1. Correlation between the blood glucose level and food consumption of Elder people
Ariunjargal Z ; Zesemdorj O ; Erdenebat N ; Odsuren S ; Bat-Erdene N ; Lkhagvasuren TS ; Munkhtsetseg J ; Munkhzol M ; Odkhuu E
Innovation 2014;8(2):28-32
The increasing proportions of aged persons have been accompanied in the world. NCDs are often associated with older age groups. High blood glucose levels and unhealthy diet increase the risk of or cause most NCDs. In this study we aimed to determine correlation between the older people (60<) blood glucose level and food consumption. 1563 healthy elder people participated in this research. We measured blood glucose level in all subjects at the Nursing school’s Training and Research Center of health science university of Mongolia. Ulaanbaatar city, Orkhon aimag, Khovd aimag, Khentii aimag, Bulgan aimag, Dornogovi aimag, Tov aimags represented urban areas, while the rest of aimags and soums represented rural areas. The questionnaire was used to collect data on respondent’s social-economic status, fruit and vegetable consumption, physical activity, and their causes. In order to assess the diet pattern of the surveyed population, the respondents were asked about frequency of fruit and vegetable consumption, type of oil used in food, and amount of salt consumed daily. Simple regression analysis was performed to shown that significantly positive correlations between blood glucose and salt intake (р<0.001), The other composition are no significantly changes.
2. Relationship between thyroid gland function and serum lipid level in elderly people
Odsuren S ; Bat-Erdene N ; Erdenebat N ; Zesemdorj O ; Odkhuu E ; Munkhtsetseg J ; Munkhtulg L ; Munkhzol М
Innovation 2013;7(1):48-51
Determine the pituitary thyroid gland axis function abnormalities and relate it with serum lipid level.We enrolled 313 elderly people from UB and Orkhon aimag. Serum total TSH, T3, T4 hormones, low –density lipoprotein, high-density lipoprotein, total cholesterol and triglyceride level were defined by ELISA and fully automatic analyzer. All analyses were conducted with the use of SPSS 19.0, MS Excel 2007 program in which mean variables, One way Anova test and bivariate correlations are included.A total of 313 elder subjects, male 29.4%, female 70.6% and mean age was 71.8±9.8. Pituitary thyroid hormone abnormalities were detected mostly in females (p=0.027), thyroid hormone decrease was noticed in 70-79 age. In all groups serum triglyceride level as in normal range but it was significantly high (p=0.027) in hypothyroid group. Triglyceride level was negatively correlated with total T4 (p<0.01), positively correlated with T3 (p<0.01).Thyroid hormone decrease increases serum lipid especially triglyceride level. Furthermore it increases atherosclerosis risk factor to elderly people thus affects the quality of life.
3. ATHEROGENIC DYSLIPIDEMIA IN MONGOLIAN OLDER PEOPLE
Oyunsuren M ; Odsuren S ; Erdenebat N ; Bat-Erdene N ; Zesemdorj O ; Odkhuu E ; Munkhzol M ; Lkhagvasuren TS
Innovation 2015;9(3):164-166
Atherogenic dyslipidemia comprises a triad of increased blood concentrations of small, dense low density lipoprotein (LDL) particles, decreased high-density lipoprotein (HDL) particles, and increased triglycerides. A typical feature of obesity, the metabolic syndrome, atherogenic dyslipidemia has emerged as an important risk factor for cardiovascular disease. We have determined levels of serum lipid profiles in 1861 older people who lives 5 regions in Mongolia. The concentrations of total cholesterol, triglycerides and high density lipoprotein cholesterol (HDL-C) were measured using a biochemical reagents by biochemical fully automated analyzer. The levels of LDL-C were calculated by the Friedewald equation. Overall prevalence of dyslipidemia was 4.3% in men and 3.0% in women. Logistic regression showed that Odds ratio of the atherogenic dyslipidemia was OR=1.3, p=0.001 (CI 95% 0.93-2.47) for body mass index, OR=1.6, p=0.02 (CI 95% 1.0-2.88) for waist circumference, OR=1.76, p=0.03 (CI 95% 1.12-3.54) for waist hip ratio. Odds ratio of the atherogenic dyslipidemia was OR=0.98, p=0.001 (CI 95% 0.34-1.05) for gender and OR=1.0 p=0.001 (CI 95% 0.65-1.03) for age. Overall, 3.3% of older people had atherogenic dyslipidemia and 4.3% of men and 3.0% of women had atherogenic dyslipidemia. An increase of physical parameters are getting a risk factor of atherogenic dyslipidemia.
