1.Widespread intracranial calcifications in a patient with hypoparathyroidism.
Jeong Young SEO ; Ju Hyun SEO ; Younghee CHOE ; Hannah SEOK ; Tae Seo SOHN
The Korean Journal of Internal Medicine 2016;31(2):409-410
No abstract available.
Basal Ganglia Diseases/diagnostic imaging/drug therapy/*etiology
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Calcinosis/diagnostic imaging/drug therapy/*etiology
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Calcium/therapeutic use
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Dietary Supplements
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Female
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Humans
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Hypoparathyroidism/*complications/diagnosis/drug therapy
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Middle Aged
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Tomography, X-Ray Computed
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Treatment Outcome
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Vitamin D/therapeutic use
2.Delirium and Extrapyramidal Symptoms Due to a Lithium-Olanzapine Combination Therapy: A Case Report.
Cengiz TUGLU ; Esin ERDOGAN ; Ercan ABAY
Journal of Korean Medical Science 2005;20(4):691-694
We report an elderly patient who developed severe delirium and extrapyramidal signs after initiation of lithium-olanzapine combination. On hospital admission, serum levels of lithium were found to be 3.0 mM/L which were far above toxic level. Immediate discontinuation of both drugs resulted in complete resolution of most of the symptoms except for perioral dyskinesia which persisted for three more months. We critically discussed the differential diagnosis of lithium intoxication and assessed confounding factors which induce delirium and extrapyramidal signs related with combination therapy of lithium and olanzapine.
Antipsychotic Agents/adverse effects/therapeutic use
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Basal Ganglia Diseases/*chemically induced
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Benzodiazepines/adverse effects/therapeutic use
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Bipolar Disorder/drug therapy
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Delirium/*chemically induced
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Drug Therapy, Combination
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Female
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Humans
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Lithium/*adverse effects/therapeutic use
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Middle Aged
3.Sulpiride in Meige's Syndrome: Possible Role of Glutamate.
Sang Am LEE ; Jin Soo KIM ; Jae Hoon AHN ; Kyoung Gyu CHOI
Yonsei Medical Journal 1988;29(1):62-65
Sulpiride, a selective antagonist for adenylate cyclase-independent dopamine receptors, was administrated to 25 patients with blepharospasm and oromandibular dystonia(Meige's syndrome). Of the 25, 7 patients (28%) exhibited marked and lasting improvement with sulpiride and 12 patients (48%) showed mild or transient improvement. This favorable therapeutic response to sulpiride suggests that striatal glutamate underactivity may play a role in the pathophysiology of Meige's syndrome as a primary or secondary defect.
Adult
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Aged
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Basal Ganglia Diseases/*drug therapy
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Corpus Striatum/metabolism
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Dopamine/metabolism
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Female
;
Glutamates/metabolism
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Glutamic Acid
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Human
;
Male
;
Meige Syndrome/*drug therapy/metabolism
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Middle Age
;
Sulpiride/*therapeutic use