1. Quantitative morphometry of the orbit in adults based on a three-dimensional reconstruction method
Bayasgalan P ; Lhamjav M ; Uranchimeg DU ; Uranchimeg DA
Innovation 2015;9(Ophthalmology):38-41
The stereo-structure of the orbit is affected by several orbital diseases, e.g. congenital orbital dysplasia, orbital fracture, and intraorbital tumor. The three-dimensional (3D) reconstruction technique serves as a practical tool in diagnosis, surgical planning, and outcome prediction of plastic and reconstructive surgery. In our study, the morphologic features of the Mongolianadult orbit were described by 11 anatomic parameters using a 3D reconstruction technique and quantitative morphometry. The morphologic parameters of orbit such as bony orbital volume, orbital foramen area and orbital rim perimeter were measured on 3D models using this technique. Three-dimensional (3D) reconstruction based on high-resolution spiral computed tomography (CT) scans has been used for more than 10 years to reveal the anatomic location and morphologic features of orbital abnormalities and plays a important role in diagnosis, surgicalplanning, and outcome prediction. The findings of the study would allow for quantification of the orbital features of Mongolian adults and provide parameters for preoperative planning and prediction of postoperative outcome.
2.Health risks of overweight and obesity among children
Otgonjargal D ; Bayasgalan J ; Anu P
Mongolian Medical Sciences 2023;203(1):53-58
:
Childhood obesity is, according to the WHO, one of the most serious challenges of the 21st century. More than 100 million children have obesity today. Globally, the prevalence of obesity and overweight tripled in the child and youth populations from the mid-1970s (about 4%) to 2016 (greater than 18%). In 2016, more than 330 million children and adolescents were affected by overweight or obesity globally. It is estimated that by 2030 nearly 30% of all children will be affected by overweight or obesity. For this reason, childhood obesity is a major public health problem worldwide.
This study summarizes and reviewed research findings related to childhood obesity and health risks. Overweight and obesity are defined as an abnormal or excessive accumulation of fat that can harm health. Obesity has a multifactorial origin that involves both genetic and environmental factors. Several studies showed that excess body fat increased the risk of multiple comorbidities, such as high blood pressure, coronary heart disease, type 2 diabetes, insulin resistance, and cancer. According to the results of the research, the mother's nutritional status and obesogenic environments have a great influence on childhood obesity. A summary of the results of many studies concluded that childhood obesity is more likely to develop non-communicable diseases in adulthood. The global prevalence of overweight in children aged 5 years or under has increased modestly, but with heterogeneous trends in low and middle-income regions, while the prevalence of obesity in children aged 2–4 years has increased moderately. Overweight or obesity during childhood has important short-term and long-term consequences.
Conclusion
In recent decades, the prevalence of obesity in children has increased dramatically. For the successful implementation of activities to prevent overweight and obesity in children, it is necessary to create a supportive environment and to promote health.
3.Body iron store and prevalence of iron deficiency In Mongolian children aged 6-59 months
Bolormaa N ; Bayasgalan J ; Batjargal J ; Enkhmyagmar D ; Oyundelger D ; Enkhtungalag B ; Munkhtstetseg P
Mongolian Medical Sciences 2020;192(2):18-26
Background:
Iron is an essential mineral needed for physical and cognitive development with iron needs greatest
during pregnancy, infancy, childhood, and adolescence. Iron is vital throughout the lifespan as it
is a component of haemoglobin, the protein responsible for transporting oxygen from the lungs to
body cells for energy production. Iron deficiency results from a depletion of body iron stores due to
increased iron needs, inadequate dietary iron intake, reduced iron absorption, or loss of iron from
infections caused by malaria, hookworms, and other intestinal parasites. In advanced stages, iron
deficiency leads to iron deficiency anaemia, a condition of low red blood cells and reduced oxygen-carrying capacity.
Goal:
This study aimed to determine body iron stores in Mongolian children aged 6-59 months, and estimate
prevalence of iron deficiency among of studied children.
Materials and Methods:
In this study were used materials that collected during the fifth national nutrition survey conducted
in 21 provinces of 4 economic regions and 8 districts of Ulaanbaatar city of Mongolia. The fifth
national nutrition survey was household based survey; therefore sampling unit was household
with 5 year-old child. We had used demographic information collected by interview methods and
laboratory examination results on ferritin, soluble transferrin (sTfR), C reactive protein (CRP) and
α1-acid glycoprotein (AFP) in serum samples collected from 6 to 59 months old children, pregnant
women and 15–49 year-old men living in child’s households. Serum Ferritin and soluble transferrin
(sTfR) were used as a biomarker for iron store and iron deficiency and C reactive protein (CRP)
and AFG were used as indicators for acute and chronic infection. The determination of iron status
is challenging when concomitant infection and inflammation are present because of confounding
effects of the acute-phase response on the interpretation of most iron indicators. Effects of C reactive
protein (CRP) and AGP concentrations on estimates of ID according to serum ferritin (SF) and soluble
transferrin receptor (sTfR) were considered in the study.
Ethical considerations :
The survey protocol was discussed at the scientific committee of the Public health institute and approved by director of scientific committee of PHI on June 28, 2016. Ethical approval for conducting
the survey, including obtaining biological samples was obtained from the Medical ethics committee
under the Ministry of Health of Mongolia on July 7, 2016. Participation in the survey was voluntary,
oral and written informed consent was obtained from each participants and adult caregivers of under
5 year-old children.
Results:
Biomarkers of iron status were adjusted with inflammation indicators and estimated iron deficiency
(ID) and total body iron store in 1732 children 6-59 month-olds. The study findings showed that
adjusted mean concentration of serum ferritin and soluble transferrin receptor was 33.7 µg/l and
8.8 mg/l in children age of 6-59 months, respectively. The calculated total body iron store by using
adjusted SF and soluble transferrin receptor was 2.8 mg/kg among surveyed children. Iron deficiency
was estimated by using 2 different biomarkers among selected population group. The prevalence of
iron deficiency estimated by using SF was 20.7% in children 6-59 months. Iron deficiency in children
defined by using serum soluble transferrin receptor was 27.7%.
Conclusions
1. The average serum ferritin and soluble transferrin receptor concentrations was 33.7 µg/l and 8.8
mg/l in children age of 6-59 months, respectively. Total body iron store estimated by using SF
and soluble transferrin was 2.8 mg/kg among surveyed children.
2. The prevalence of iron deficiency estimated by using SF and sTfR was 20.7% and 27.7% in
children 6-59 months, respectively. According to the WHO recommendation, prevalence of iron
deficiency among Mongolian children aged 6-59 months is classified as “prevalent”.
3. Overall proportion of children with low body iron store was 22.4%. The prevalence of iron
depletion is relatively common in boys, young children aged 6–23 months, and rural children
aged 6-59 months.