4.Study Of Jur Ur – 4 Decoction Using Traditional Medical Sourcebooks
Anu A ; Oyuntsetseg N ; Bat-Erdene J
Journal of Oriental Medicine 2016;10(1):20-22
A diabetes is commensurate with the clinical symptoms to thirst
disease of Mongolian traditional
medicine when Jur ur-4 medicine is used. Jur ur – 4 is composed of
Gardenia jasminoides Ellis., Vitis
vinifera L., Coriandrum sativum L., and Gentiana acuta Michx. The
aim of this study is to analyze
components of Jur ur – 4 decoction by traditional methods. In
addition, each components of taste,
power and wisdom have compared to medicine indication. All of
components have cool power and
dispel bile heat. It has cool power and cure heat. The main
components are Vitis vinifera L., and
Coriandrum sativum L., cure thirst, Gardenia jasminoides Ellis., is
being detoxification and Gentiana
acuta Michx., is adjuvant that is used in bile heat for Jur ur-4
medicine.
5. The study of socioeconomic and geographical factors that affect healthy aging of Mongolians
Badrakh M ; Zesemdorj M ; Odsuren S ; Bat-Erdene N ; Ujin SH ; Delgerekh B ; Munkhtulga L ; Munkhtsetseg J ; Munkhzol M ; Lhkagvasuren L ; Khuderchuluun N ; Odkhuu E
Innovation 2015;9(4):65-69
As the proportion of aged population has been increasing worldwide by the rapid development of socio-economy, health science, and educational level that affect the policy against health service and social welfare, one of the urgent issues of Mongolian society and medical science facing is to develop healthy aging process and prevention of pathological aging. As we know, healthy aging process depends upon several factors such as heritage, biological and physiological internal factors, living condition, climate, geography, socio-economy, nutrition, drinking water, lifestyle etc,. Thus, the development of healthy aging and its influential factors is an immediate issue of Mongolian medicine and society.A cross-sectional regression analysis has been used to measure socioeconomic and physiological factors for longevity. Total of 1897 participants aged less than 80 are randomly collected from Ulaanbaatar city and Mongolian 4 regions.Total of 1897 participants, less than 80 years old are involved in this study. People in an urban area are higher than those in countryside. About housing condition, 63.5% of total participants are in apartment at UB and 37.8% is in House and 44.3% in Mongolian Ger. Estimating participant’s income, 25% of relatively healthy population is below than the minimum of subsistence. However 50% of elderly people aged between 75-80 is below than minimum of subsistence. Comparing income level by age and gender income is decreased while age is increased, males are relatively higher than females. Middle income people are by 20.9%, high income people are by 57.7% less the risky than low income people. Unhealthy status is increased by 1.0% while a year of smoking, LDL by 96.5%, HDL by 94.7%, Triglycerid by 71.2%, CAVI by 91% increase risks respectively.Below indicators are more influential for the healthy aging of Mongolian elderly people as follows, education level (ρ-0.001), household income (OR=0.423, ρ<0.0001), living conditions (OR=0.326, ρ<0.05), LDL (OR=0.035, ρ<0.0001), HDL (OR=0.053, ρ<0.0001), glucose (OR=0.014, ρ<0.0001), CAVI (OR=0.090, ρ<0.0001). Higher density of healthy aged populations is found in the central region of Mongolia where altitude is 1000-1500 meters above than sea level (MASL) and temperature is between 0-6 Celsius.
6.The effect of musk on cerebral ischemia-reperfusion in rats
Radnaa G ; Oyuntsetseg N ; Enkhsaikhan L ; Bat-Erdene J
Mongolian Medical Sciences 2020;191(1):57-62
Introduction :
In recent years, there has been a significant increase of cerebrovascular disease in Mongolia, which
is the second leading cause of mortality. There are dozens of Mongolian traditional medicine which is
good efficiency for cerebral ischemia that contains musk.
Aim:
Therefore, we aimed to investigate the effect of musk under the cerebral ischemia/reperfusion in rats.
Materials and Methods:
Cerebral middle cerebral artery occlusion was established in male rat (90-minute occlusion followed by
24-hour reperfusion). Rats were divided into following groups: control group, ischemia group (cerebral
ischemia and reperfusion), nimodipine administrated group (cerebral ischemia and reperfusion +
treated with nimodipine), musk administrated group (cerebral ischemia and reperfusion + musk 50
mg/kg and 100 mg/kg). The brain tissue levels of IL-1β, TNF-α, IL-6, IL-10 cytokines were measured
using enzyme linked immunosorbent assay (ELISA) every 1, 3, 7th days.
