Humans ; Orthopedics ; methods ; trends ; Traumatology ; methods ; trends

Accidents, Traffic ; statistics & numerical data ; China ; epidemiology ; Humans ; Wounds and Injuries ; epidemiology

Objective To analyze the short term prognosis of very low birth weight (VLBW) infants. Methods The clinical data of VLBW infants who were hospitalized from December 2013 to December 2014 and followed up to 6 months of corrected age were retrospectively analyzed. Results A total of 230 VLBW infants were enrolled. Thirty infants (13.0%) died during hospitalization, 40 infants (17.4%) were given up the treatment, 60 infants (26.1%) were improved at discharge, and 100 infants (43.4%) were cured at discharge. In the 30 cases of death, causes of death were mainly neonatal respiratory distress syndrome (18 cases), pulmonary hemorrhage (5 cases), and sepsis (3 cases). In the 200 survived infants at discharge, at 6 months of corrected age of follow-up, 13 infants (6.5%) were lost to follow-up, and 54 infants (27.0%) died, among whom 40 infants died because of giving up therapeutic intervention due to economic factor or discharges without permission. At 1, 3, 6 month of follow-up, the length and weight of VLBW infants were gradually approaching normal, and, however, at 6 months of corrected age, the length and weight of VLBW infants were still obviously below the children’s growth standard. The length of VLBW infants was more deeply below the growth standard than the weight. In 109 infants who had fundus ophthalmoscope, 21 cases had retinopathy of prematurity (ROP) I, and 7 cases had ROP II. In 98 infants who had the hearing screening test, 5 cases failed in one ear and 11 cases failed in both ears. In 95 infants who had the head magnetic resonance imaging (MRI) examination, 10 cases had intracranial hemorrhage and 9 cases had premature brain injury. In 49 infants who completed the neonatal behavioral neurological assessment (NBNA) at corrected age of 42 weeks, the scores were all lower than 35. In 36 infants who were assessed by Gesell developmental scale at the 3 months of corrected age, 11 cases had mild developmental delay and 2 cases had moderate developmental delay. In 24 infants who were assessed at the 6 months corrected age, only 2 cases had mild developmental delay. VLBW infants had a rapid progress in social contact, social behavior, and gross motor movement. Conclusions Economic, neonatal respiratory distress syndrome, pulmonary hemorrhage, and sepsis are pivotal factors for the survival and quality of life of VLBW infants. The surviving VLBW infants have catch-up growth and development.

Arthroplasty, Replacement ; Fracture Fixation, Internal ; methods ; Humans ; Shoulder Fractures ; therapy ; Shoulder Joint ; surgery

Purpose:In order to determine the indications for adjuvant treatment in node-negative breast cancer.Methods:We analyzed 233 cases of node-negative breast cancer. Results:The recurrence ratio of node-negative breast cancer was 7.3 percent. The prognosis was connected with age,menstrual history , position, diameter of tumor and pathology. Among invasive lobule cancer, GradeⅢ and lymphocyte-negative cancer, the recurrence ratio was 28 percent in patients with three factors, 16 percent in patient with two factors, 7 percent in patients with one factor.Conclusions:Node-negative breast cancer cases with high recurrence factors need adjuvant treatment.

AIM: To establish an apoptotic model induced by 1-methyl-4-phenylpyridinium ion(MPP~+) in PC12 cell and assess the effect of Semen Cuscuta extracts on protecting PC12 cell from apoptosis induced by MPP~+. METHODS: The cell viability was analyzed by MTT method,the morphological changes were observed by Hoechst 33258 staining assay,and the apoptosis rate was measured by flow cytometry analysis(FCM).(RESULTS:) Treatment of 0.15 mM MPP~+ for 48 h induced apoptosis in PC12 cells;concentration of 50 mg/L Semen Cuscuta extracts could protect cells from apoptosis induced by MPP~+. CONCLUSION: MPP~+-induced apoptosis in PC12 cell is greatly inhibited by Semen Cuscuta extracts.

Acupuncture Therapy ; Adult ; Female ; Humans ; Thyroid Neoplasms ; surgery ; therapy

Aortopulmonary Septal Defect ; therapy ; Catheterization ; Female ; Humans ; Infant

Female ; Humans ; Hyperkeratosis, Epidermolytic ; pathology ; Infant, Newborn

Objective To investigate different fentanyl medication methods on propofol intravenous anesthe-sia painless abortion,to provide a reference for clinical treatment.Methods 1 20 patients undergoing painless abor-tion were selected,according to the random number table they were divided into Ciliao point group,subcutaneous group,intravenous injection group,40 cases in each group.Intravenous injection group used intravenous anesthetic propofol,Ciliao point group used Ciliao hole injection anesthesia,subcutaneous group used fentanyl anesthesia subcu-taneous injection.The anesthesia,analgesia and other clinical indicators of complications were compared among the three groups.Results The anesthesia excellent and good rate of Ciliao point group was 97.50%,which was higher than the subcutaneous group,intravenous injection group,the differences were significant(χ2 =4.1 32,3.894,all P <0.05).MAP,HR,SpO2 among three groups showed no statistical differences (P >0.05).Postoperative 4h,8h,VAS scores of Ciliao point group were (2.32 ±0.56)points,(1 .1 3 ±0.23)points,which were lower than those in the subcutaneous group,intravenous injection group,the differences were significant (t =8.656,8.843,6.587,6.335,all P <0.05).The propofol use times,the amount of Ciliao point group were (1 .1 4 ±0.1 4),(1 1 6.37 ±1 4.35)mg respectively,which were less than those in the subcutaneous group,intravenous injection group,the differences were significant (t =6.645,5.587,6.1 32,5.854,all P <0.05).The incidence rate of adverse reaction of Ciliao point group was 2.50%,which of the subcutaneous group was 20.00%,which of the intravenous group was 25.00%,the differences were statistically significant (χ2 =6.596,7.454,all P <0.05).Conclusion Fentanyl uased at Ciliao point can enhance the clinical effect of anesthesia with less postoperative pain and reduce incidence of adverse reac-tions,it is worthy of clinical application.