1.A study of osteoporosis in patients with type-2 diabetes
Baoling HAN ; Yang ZHANG ; Fengping HANG
Chinese Journal of Practical Internal Medicine 2001;21(4):214-215
Objective To investigate osteoporosis and its main associated factors in patients with type 2 diabetes (DM). Methods Bone mineral density(BMD)of lumbar vertebrae 2~4 and proximal femur in 40 type 2 diabetic patients were measured with dual energy X-ray absorptiometry and compared with control group(30~35 years old). Serum Ca, P, ALP and connective peptide in type 2 diabetes mellitus patients were measured. Results The area under the connective peptide releasing curre in osteoporosis group was lower than that of non-osteoporosis in type 2 diabetes. Conclu.sion BMD is correlated with the pancreatic islet function. The patients with pancreatic islet failure develop osteoporosis easily.
2.Urinary System Infections in Type 2 Diabetes Mellitus Patients:Clinical Characteristics and Prevention
Baoling HAN ; Jing HAN ; Fang ZHANG ; Jing CAO
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To investigate the clinical characteristics and prevention of urinary system infections in type 2 diabetic patients.METHODS An analysis of pathogens and clinical characteristics of 120 hospitalized type 2 diabetic patients complicating urinary system infections was performed.RESULTS In type 2 diabetic patients complicating urinary system infections,the most common pathogen was Escherichia coli,the next were Staphylococcus epidermidis,Klebsiella pneumoniae,etc.There were no significant difference of pathogens between symptom group and non-symptom group.But they were obviously more among senile patients aged over 60 in non-symptom group than that in symptom group(P
3.Clinical observation of dynamic blood sugar monitoring combined with insulin pump in the treatment of newly diagnosed type 2 diabetes mellitus in the elderly
Lijun DUAN ; Yang ZHANG ; Baoling HAN ; Xia JIANG
Chinese Journal of Geriatrics 2014;33(8):881-883
Objective To evaluate islet cells functional recovery and clinical effects of dynamic blood sugar monitoring combined with insulin pump in newly diagnosed type 2 diabetes mellitus in the elderly.Methods 300 cases with newly diagnosed type 2 diabetes mellitus were randomly divided into treatment group (n=150) and control group (n=150) accompanying with three months follow-up.Body mass indexes (BMI),levels of hemoglobin A1c (HbA1c),fasting plasma glucose (FPG),2-h postprandial blood glucose,fasting insulin,2-h postprandial insulin,fasting C-peptide,2-h postprandial C peptide,and the percentage of patients who took oral hypoglycemic drugs alone without insulin could well control the blood glucose were compared between the two groups before versus after treatment.Results The levels of BMI,HbA1c,FPG,2-h postprandial blood glucose,fasting insulin,2-h postprandial insulin,fasting C peptide,2-h postprandial C peptide in the two groups were significantly decreased after treatment as compared with the pretreatment (P < 0.05).The improvement of blood sugar spectrum was better in treatment group than in control group(P<0.05) and the percentage of patients who took oral hypoglycemic drugs alone without insulin could well control the blood glucose was significantly higher in treatment group than in control group(21% vs.3%,x2 =22.475,P<0.05).Conclusions The clinical effects of dynamic blood sugar monitoring combined with insulin pump on newly diagnosed type 2 diabetes mellitus in the elderly is definite and can improve the recovery of islet cells function.It is worthy of clinical promotion.