1.Effect of omega-3 fish oil fat emulsion on the peripheral neuropathy caused by bortezomib.
Xing-xing LONG ; Ya GAO ; Bao-hong PING
Chinese Journal of Hematology 2011;32(9):633-634
Boronic Acids
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adverse effects
;
Bortezomib
;
Fatty Acids, Omega-3
;
administration & dosage
;
therapeutic use
;
Fish Oils
;
administration & dosage
;
therapeutic use
;
Humans
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Male
;
Middle Aged
;
Peripheral Nervous System Diseases
;
chemically induced
;
drug therapy
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Pyrazines
;
adverse effects
2.Treatment of Sepsis-associated Encephalopathy by Xingnaojing Injection: a Clinical Observation.
Su LV ; Jia LI ; Bao-ping CAO ; Ji-hong ZHU
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(7):792-795
OBJECTIVETo observe the efficacy of Xingnaojing Injection (XI) in treatment of sepsis-associated encephalopathy (SAE).
METHODSTotally 65 SAE patients were retrospectively analyzed at EICU from September 2010 to September 2013. They were assigned to the control group (32 cases) and the treatment group (33 cases) according to whether they received XI. Patients in the control group received anti-infection and symptomatic support, while those in the treatment group were intravenously injected with XI at 20 mL per day for additional 7-10 days. The fever clearance time, Glasgow coma scale (GCS), C-reactive protein (CRP), neuron-specific enolase (NSE), and improvement of electroen-cephalogram (EEG) were observed in the two groups.
RESULTSCompared with the control group, the fever clearance time was shortened, CRP levels decreased, GCS score and efficacy of EEG was alleviated in the treatment group after treatment with statistical difference (P < 0.05). No adverse reaction occurred during medication.
CONCLUSIONX1 was safe and effective in treatment of SAE.
C-Reactive Protein ; metabolism ; Drugs, Chinese Herbal ; administration & dosage ; therapeutic use ; Humans ; Injections ; Phosphopyruvate Hydratase ; metabolism ; Sepsis-Associated Encephalopathy ; drug therapy ; Treatment Outcome
5.The clinical application of superficial circumflex iliac artery flaps.
Guo-Hong BAO ; Chao-Shuai HUANG ; Xiao-Ping ZHU
Chinese Journal of Plastic Surgery 2013;29(6):440-443
OBJECTIVETo investigate the clinical application of pedicled superficial circumflex iliac artery (SCIA) flaps in Burns and Plastic Surgery.
METHODS19 cases with skin and soft tissue defects were repaired with the Superficial circumflex iliac artery flaps. The defects located in the hand and forearm, the lower abdomen and perineal area, the radicle area of thigh, etc. Before the SCIA flaps were transfered to the recipient areas, 15 cases with different kinds of wounds were debrided thoroughly, 3 cases with scar were removed directly. The size of the flaps ranged from 3.0 cm x 4.5 cm to 26.0 cm x 22.0 cm, and the pedical was 5 cm to 7 cm in length.
RESULTSThe flaps in the 18 cases survived completely. Skin necrosis in the distal end of the flap appeared in 1 case, and the wound healed after the second repair. The follow-up period rang from 3 to 18 months. The apperance and function of the hand or foot was satisfactory.
CONCLUSIONSBecause the pedicled SCIA flaps can be obtain conveniently and contain sufficient blood-supply, so the flap is easy to survive and the flap can be designed in a large size. We believe it is an ideal method to use this flap to repair skin and soft tissue defects located in hands, forearms, the lower abdomen and perineal areas, the radicle area of thigh and so on.
Burns ; surgery ; Forearm ; Graft Survival ; Hand ; Humans ; Iliac Artery ; Necrosis ; Reconstructive Surgical Procedures ; Soft Tissue Injuries ; surgery ; Surgical Flaps ; blood supply ; pathology ; transplantation ; Thigh ; Wound Healing
6.Correlation between-173 G/C Gene Polymorphism of Macrophage Migration Inhibitory Factor and Henoch-Schonlein Purpura Nephritis
qing, GUO ; bao-jin, HU ; hong-ping, ZHOU ; rui, FU ; hong, LIU
Journal of Applied Clinical Pediatrics 1992;0(05):-
Objective To explore the correlation between-173G/C gene polymorphism of macrophage migration inhibitory factor(MIF) and Henoch-Schonlein purpura(HSP),Henoch-Schonlein purpura nephritis(HSPN) in children in Jiangxi Province.Methods One hundred and thirty-one ethnic Han children with HSP were enrolled,including 80 children with concurrent nephritis(HSPN group) and 51 children without nephritis(HSP without nephritis group).One hundred and five healthy children were used as the healthy control group.Germline DNA was extracted from peripheral blood by Promega blood genomic DNA kit.Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) was used for genotyping the-173G/C polymorphism of MIF.Genotype distribution and allele frequencies were obtained by direct counting.Statistical analysis was performed by using SPSS 11.5 software.Allele and genotype distribution were compared by using the chi-square test.The relative risk of allele was described by odds ratios(OR) and 95% confidence intervals(95%CI).Results Three genotypes(GG,GC,CC) were detected in MIF-173 G/C.GG,GC genotypes were detected in HSP without nephritis and healthy control group.GG,GC and CC genotypes were detected in HSPN group.Mutant genotype(37.5%) and C allele frequency(20.0%) in HSPN group were significantly higher than those in healthy control group(20.0% and 10.0%,respectively)(?2=6.964,7.400,Pa
8.Double-labelling immunofluorescence study by quantum dots for simultaneous detection of two different antigens in paraffin embedded tissues.
Hong-Lei CHEN ; Xiao-Bo ZHU ; Bei-Yun LI ; Bao-Ping YU
Chinese Journal of Pathology 2009;38(6):420-422
Breast Neoplasms
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metabolism
;
pathology
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Cytokines
;
metabolism
;
Female
;
Fluorescent Antibody Technique
;
Humans
;
Microscopy, Fluorescence
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Paraffin Embedding
;
Proliferating Cell Nuclear Antigen
;
metabolism
;
Quantum Dots
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Receptor, ErbB-2
;
metabolism
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Receptors, Estrogen
;
metabolism
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Stomach Neoplasms
;
immunology
;
pathology
10.Exploration of Infectivity of HIV in vitro
Wei-Ping FAN ; Jing-Yun LI ; Zuo-Yi BAO ; Hong-Xia WANG ; Fu-Shuang LV ;
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To define the regularity of survival ability of HIV in natural environment,and prevent(infection) through contacting with positive body fluids during daily life or medical work.METHODS Having been diluted by sterile water or 10% serum RPMI 1640 medium,HIV was exposed to 4℃,room temperature(20-26℃) or 37℃ for different period of time.TCID_(50) of these samples was detected.Non-pathological samples were blind passaged for three generations.RESULTS HIV infective ability persisted more than 35 days both in(water) and medium at 4℃;whereas it persisted 7-14 days in water,14-21 days in medium at room temperature and 37℃.CONCLUSIONS HIV has higher resistance in natural environment.To prevent accidental spreading of HIV,HIV positive liquids and contaminants staffs should be treated carefully.