Objective To assess the value of enhanced multislice spiral CT (MSCT) scan using fat-dense enema for the staging of colorectal carcinoma.Methods 33 cases with colorectal carcinoma confirmed by colonoscopy were examined by enhanced MSCT scan ,from the dome of the diaphragm to symphysis pubica,after bowel cleaning,administration of smooth muscle relaxant, and rectal fat-dense contrast agent insuffation .Carcinomas were staged with TNM by axial,multiplannar reconstruction(MPR) and CT virtual endoscopy (CTVE) images. The staging results on CT were compared with that of postoperative pathological examination in all cases.Results All the 33 colorectal carcinoma were demonstrated clearly by MSCT ,the total accurate rate in staging with the TNM classification was 78.78%.The sensitivity and positive accurate values for T staging were 100%and 87.88%(29/33),respectively. The sensitivity and positive accurate values for in detecting lymph node involvement were 86.36%(19/22)and 68.18%(15/22), respectively. Five cases in M stage were all diagnosed correctly. Conclusion Using fat-dense contrast medium and enhanced multislice spiral CT is of very important value in staging of colorectal carcinoma.

Objective: The topographical mapping technique of brain evoked potential was used to observe the changes of the functional activities in the cortical somatosensory area I (SⅠ) during imitating the sensation conduction along the Meridian (SCM). The formation mechanism of sensation conduction was discussed here. Method: 26 healthy adult volunteers were chosen as observe object. Cerebral electric signal processing system was used to record topographical mapping of evoked potential in SⅠ outside the skull. Soft paintbrush was used to slightly brush the Gall Bladder Meridian (GBM) to imitate the sensation conduction. Result: Evoking responses appeared in both foot and face representation areas in SⅠ of 11 healthy volunteers without conduction sensation during imitation of sensation conduction along the GBM (SCGBM), which coincided with the distribution of responses evoked in SI during sensation conduction along Meridian . 15 healthy volunteers were offered imitation of SCGBM as well as brushing through the upper arm additionally, while, the results showed that the evoking responses appeared in the foot, the upper arm and the face representation area of SⅠ. So, it formed a high potential response belt that was similar to the course occurred during the imitation of SCM. Conclusion: The external stimulation along the meridian course can change the distribution of evoking responses in SⅠduring stimulating point. The results provide experimental evidence for the supposition that “activation in sequence in periphery” is the decisive factor for the formation of SCM.

Objective To summarize 5 otospongiosis cases with profound sensory hearing loss who received cochlear implante(CI) in routine way.To analyze their characteristics in audiology and temporal CT,and the effects after CI.Methods 5 cases of profound sensorineural hearing loss with otospongiosis received pure tone test,otoacoustic emission,auditory brainstem evoked potential and temporal CT before operation.One of the patients received binaural CIs.Mapping was done one month after operation.Follow-up tests were provided 6 months after operation to assess the effects.Results 5 cases showed clinical characteristics of gradual binaural hearing reduction,PTA greater than 90 dB HL,mixed or sensorineural deafness,normal tympanic membranes,reduced peaks in acoustic impedance,and typical CT findings.5 patients(6 ears) were implanted in routine manner.It was difficult to open the cochlea scala tympani.The scala tympani was filled with loose bony tissues.It was about 7～9 mm between the round window and the normal scala tympani.All patients showed the standard wave from in nerves reaction remote monitoring.The patients were followed up from 8 months to 3.1years.The average PTA was 20～37dB HL.The speech discrimination score was 95%～99% for open Chinese audiometry.Conclusion CI was an effective way to help patients with profound sensory hearing loss and otospongiosis.

BACKGROUND: Without any external stimuli in natural environment, it is applicable to observe the infrared radiant track over human body surface that is in conformity basically with the running courses of ancient fourteen meridians.OBJECTIVE: To probe into the influence of electroacupuncture on infrared radiant track along meridian courses over human body surface.DESIGN: Self-controlled opening experiment.SETTING: Department of Meridian Research of Academy of Traditional Chinese Medicine in Fujian Province.PARTICIPANTS: The experiment was performed in Key Laboratory of Meridian Research of Fujian Province from January 2000 to December 2002. Totally 53 students from Department of Acupuncture and Massage of Fujian College of Chinese Medicine were observation, of which, 38 students were males, 15 students were females, aged varied from 19 to 23years.METHODS: The receptors exposed completely the body areas required and sat quietly for 20 to 30 minutes to adapt to the environmental temperature. In natural state, 6T67 infrared thermo tracer produced by Japanese San-Ei Company was used to observe 1 to 2 infrared radiant tracks in advance as the control before acupuncture (scanned once per second). Afterwards, acupuncture was done on Guangming (GB 37), Neiguan (PC 6) and Dazhui (GV 14). The stimulation was given by a pair of stainless filiform needles, 6.6 cm long. The frequency of effectric pulse was 2 Hz, and 0.2 ms in duration. The video record was taken once every 5 to 10 minutes during stimulation. After acupuncture, 1 to 2 infrared radiant tracks were scanned.MAIN OUTCOME MEASURES: Tracks of isothermal display and whole thermal display on infrared thermography.infrared radiant track along meridian courses over the human body surface high basic temperature, acupuncture decreased skin temperature on infrared radiant track along meridian courses over the human body surface in a part of subjects. The skin temperature of a part of subjects was decreased acupuncture increased skin temperature on infrared radiant track along though it did not great affect the skin temperature on infrared radiant track along meridian courses over the human body surface in a part of subjects,acupuncture induced infrared radiant track to be more continuous and human body surface, acupuncture stimulates the infrared radiant track displayed along the meridians over human body surface, too.CONCLUSION: Infrared radiant track along meridian courses over the human body surface is a kind of normal life phenomenon existed commonly among peoples. Acupuncture not only induces the infrared radiant track of the related meridian, but also alters the skin temperature of the displayed infrared radiant track along meridian courses and makes it become more continuous and regular. Changes in tissue temperature are relevant necessarily with altered energetic metabolism. It is suggested that infrared radiant track along meridian courses is closely contributed to functional regulation of the human body.