Results:
Levels of cytokines (IL-1β, TNF-α and IL-6) were significantly lower in musk treated group compared
to brain ischemia group (p<0.05). In contrast, treatment with musk was significantly improved
neurological function with stimulation of M2 phenotype microglia cells and increased the anti-inflammatory cytokine level of IL-10 in the ischemic hemisphere of brain in rats
Conclusion
The mechanisms of musk are associated with increasing the brain tissue levels of IL-10, and reducing the levels of proinflammatory cytokines such as IL-1β, TNF-α, IL-6 subsequently
stimulating neurogenesis and reduced ischemic zone. Musk may have neuroprotective effects
against cerebral ischemia with stimulating M2 phenotype microglia cells in the brain. Regarding the
ELISA, the effects of musk may be due to anti-inflammatory properties through inhibition of some of
proinflammatory cytokines and stimulation of anti- inflammatory cytokines.
7.Study Of Managchenmo Liver Protective And Bile Secretion Effects On Ccl4- Induced Hepatotoxicity
Zolzaya N ; Alimaa T ; Chimedragchaa ; Ch ; Uranzaya D ; Bat-Erdene J
Journal of Oriental Medicine 2014;6(1):11-16
Managchenmo is a traditional Mongolian medicine functional liquor comprising
twelve crude drugs: Sus scrofa / cinis faecis /, Inula helenium L., Terminalia
chebula Retz., Melia toosendan Sieb, Gardenia jasminoides Ellis, Lagotis integrifolia
(Willd.)Schischk, Gentiana barbata Froel, Moschus moschiferus, Bezoar Bovis,
Calcio sinteris, Carthamus tinctorius L,and Saccharum officinarum. Nowadays the
Mongolian traditional herbs are more preferable than the chemical ones; for this
reason studies on their use history and new technologies are conducted. Thus we
study Managchinmo affects, herb for treatment of liver hot disorders, on trial rats
(Handa.S.S, Sharma.A .1990 ) with hepatotoxicity. The levels of serum alanine
aminotransferase (ALT), aspartate aminotransferase (AST) and
alkalinephosphatase (ALP) were determined through biochemical methods. The bile
duct was cannulated with a tube to collect bile for two hours and bile flow was
calculated by the weight of each specimen. Our results showed that Managchenmo
(150 mg/kg) significantly prevented CCl4-induced changes in bile flow and serum
levels of ALT, AST, and ALP. In conclusion, Managchenmo exerted a protective
effect on CCl4-induced hepatotoxicity in rats.
8.Outcomes of Mandibular Reconstruction Using Free Flap After Head and Neck Cancer Resection and Approaches for Improvement
Unubold E ; Denis S ; Odontungalag Ts ; Yanjinlkham M ; Amarsanaa G ; Tsetsegkhen N ; Gantsetseg G ; Battsengel B ; Gan-Erdene B ; Bat-Erdene M ; Bulganchimeg S ; Ganbaatar Yu ; Odkhuu J ; Enkh-Orchlon B
Mongolian Journal of Health Sciences 2025;87(3):82-89
Background:
Reconstruction of mandibular and maxillary defects resulting
from malignant tumors has remained a complex challenge in recent years. Defects
caused by tumors—as well as trauma, inflammatory diseases, and congenital
anomalies—lead to impaired essential functions such as mastication,
swallowing, and speech. Prior to the 1950s, reconstruction of maxillofacial
hard tissue was not commonly performed. Instead, metal plates were used to
reestablish bony continuity, and surrounding tissues were utilized to close soft
tissue defects, without effectively restoring function.
With modern advances in three-dimensional (3D) virtual planning, it is now possible
to accurately plan free bone flaps for reconstructing jaw defects. During
surgery, manually bending reconstruction plates to fit donor bone precisely is
often not feasible. Preoperative 3D planning allows for precise fabrication of
surgical guides and fixation plates, improving accuracy and significantly reducing
operative time. Additionally, incorporating dental implant planning into
the reconstruction process facilitates restoration of both structural and functional
outcomes.
Aim:
To evaluate the outcomes of mandibular defect reconstruction using
scapular free flaps in Mongolia and explore potential approaches to optimize
the technique.
