It is now well-known that the electronic data processing system(EDPS: computer) is very useful for indexing, sorting, verification, and so on. And a few orthopedics in Korea are processing informations with computers for their medical records respeetively. But since there are no established principles on the description of orthopedic diseases, a computer programmer unfamiliar with medical terms is poor in electronic processing for medical records. After processing with an IBM computer for several years, it has come to our attention that we have a need for standardization of the description of orthopedic diseases for EDPS. Based largely on the International Classification of Diseases(ICD-9th), we propose the following: 1. Diseases should be written in English, and whether it be capital letter or small letter does not matter. 2. Description of the disease should be in order of title, region of the body, cause or present status, and side of the body. The sequence may be changed without problem, but only the noun form should be used. It is also recommended that the key words in articles be defined. 3. Abbreviated forms should be avoided. If inevitable, the abbreviation should be used consistently from the first to the 1ast. 4. Connection with other types of medical records such as medical insurance system by registering the code number of the International Classification of Disesaes at the end of the description or on another line.
Abstracting and Indexing as Topic ; Automatic Data Processing ; Classification ; Insurance ; Korea ; Medical Records ; Orthopedics

No abstract available.
Follow-Up Studies* ; Prostheses and Implants*

In this animal study, comedones were induced by topical application of oleic acid onto the rabbit ear canal and the histopathologic and ultrastructural changes in response to topical application of HO and hexane extracts of red ginseng, and saponin were measured. No microscopical difference was observed between treatment groups. Nucle ir remnants were observed in the horny cell layer as well as the thinning of the granular cell layer. Scattered and decreased keratohyaline granules were also noted. Six weeks after initiation of treatment, we observed the thinning of epidermis and veappearance of granular cell layer with normal keratohyaline granules. After treatment, scanning electron microscopy showed a decrease in the size of comedones, and loosened and desquamating horny cells in the comedones. From the above results, it could be concluded that Panax ginseng extracts might have effects on the keratinization process of the skin.
Animals ; Ear Canal ; Epidermis ; Microscopy, Electron, Scanning ; Oleic Acid ; Panax* ; Saponins ; Skin

Nevus lipomatosus cutaneous superficialis is a very rare skin disease which usually is present from birth. This uncommon condition is due to collections of ectopic. fat cells within the upper and mid dermis. There are two clinical varieties. The first is a lesion of zonal distribution, present from birth or childhood, usualIy on the buttocks or the lower back. The second form, a dome or sessile, papule, begins. in adult life and is less restricted in distribution. Cerebriform plaques tend to form from the coalescence of soft, yellowish papules. The authors observed two cases of typical nevus lipomatosus cutaneous superficialis. The first case is a 25-year-old female who has had asymptomatic, soft, skin colored, and huge confluent nodules on the right infragluteal fold and upper thigh for 15 years; and the second case is a 15-year-old male who has had multiple, skin colored and soft papules or nodules in zosteriform distribution affecting the right side of the lower back and coccygeal area and right buttock for 4 years. The authors made the diagnosis of nevus lipomatosus cutaneous superficialis from the characteristic clinical and histopathological findings.
Adipocytes ; Adolescent ; Adult ; Buttocks ; Dermis ; Diagnosis ; Female ; Fluconazole ; Humans ; Male ; Nevus* ; Parturition ; Skin ; Skin Diseases ; Thigh

A giant hydronephrosis caused by ureteropelvic junction stricture in a 16-month-old male infant was presented. After the size and volume of giant hydronephrosis were estimated by retrograde pyelography, nephrectomy was performed. We report this case with review of literatures.
Constriction, Pathologic ; Humans ; Hydronephrosis* ; Infant ; Male ; Nephrectomy ; Urography