Objective: To investigate the distribution features of somatosensory cortical evoked potential map with augmented blocking of the sensation transmission along meridians.Method: The EEG-4400 electro-encephalogram (EEG) and ND-1 brain electrical activity mapping were adopted on 11 volunteers with remarkable sensation transmission along meridians, showing that the sensation can transmit to head and face after stimulating the points below the knee joints. Also, special observation was made on accurate location of somatosensory cortical evoked potential map in 10 people without sensation transmission.Result: Observation on 11 volunteers with remarkable transmission along the Three Foot-yang Meridians showed that they presented with concurrent high potential reactions in somatosensory cortical lower limbs and face without blocking the augmented sensation transmission along the meridians; however, when mechanical pressure was exerted to block the sensation transmission,only one reaction in the lower limbs occurred in the somatosensory cortical evoked map and the other one in the face disappeared. Conclusion: Peripheral tissue evoking is the decisive factor for transmission along the meridians.

OBJECTIVE Investigating the distribution and drug-resistance of pathogenic bacteria in urinary tract infecion for children in Wuhan region to provide the evidence of diagnoses and treatment for clinician.METHODS The positive results of urine culture of 405 children with urinary tract infections from Jul 2002 to Dec 2005 were analyzed.All of the isolates were tested by Kirby-Bauer susceptibility method.RESULTS Among 405 pathogens,the majority was Escherichia coli which occupied 36.7%;then Enterococcus accounted for 29.4%.Totally 405 pathogens all showed the higher drug resistance,while antibacterial antivities of imipenem,amikacin and furantoin to E.coli and Klebsiella pneumoniae and of glycopeptides,high concentration of streptomycin and furantoin to Enterococcus were preserved well.CONCLUSIONS The effective measurements and reasonable use of antibiotics should be taken to hold back the occurrence and prevalence of urinary tract infecion for children.

OBJECTIVE To investigate dynamically antibiotic resistance changing of Escherichia coli in Hubei province and provide the reference for clinical rational application of antibiotics.METHODS The WHONET4-5 software was used to analyze the antibiotic resistant rates of 2901 strains of E.coli isolated from all kinds of clinical specimen of children from 2003 to 2006 in the third grade hospitals of Hubei province.RESULTS Drug-resistance rate of E.coli in children group was lower than that in adult group.Except for 100.0% susceptibility to carbopenems such as imipenem and Meropenem,in the four years,drug-resistance of the other antibiotics showed ascending tendency.Ampicillin showed the highest drug-resistance rate(84%-90%).The lower(3%-25%) were amikacin,cefoxitin,ceftazidime,cefepime.CONCLUSIONS Antibiotic resistance of E.coli in children in Hubei province showed the ascending tendency.We should take effective measurement to control the spread and prevalence of the drug-resistant bacteria.

OBJECTIVE To approach biosafety risks in laboratory department of children′s hospital to formulate the managemen strategy.METHODS The existing biosafety risk in laboratory department of children′s hospital was investigated and analyzed.RESULTS A series of problems such as personnel′s biosafety consciousness,work environment,protection equipment,a medical orderly′s training,etc were existing.CONCLUSIONS Biosafety regulations should be executed strictly in children′s hospital,and biosafety management should be highly paid attention to and consummated.

OBJECTIVE To study the distribution of drug-resistant gene of meticillin-resistant coagulase negative Staphylococcus(MRCNS) in children septicemia.METHODS The total MRCNS isolates were 40,and whether in there harbored genes mec,erm and qac was studied.RESULTS Among 40 CNS strains,in there harbored genes mec,erm,and qac were 38(95.0%),30(75.0%) and 18(45.0%),respectively.CONCLUSIONS MRCNS in children septicemia where harbor drug resistance genes is very serious,so we should pay great heed to its effective control.

Non-contact measurement is an effective method of long time measurement of human electrocardiograph (ECG) signal. Because the relative position between measuring electrode and human body is not fixed, this method could result in constant changes of ECG signal collection. It often appears ECG signal distorting and weakened in filtering. This paper, using the principal component analysis (PCA) basic theory, proposes a fast adaptive PCA denoising algorithm which can automatically adjust the parameters according to the changes of ECG signal. The experiment proved that PCA denoising could be barely impacted by signal changes and can disposably remove interference signal on the premise of keeping the main features of ECG signal and can prevent ECG signal from being weakened in filtering at the same time.
Algorithms ; Artifacts ; Electrocardiography ; methods ; Humans ; Principal Component Analysis ; Signal Processing, Computer-Assisted ; instrumentation