Purpose: To compare different commercial viscoelastics retained in the anterior chamber in terms of their tendency to cause intraocular pressure (IOP) rise Methods: Twenty-one rabbit eyes (3 per group) were injected with 0.1 mL of viscoelastic materials (VEM). Seven different brands of VEM were tested. IOP was measured for 6 days after injection Results: All eyes exhibited increase from baseline IOP. Peak IOP rise occurred at a median with 4 hours from injection. IOPs returned to normal in all eyes by Day 6. No significant differences in IOP patterns were detected in this small series Conclusion: This study suggests that all of the VEM tested have potential to cause IOP rise and that spontaneous return to normal levels was achieved for all groups after six days. (Author)
Animal ; INTRAOCULAR PRESSURE ; INTRAOCULAR PRESSURE/DRUG EFFECTS