Objective To explore the influence of mild hypothermia therapy on expression of heat shock protein(HSP)60,HSP70,HSP90 in lymphocyte in patients with severe craniacerebral injury.Methods 23 patients with severe craniacerebral injury were randomly divided into the mild hypothermia group (12 cases) and the normothermia group(11 cases).At the base of routine therapy,the mild hypothermia group received mild hypothermia therapy by the temperature control blanket to keep the body temperature among 32～34℃ for 4～6 d.The expression of HSP60,HSP70,HSP90 in lymphocyte were measured by Western Blot at the 1st d,4th d and 8th d after treatment.The infection incidence was observed at 7 d after treatment.And the expression of HSPs in lymphocyte at 32℃ and 37℃ in normal control group were measured respectively.Results Compared with normothermia group,the expression of HSP60 in mild hypothermia group was significantly lower at each time point(all P

Objective To evaluate the efficacy of minimally invasive drairage of hematoma in treatment of hypertensive cerebral hemorrhage. Methods 60 patients with hypertensive cerebral hemorrhage were randomly divided into two groups,including the observation group of minimally invasive hematoma drainage, the control group 30 cases, a small bone window intracranial hematoma,observe and compare the two groups of hypertensive cerebral hemorrhage the neurological function recovery. Results The operative time was significantly shorter than that used in the control group. Postoperative mortality, the difference was significant (P