327(7):29-31
PDP has been verified to enforce the body’s immune system by improving both cellular immune and humour immune. Statistical analysis of blood cell quantity of rabbit before, during and after taking PDP showed that erythrocyte, leukocyte and platelet were proliferated significantly, especially leucocyte and platelet. G-globulin in the serum of white mouse tested by the dose of 5mg/10g and 10mg/10g of body weight has been found to increase significantly, the rate of albumin/globulin reduced. The same result also has been observed in the white sewer rat and rabbit. The effect of PDP on the grease was investigated on Tam hoang chicken. It was found that there was a reduction of the rate of the grease over body weight when the chicken was taken PDP. Electrocardiogram of rabbit serum, which was recorded at 2mV and 50cs/min proved that PDP did not cause any harmful effect on heart. Besides, no physical disease occurred on heart action
Pharmaceutical Preparations
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Animal Experimentation
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Animals
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drugs
3.Study on elaboration of method for evaluation of chitosan content in product of Pokysan demic cream
Pharmaceutical Journal 2003;325(5):24-25
One method to determine the content of chitosan present in Pokysan cream has been developed. Chitosan was separated from Pokysan by dissolving the cream in acidic solution, extracted by chemical mixtures of I and II, which were prepared by laboratory of polymers in medico – pharmacy, and then collecting the precipitate of chitosan in the alkaline medium. This precipitate was then qualified by Lugol reagent and IR spectra. Collected chitosan precipitate was also qualified and quantified. These results proved that chitosan has been included in Pokysan cream and our method is confident
Chitosan
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Evaluation Studies
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Laboratories
4.To evaluate the density on the upper part of femurs on elders by unigamma-plus
Journal of Practical Medicine 2005;505(3):35-37
A study on 90 people ( 62 male and 30 female) who had history of bone fracture due to serious trauma was conducted in Friendship Hospital. The result showed that: the age and BMI is equivalent between two groups. The bone mineral density in males is higher than that in females, the bone mineral density is highest on neck of femur and lowest on trochiter. The rate of osteomalacia on the upper part of femur was 31.5%. The density of the neck of femur in male group is higher than female ones. Weight, BMI and sport playing are factors related to crease bone density. Age, smoking and alcohol drinking are factors that lessen the bone density. For the elders, it is nesesay to measure the bone density in order to have preventive methods and appropriate treatment, avoid bone facture later.
Femur
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Aged
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Bone Density
5.Effects of Camellia sinensis Leaf Extract on Dental Caries Causing Streptococcus mutans
Journal of Medicinal Materials - Hanoi 2003;8(4):110-114
Previous papers have reported that polyphenols from green tea (Camelia sinensis L.) were useful for controlling dental caries. This study examined the effects of the ethanol total polyphenol extract (CX) of green tea leaves on dental caries causing Streptococcus mutans. CX showed to inhibit the glycolysis, biofilm formation and respiration of S. mutans. At the concentration of 0.05%, CX suppressed 30% oxygen consumption in glucose excessive medium, totally inhibited NADH oxidase activity and killed the bacteria with D value of about 13 minutes. The combination of 0.025% CX and 0.25 mM NaF blocked pH drop during glycolysis. Polyphenols from green tea leaves inhibited therefore the adherence of S. mutans in vitro and proved to be effective against dental caries.