Materials and Methods:
This was a case study series. Data from reconstructive
surgeries performed at the National Cancer Center of Mongolia, Central
Dental Hospital, and the Mongolia-Japan Hospital were collected. Variables
included patient age and sex, etiology of the mandibular defect, size of the
scapular bone segment, operative time, ischemia time of the free flap, number
of vascular anastomoses performed, and pedicle length.
For 3D planning, CT scans of the patient's head and lower limb (slice thickness
<1 cm) were used to generate 3D models via the 3D Slicer software. Cutting
guides for the mandible and scapula (ASIGA), as well as the reconstruction
models (AMS), were printed using a 3D printer.
Results:
A total of 400 free flap reconstructions were performed during the
study period. Of these, 29 cases involved reconstruction of mandibular defects
using scapular free flaps. The mean age of patients was 40.0 ± 18.3 years,
with 52% (15 patients) being female. The etiologies of the defects included
malignant tumors (13 cases, 45%), benign tumors (6 cases, 21%), and pre-existing
defects (10 cases, 34%).
In one case, tumor resection and mandibular reconstruction were performed
using 3D planning. The total operative time was 9 hours and 30 minutes, and
the ischemia time was 2 hours and 40 minutes.
Conclusion
Between 2012 and 2025, a total of 29 mandibular reconstructions
using scapular free flaps were performed in Mongolia. Traditional reconstruction
methods were associated with prolonged ischemia time. The use of
3D surgical planning has shown potential in significantly reducing ischemia
time and improving surgical outcomes.
9.Quality Assurance of Gastrointestinal Endoscopy Unit - A Single Center Study
Sarantuya Ts ; Amarjargal B ; Tungalag B ; Khishgee D ; Amarmend T ; Delgertsog T ; Amarjargal E ; Sarantuya G ; Gan-Orshikh L ; Enkhjargal B ; Sarantsatsral D ; Burentungalag A ; Nandintsetseg B ; Tserendolgor Ts ; Sattgul Sh ; Javzanpagma E ; Suvdantsetseg B ; Khashchuluun O ; Ouynkhishig N ; Munkhtuya E ; Uranchimeg M ; Oyuntungalag L ; Myadagmaa B ; Bat-Erdene I ; Batgombo N ; Saranbaatar A
Mongolian Journal of Health Sciences 2025;86(2):165-170
Background:
Accreditation of healthcare institutions serves as a fundamental mechanism for ensuring patient safety
and validating the quality of medical services provided to the population. At Intermed Hospital, a quality measurement
system for healthcare services has been established since 2015, encompassing 126 quality indicators at both institutional
and departmental levels. This system facilitates continuous quality improvement efforts. In this context, quality indicators
specific to the endoscopy department play a pivotal role in objectively assessing the quality of endoscopic services.
Aim:
To assess the quality indicators in gastrointestinal endoscopy unit.
Materials and Methods:
A retrospective single-center study was conducted by collecting data from the Intermed hospital’s
electronic information systems which included HIS and PACS and Quality and Safety Department’s Database and the results
were processed using the SPSS software. Ethical approval was granted by the Intermed hospital’s Scientific research
committee. The quality of endoscopic services in the Intermed hospital was assessed based on: a) the average values of
four quality indicators measured monthly; b) sample survey data from five categories of quality indicators.
Results :
Between 2016 and 2024, the quality indicators of the endoscopy unit measured as the level of early warning
score evaluations for patients was 95.97%±3.33, the level of cases where peripheral blood oxygen saturation decreased
during sedation was 1.54%±3.78, the level of cases where patients experienced paradoxiical response during sedation was
5.82%±1.75, surveillance culturing level for validation of endoscopy reprocessing was 11.6%. The endoscopic documentation
quality by peer review showed 95.7-100%, the colonoscopy quality indicators were followings as adenoma
detection rate: 24.5% Cecal intubation rate: 99.1%, 95.2%, Colonoscope withdrawal average time: 13.28±10.62 minutes,
Bowel preparation quality (Boston Scale): 89.3% 95.7%), patient discharge from the recovery room, Average discharge
time post-procedure: With propofol alone: 30.92 minutes; With propofol and fentanyl combined: 31.52 minutes, The intermediate
risk was 0.28% by the TROOPS evaluation during procedural sedation.
Conclusion
The quality benchmark levels for these endoscopic units, as determined by a single-center study, can be
effectively implemented by benchmark endoscopy centers to enhance their quality and safety operations.