Objective To compare the diagnostic efficacy and complications of transperineal prostate biopsy for<10 cores biopsy vs≥10 cores biopsy. Methods Nine hundred transrectal ul-trasound-guided transperineal prostate biopsies were performed. Patients were divided into 2 groups, <10 cores group and ≥10 cores group. Patient numbers of the 2 groups were 759 and 141, respec-tively. Cancer positive rate and complications were compared between the 2 groups retrospectively. Results Cancer positive rates were 41.6%(316/759) and 51.8%(73/141) in 2 groups (P<0.05). In patients of PSA≤10.0 ng/ml, cancer positive rates were 6.8% (16/235) and 17.8% (8/45) in 2 groups (P<0.05). Gross hematuria was the most common complication associated with biopsy. There was no statistical difference between the 2 groups in post-biopsy gross hematuria rate. Conclu-sions The diagnostic efficacy is higher in≥10 cores prostate biopsy than that in <10 cores prostate biopsy, There is no difference in biopsy related complications regarding biopsy core numbers.

Coronavirus disease 2019 (COVID-19), characterized by high infectivity and invisibility, has spread quickly throughout the world and brought great challenges to hospital security work. Regarding the medical service reality of large general hospitals, the Security Department actively responded to the epidemic prevention and control work. They classified the risk areas in the hospital and formulated corresponding security strategies. Current paper summarize the improvement of the existing security management and control system, the management level of major public health emergencies and the emergency management. Then the control measures for scientific deployment of personnel and proper planning of the diagnosis and treatment process of risk patients during the epidemic are discussed. This study aimed to provide helpful reference for ensuring the stability of medical reception order in large general hospitals under COVID-19 epidemic.