Tea
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Plants
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Biochemistry
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Dental Caries
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Streptococcus mutans
6.Vaginal misoprostol versus extra amniotic balloon for second trimester induced abortion
Ho Chi Minh city Medical Association 2005;10(1):13-16
The study was carried out at Hung Vuong Hospital in 1998 to compare vaginal misoprostol with extra-amniotic balloon to induce abortion in second trimester. Patients were received either 800mcg misoprostol vaginally (n=87) or 500ml of 0.9% NaCl solution inserted into extra-amniotic cavity (n= 93) for induced abortion. Vaginal misoprostol was repeated 24-hourly for maximum of three times. The abortion rates were 98.9% and 96.8% for misoprostol and balloon group, respectively. A second attempt was need in approximate one third of patients in misoprostol group and 10% in balloon group. Side effects of misoprostol were mild and transient. Vaginal misoprostol is as effective as balloon for induced abortion in second trimester. Misoprostol is cheap and easily stored and used. Vaginal misoprostol could be considered as an alternative to balloon for induced abortion
Abortion, Therapeutic
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Misoprostol
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Abortion, Induced
7.Filariasis mosquitoes and susceptibility of Cx.quinquefasciatus and Cx.vishnui to insecticides in the endemic area of Wurchereria bancropti filariasis
Journal of Malaria and parasite diseases Control 2003;0(6):42-48
Filariasis mosquitoes and susceptibility of Cx. quinquefasciatus and Cx. vishnui to insecticides were investigated in September 2004 and May 2005 in Khanh Trung commune, Khanh Vinh district, Khanh Hoa province. Twenty two mosquito species belonging to 5 genus have been found, of which the primary vector of W.bancrofti filariasis was captured with a high density, while vectors of B.malayi was found in a lower density. A total of 805 mosquitoes of 6 species (An.barbumbrosus, An. vagus, Cx.fuscocephala, Cx.quinquefasciatus, Cx.tritaeniorhynchus and Cx. vishnui) were dissected. None of them were positive with microfilaria. Cx.quinquefasciatus was found highly resistant to lambdacyhalothrin, alphacypermethrin and malathion with the mortalities of 11 %, 21%, and 60%, respectively. Similarly, the mortalities of Cx.vishnui were 19.76%, 23.83% and 13%-17%, respectively.
Filariasis
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Culicidae
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Malaria
8.Ability of Bacillus subtilis for treatment of rhinosinusitis in a murine model
Journal Ho Chi Minh Medical 2005;9(4):215-219
Probiotic preparations of Bacillus subtilis (B. subtilis) have been used by humans to treat and prevent the common forms of diarrhea caused by bacteria and virus, as well as other infections. To develop preparations of B. subtilis as an intranasal form, the authors studied the persistence and the antirhinopharyngitis of B. subtilis given nasally to mice. Substantial numbers of B. subtilis were still present in the nasopharynx 6 days after inoculation. The reduction in bacterial growth was similar to the positive controls. Also a reduced histopathological score was evident in corresponding with treating by ampicillin and prednisolone. Specifically, the authors obtained superior results in mice having administration of a dose of B. subtilis a day before inoculation of S. pneumoniae
Sinusitis
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Bacillus subtilis
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Therapeutics
9.A method for determination of trace content of protein in material of chitin/chitosan
Pharmaceutical Journal 2002;319(11):23-24
Protein trace present in chitin/chitosan product has been determined by our proposed method in which protein trace included in chitin/chitosan was extracted by refraction in 10% NaOH solution at 100oC for 5 hours. Chitin/Chitosan precipitate was discarded. protein trace in the solution was restored by neutralizing with HCl 10N to get the yellow powder. This powder was then analyzed for total nitrogen content by Kjeldahl method. The control method was conducted at the same procedure excepted from the presence of 10% NaOH. The results of different chitin/chitosan samples obtained from these two methods showed that amount of protein trace obtained from above proposed method was somewhat higher than that of the control one. Besides, the purified chitosan sample gave the lower protein trace content than that of the technical chitosan sample as well as chitin one. Protein trace bound between macromolecules of chitin/chitosan was separated in the proposed method by boiling water under alkaline condition whereas it was not completely separated in the control method because sodium hydroxide was absent.
Chitin
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Chitosan
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Proteins
10.Preliminary results of study on manufacture of biological polymeric membrane for the treatment of burns
Pharmaceutical Journal 1998;272(12):17-19
Biopolymeric membrane is made on the polysaccharide of natural origin according to our own technological process. It is a high bioactive, biocompatible, biodegradable polymeric membrane with effective action for treating wound healing. The preliminary results of clinical study suggested that the membrane were effectively used as biologic dressings for the treatment of donor sites of skin graft, partial thickness burns and granulation tissue. The wound surface after healing was smooth and flexible. The biopolymeric membrane is not only suitable for the treatment of burn wounds, but also it can applied for the skin surgery with excellent results.
burns
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therapeutics