Even though the use and production of polychlorinated biphyls (PCBs) and organochlorine (OC) pesticides have been regulated worldwide, in agreement with the Stockholm convention in 2001, they are still posing serious environmental threat both to wildlife and humans. These lipophilic compounds, with high resistance to degradation and long half- lives in humans, have been confirmed to bioaccumulate in fatty tissues of biological specimens such as blood, breast milk, and adipose tissues through dietary intake. The analysis of these tissues reveals the rate of exposure and distribution in the environment.