1.Empirical study of the impact of patients' trust on health outcomes
Chinese Journal of Hospital Administration 2012;28(5):355-359
Objective To identify the relationship between patients' trust and their health outcomes and verify the mediator role played by patients' behavioral intention in affecting the health outcomes.MethodsThe 24-item patients' trust evaluation scale customized based on QOC improvement was called into play to measure the extent of trust of 727 inpatients at two tertiary hospitals and 20community hospitals in Shanghai.The patients' behavioral intention scale,life quality scale and patients'clinical effect general scale helped reveal the patients' behavior tendency on their health.RestltsIt is found that patients' trust affects their health outcomes.Furthermore,such trust plays partial mediator role on patients' life quality,and a complete mediator role in affecting the clinical effect.Conclusion Improvement of patients' behavior can result in better health outcomes.For doctors,better trust from the patients can affect patients' behavioral intention,encourage doctor-patient communication and therapy plans for better health outcomes in the end.
2.Progress in the studies of prostate cancer related molecules.
Wei SHI ; Li DONG ; Jun-sheng BAO
National Journal of Andrology 2015;21(4):357-362
Prostate cancer is one of the common malignant tumors of the urinary system and mostly found in elderly men. Like most tumors, prostate cancer involves a variety of molecules in its occurrence and progression. More studies on the development of prostate cancer focus on the tumor markers, DNA damage repair related genes, and tumor invasion and metastasis related factors. This article presents an overview on the research progress in these three aspects.
Biomarkers, Tumor
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Biomedical Research
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DNA Repair
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Disease Progression
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Humans
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Male
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Neoplasm Invasiveness
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Prostatic Neoplasms
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genetics
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pathology
3.Vulval intraepithelial neoplasia.
Chinese Journal of Pathology 2009;38(9):577-579
Carcinoma in Situ
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pathology
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virology
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Carcinoma, Squamous Cell
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pathology
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virology
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Diagnosis, Differential
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Female
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Humans
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Paget Disease, Extramammary
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pathology
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virology
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Papillomavirus Infections
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Precancerous Conditions
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pathology
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virology
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Vulvar Neoplasms
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classification
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pathology
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virology
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Warts
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pathology
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virology
4.Clinjcopathological features of obesity-associated focal segmental glomerulosclerosis
Bao DONG ; Wen CHEN ; Hong CHENG
Chinese Journal of Nephrology 1997;0(06):-
Objective To elucidate clinical and pathological features of obesity-associated focalsegmental glomerulosclerosis(FSGS). Methods Clinicopathological data of thirteen obese cases (BMI3≥28kg/m2) with FSGS(OB-FSGS) and thirteen non-obese cases(BMI
5.Glandular neoplasia of cervix.
Chinese Journal of Pathology 2006;35(12):744-746
Carcinoembryonic Antigen
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metabolism
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Carcinoma in Situ
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immunology
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pathology
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virology
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Carcinoma, Ductal, Breast
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immunology
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pathology
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virology
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Cervical Intraepithelial Neoplasia
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immunology
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pathology
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virology
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DNA, Viral
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analysis
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Diagnosis, Differential
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Female
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Human papillomavirus 16
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genetics
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isolation & purification
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Humans
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Ki-67 Antigen
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metabolism
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Uterine Cervical Dysplasia
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immunology
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pathology
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virology
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Uterine Cervical Neoplasms
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immunology
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pathology
;
virology
6.Clinical and pathological features of macroscopic hematuria associated acute kidney injury in IgA nephropathy
Chinese Journal of Practical Internal Medicine 2001;0(03):-
Objective The current study was to investigate the clinical and pathological features of macroscopic hematuria associated acute kideny injury (MH-AKI) in patients with IgA nephropathy (IgAN) and its associated prognostic factors.Methods We performed an analysis on the clinical and pathological features of biopsy-proven IgAN patients diagnosed during 2004 to August of 2007,who had experienced MH associated AKI.The patients enrolled in the study were followed up.The renal lesions were evaluated with Katafuchi pathological scores of IgAN.Results 5 patients with IgAN had experienced at least one episode of MH-AKI,accounting for 1.3% of IgAN diagnosed during the same period and 13.5% of IgAN patients with macroscopic hematuria.High proportion of tubules filled with red blood cell casts and tubular injury were demonstrated in all biopsy specimens.Renal function of 3 patients completely recovered within 14 days.One patient (patient 4) got quick recovery in the first month of the disease but completely recovered 418 days later.The other patients only had an incomplete recovery during the 20-month follow-up.The incompletely recovered one had relatively an older age,longer persistence of MH,more sclerotic glomeruli and a more severe tubule-interstitial damage.Conclusion AKI is commonly seen during episodes of MH in patients with IgAN.Not all patients with MH-AKI showed a complete recovery.Age,duration of MH,proportion of glomerular sclerosis and the severity of tubular necrosis might be the risk factors of an incomplete recovery of renal function.