Mobility shifts in non-denatured gel electrophoresis of PCR-amplified Rif' region in each of fifteen different mutants of M. tuberculosis were discerned by single strand conformation polymorphism (SSCP) analysis. The findings of mobility differences between rifampin-resistant and susceptible strains showed an excellent agreement with data obtained by traditional susceptibility test. SSCP-PCR seemed to replace the cultivation method of susceptibility test that was known to be time-consuming, labor wasting, and skeptical in quality control. After screening of rpoB gene mutation by SSCP-PCR, detection of specific sequence changes in the region of rpoB gene was attempted through the procedures of PCR-amplification, cloning of PCR-products using pGEM-T vector and DNA thermocycling sequencing. Fifteen different types of mutations were identified among fifty strains of rifampin-resistant strains while five rifampin-susceptible control strains showed no sequence changes of rpoB gene as well as reference strain H37rv. Most mutation appeared to be a point mutation due to substitution or deletion except seven mutants showing somewhat complex mutation. Each of mut#ated loci inclined to clustering within a region of eighteen amino acids involving eight codons. The most common mutation of Ser425 shared among twenty-nine mutants and followed by eleven mutants of His420. Several mutants alleles identified in this study appeared to be dissimilar to those of previous reports.
Alleles ; Amino Acid Substitution* ; Amino Acids ; Clone Cells ; Cloning, Organism ; Codon ; DNA ; Electrophoresis ; Mass Screening ; Mycobacterium tuberculosis* ; Mycobacterium* ; Point Mutation ; Quality Control ; Rifampin* ; Tuberculosis

A clinical observation was made on 38 patients with the suspicion of prostatic cancer in the department of urology, St. Mary's Hospital during the period from January, 1969 to December, 1978. The results are as follows. 1. The most prevalent age was from 60 to 69 (44.7%) 2. Among 38 cases of the transrectal needle biopsy, the adequate tissues for the histologic diagnosis were obtained in 34 cases. 3. Of 34 cases whose tissue were obtained adequately by the needle biopsy, 22 cases were diagnosed the malignancy of prostate. 4. Among 38 cases of the transrectal needle biopsy, the fever were developed in 4 cases and the rectal bleeding in one case.
Biopsy, Needle* ; Diagnosis ; Fever ; Hemorrhage ; Humans ; Needles* ; Prostate ; Prostatic Neoplasms ; Urology

A statistical observation was made on 448 in-patients in the Department of Urology Catholic Medical College, during the period from the January 1, 1976 to December 31, 1977.
Urology

Stiff-person syndrome (SPS) is a rare CNS disease characterized by progressive fluctuating rigidity and superimposed muscle spasms. We report a woman who developed stiff-person syndrome in association with breast cancer. A 55-year-old woman had progressive rigidity and intermittent muscle spasms, which predominantly occurred in her right shoulder muscles. Her symptoms were aggravated by unexpected stimuli or emotional stress, but relieved during sleep. Needle electromyography showed continuous motor unit activities in affected muscles, which were completely abolished by general anesthesia. An Anti-GAD antibody test was negative. She also disclosed a subacute sensory neuronopathy, confirmed by nerve conduction study and sural nerve biopsy. Chest CT scan revealed an enlargement of the right axillary lymph node, which was proved to be a metastatic ductal carcinoma of the right breast. The authors report the first case of paraneoplastic stiff-person syndrome with sensory neuropathy of axonal type, which is associated with breast cancer.
Anesthesia, General ; Axons ; Biopsy ; Breast Neoplasms* ; Breast* ; Carcinoma, Ductal ; Central Nervous System Diseases ; Electromyography ; Female ; Humans ; Lymph Nodes ; Middle Aged ; Muscles ; Needles ; Neural Conduction ; Shoulder ; Spasm ; Stiff-Person Syndrome* ; Stress, Psychological ; Sural Nerve ; Tomography, X-Ray Computed

Progressive multifocal leukoencephalopathy (PML) is a rare disease that occurs mainly in immunocompromised patients. Despite the progressive nature of the disease, the changes on MRI during the disease course - which may help in monitoring the disease process - have seldom been reported. Here we describe a patient with polymerase-chain-reaction-proven PML examined using serial diffusion-weighted imaging (DWI) and apparent-diffusion-coefficient mapping. Magnetic resonance spectroscopy (MRS) revealed that the demyelinating process was more active without significant neuronal loss at the newer and advancing edge of a lesion than in the older central part of the lesion. This case shows that MRI findings such as DWI and MRS may improve the diagnosis and the understanding of the pathophysiology of PML.
Diagnosis ; Diffusion* ; Humans ; Immunocompromised Host ; Leukoencephalopathy, Progressive Multifocal* ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy* ; Neurons ; Protons* ; Rare Diseases