Objective: Retinal structural changes which were investigated by optical coherence tomography (OCT) have been reported in schizophrenia. Since cognitive dysfunction is a core feature of schizophrenia, the correlations between retinal findings and cognitive functions of patients and their healthy siblings may provide insight into the pathophysiological processes of the disorder. We aimed to investigate the relationship between neuropsychiatric tests and retinal changes in schizophrenia patients and their healthy siblings. Methods: We measured OCT parameters and cognitive performance (via Trail Making Tests, verbal fluency tests, and The Digit Span Tests) of 72 participants (36 patients with schizophrenia and 36 healthy siblings) and disease severity (with Positive and Negative Syndrome Scale, Global Assessment of Functioning, and Clinical Global Impression scales) in patients with schizophrenia and evaluated the relationship between retinal findings and clinical parameters, especially neurocognitive tests. Results: We found decreased ganglion cell layer-inner plexiform layer thickness and macular volume in the patient group. There were strong correlations between neurocognitive tests and OCT findings in both groups. On the other hand, there was not any correlation between retinal findings and disease parameters. Conclusion The cognitive symptoms of schizophrenia may be more closely related to structural changes in the retina.

Objective: Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients. Methods: This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form. Results: We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life. Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.

Objective: Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients. Methods: This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form. Results: We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life. Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.

Objective: Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients. Methods: This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form. Results: We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life. Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.

Objective: Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients. Methods: This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form. Results: We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life. Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.

Objective: Emotion regulation is an important skill to cultivate in patients with obsessive-compulsive disorder (OCD) for helping with the positive prognosis of their disease. Patients with OCD exhibit higher rates of impulsivity compared to healthy volunteers. According to previous studies, there is significant impairment in the quality of life in OCD. Despite their importance, no study has yet been conducted on the interrelation of these clinical parameters in OCD patients. We investigated the relationship between disease severity, emotional dysregulation, impulsivity, and quality of life in untreated OCD patients. Methods: This study included 40 untreated outpatients with a diagnosis of OCD. We applied the following form and scales: Sociodemographic and clinical data form, the Yale-Brown Obsessive Compulsive Scale, the Difficulties in Emotion Regulation Scale, the Barratt Impulsiveness Scale Short Form, and the World Health Organization Quality of Life Scale Short Form. Results: We found a positive relationship (p<0.001) between emotional dysregulation and impulsivity in OCD patients. A positive relationship (p=0.003) was identified between disease severity and emotional dysregulation, while an inverse relationship (p<0.001) was observed between disease severity and quality of life-psychological health. Increased impulsivity and emotional dysregulation were also associated with a deterioration in quality of life. Conclusion There is a significant positive relationship between emotional dysregulation and impulsivity in OCD patients. These clinical parameters may serve as important targets for treatment approaches in OCD patients and thus should be considered in the future work.