7.The effect of early exercise intervention on deep venous thrombosis after joint replacement
Fengqin DONG ; Ping LI ; Lili BAO
Chinese Journal of Practical Nursing 2016;32(9):641-643
Objective To evaluate the effect of early exercise intervention on deep venous thrombosis (DVT) after joint replacement.Methods 100 patients with joint replacement were divided into observation group including 50 cases and control group including 50 cases by random number table method.Early exercise intervention was used in observation group and usual nursing was used in control group.The hemodynamic index (femoral vein blood flow peak velocity and average velocity) and DVT incidence were compared between the two groups.Results After the intervention for 3 days,the femoral vein blood flow peak velocity and average velocity of observation group respectively were (43.5±4.1) cm/s and (27.3±3.2) cm/s,those of control group respectively were(36.6±3.7) cm/s and (20.2±2.8) cm/s.The difference between the two groups was statistically significant (t=2.987,2.895,P < 0.05).After the intervention for 7 days,the femoral vein blood flow peak velocity and average velocity of observation group respectively were (56.1±4.7) cm/s and (32.1±3.9) cm/s,those of control group respectively were (41.3±3.9) cm/s and (22.4±4.3) cm/s.The femoral vein blood flow peak velocity and average velocity of observation group significantly higher than control group(t=3.675,2.929,P < 0.05).The DVT incidence of control group and observation group respectively were 40.0%(20/50) and 14.0%(7/50),showed significant differences between the two groups(x2=8.574,P=0.003).Conclusions Using the early exercise intervention on patients with joint replacement can effectively improve the lower limb venous blood flow velocity and prevent DVT.
8.Effect of fast track surgery on functional recovery of knee joint replacement
Ping LI ; Fengqin DONG ; Lili BAO
Chinese Journal of Practical Nursing 2016;32(25):1946-1949
Objective To study the effect of fast tract surgery (FTS) used in patients undergoing total knee arthroplasty (TKA). Methods For the experimental group, 341 inpatients with TKA in the Joint Surgery Department of Shandong Provincial Hospital from June 2014 to June 2015 were treated with FTS nursing measures. For the control group, 355 inpatients with TKA of the same department from January 2013 to May 2014 were treated with conventional nursing measures. The effects of FTS nursing measures, the parameters of patients′ postoperative complications, average hospitalization days and the function recovery of knee joint were evaluated respectively. Results After implementing the FTS nursing measures , the incidence of deep venous thrombosis of lower limbs reduced from 8.45%(30/355) to 2.35%(8/341) (χ2=2.340, P<0.05). The average hospitalization days treated without/with FTS nursing measures were:unilateral knee (14.49±3.62) days (without FTS) vs. (11.95±4.53) days (with FTS), bilateral knees (15.80± 3.01) days (without FTS) vs. (13.19±4.08) days (with FTS)(t=3.166, P<0.05). Two weeks after surgery, the HSS scores in the experimental group was 65.72 ± 5.54, while the HSS scores in the control group was 52.43 ± 7.32 (t=2.452, P < 0.05). Three months after surgery, the HSS scores in the experimental group was 88.72 ± 7.10, while the HSS scores in the control group was 72.14 ± 8.73 (t=2.528, P < 0.05). Conclusions FTS nursing measures could significantly reduce the incidence of deep venous thrombosis of lower limbs, shorten the hospitalization days of inpatients, and promote the functional recovery of knees.
9.The clinical and pathologic features of vascular amyloid deposits of amyloid nephropathy in 6 patients
Guming ZOU ; Bao DONG ; Wenge LI
Chinese Journal of Internal Medicine 2011;50(7):576-579
Objective To analyze clinical and pathologic features of a rare vascular amyloid deposits of amyloid nephropathy ( VADAN) in 6 patients, so as to improve its diagnosis and treatment. Methods All patients received immunopathology, microscopy and electron microscopy examination, and amyloid types were analyzed. Results There were 3 males and 3 females with ages ranging from 52 to 73 years. Two patients suffered from multiple myeloma. Majority patients had slight albuminuria and hematuria. One patient combined with minimal change glomerular disease presented nephrotic syndrome. One patient combined with IgA nephropathy had albuminuria and hematuria. And one patient had myeloma cast nephropathy with acute renal failure. Kidney biopsy proved amyloid deposits along interlobular arterial wall only in all 6 patients. Two cases secondary from multiple myeloma were κ amyloid, and the rests were λ amyloid. Conclusions VADAN is a rare type of amyloid nephropathy. Its clinical manifestation is different from common amyloid nephropathy. Kidney biopsy will benefit its differential diagnosis.