In order to enable centralized oxygen supply a healthy development,this paper introduces five kinds of mistakes in the application of centralized oxygen supply technique.

This article introduces the performance, merits and shortcomings of several air conditioning systems employed in HBO chamber. The improvement methods of this system are also recommended.

Oxygen is used broadly in different levels of hospital in the whole country. The method of oxygen supply system changes from bottled, liquid to machine-made. The theories of these methods are introduced, and the danger of conflagration among these methods are especially analyzed and compared. To ensure the fire control, precautions are established so as to serve hospital better.

When prostate cancer （PCa） progresses to the metastatic castration-resistant stage， significant challenges arise in clinical treatment. Microtubulin inhibitors have become first-line drugs for the treatment of metastatic castration-resistant PCa due to their unique mechanism of action. Among them， taxanes （e.g. docetaxel and cabazitaxel） remain standard care with proven survival benefits， while other microtubule inhibitors （e.g. vincristine， colchicine） show limited clinical utility due to toxicity. Currently， the clinical approach primarily employs docetaxel-based triple therapy and combined with immune checkpoint inhibitors to improve the prognosis of PCa patients， reverse the immunosuppressive state of the tumor microenvironment， and enhance therapeutic efficacy. Despite the remarkable clinical efficacy of microtubule inhibitors in the treatment of PCa， the emergence of drug resistance has limited their long-term application. To address this issue， researchers have explored new solutions， including the development of novel microtubule inhibitors in combination with ATP-binding cassette subfamily B member 1 inhibitors， the concurrent use of fatty acid synthase inhibitors with microtubule inhibitors， and the development of degraders based on proteolysis-targeting chimeras technology. Future research should focus on target discovery， drug formulation optimization， and personalized approaches to overcome current therapeutic limitations.