Objective To understand the situation of rebuilding sanitary latrine in the rural areas in Qingdao and to evaluate the effect of sanitary latrine improvement, explore the new measure of sanitary latrine improvement in the rural areas. Methods In 2005, the typical method of investigation was used to choose 365 farmers from 8 rebuilding sanitary latrine villages among three counties in Qingdao, and to conduct on-site survey and health questionnaires on the construction of household latrines and excreta treatment, sanitation and related knowledge. Hygienic evaluation was made in accordance with hygienic standard for rural household latrine. Results 100% of the houses had the household latrines, 80.0% were the sanitary latrines, dejecta treatment rate was 78.36%. Conclusion All evaluation indexes reach the high level, the effect of household latrine improvement in the investigated rural areas is satisfactory.

Objective To know the lavatory improvement in the rural areas in Shandong Province in 2005 and to present the data for the decision of the lavatory improvement in countryside in the future. Methods In 2005, 164 villages in 45 counties were chosen and questionaire was used to conduct the investigation. Results 15 338 different type lavatories were constructed, of which the indoor toilets occupied 71.70%, the outdoor toilets occupied 28.30%. About 11.19 million yuan RMB was spent on the program, the average cost of each lavatory was 729.60 yuan RMB. Conclusion The program of lavatory improvement in the rural areas has been finished in Shandong Province in 2005, the data are satisfactory.

Objective To explore the effects of Shaoyao Gancao granule on hair growth,behavior,and the hypothalamic pituitary adrenal(HPA)axis in mice with alopecia areata(AA).Methods Forty-two C3H/HeJ mice were randomly divided into control,model,Shaoyao Gancao granule high-,middle-,low-dose,corticotropin-releasing hormone receptor 1(CRHR1)antagonist,and compound glycyrrhizin tablet(CGT)groups.Photography,dermoscopy,weight analysis,and behavioral measurement were performed.Corticotropin-releasing hormone(CRH),adrenocorticotropic hormone(ACTH),cortisol,glucocorticoid receptor(GR),and brain-derived neurotrophic factor(BDNF)were also assessed.Results Compared with the model group,high-dose Shaoyao Gancao granules improve hair regeneration and weight gain(P＜0.05),increased the percentage of total exercise distance and central area exercise distance in an open field test(P＜0.05),reduced the immobility time in the forced swimming and tail suspension experiments(P＜0.05),reduced peripheral blood levels of CRH,ACTH,and cortisol(P＜0.05),and increased expression of GR and BDNF in the hippocampus(P＜0.05).Conclusions Shaoyao Gancao granule promotes hair growth and improves behavioral performance in mice with AA.These effects may be related to downregulating CRH,ACTH,and cortisol expression,upregulating GR and BDNF expression,and inhibiting excessive activation of the HPA axis.

Chlorfenapyr is a moderately dangerous insecticide widely used in agriculture. The mortality of acute poisoning patients is high, and there is no effective treatment. This paper retrospectively analyzes the clinical data of two cases of compound chlorfenapyr poisoning. The main symptoms of the patients were high fever, sweating, gradual coma, increased creatine kinase and myoglobin, with delayed poisoning symptoms. Despite comprehensive treatment, both patients died eventually. It indicated that chlorfenapyr was highly toxic and had a high mortality. In addition to routine symptomatic treatment for patients with acute poisoning, blood purification treatment should be actively carried out in the early stage.

Chlorfenapyr is a moderately dangerous insecticide widely used in agriculture. The mortality of acute poisoning patients is high, and there is no effective treatment. This paper retrospectively analyzes the clinical data of two cases of compound chlorfenapyr poisoning. The main symptoms of the patients were high fever, sweating, gradual coma, increased creatine kinase and myoglobin, with delayed poisoning symptoms. Despite comprehensive treatment, both patients died eventually. It indicated that chlorfenapyr was highly toxic and had a high mortality. In addition to routine symptomatic treatment for patients with acute poisoning, blood purification treatment should be actively carried out in the early stage.