The injury of the epiphysis or epiphyseal plate produces undesirable effects on the normal growth of the bone, such as bone bridge, growth arrest and angular deformity. Authors performed vascularized fibular epiphysis and epiphyseal plate transplantation in 7 years old girl, who received the excision of the exostosis on distal ulna, followed by progressive varus deformity of right forearm and growth arrest of distal ulna. With follow
Congenital Abnormalities ; Epiphyses ; Exostoses ; Female ; Forearm ; Growth Plate ; Humans ; Methods ; Transplantation ; Ulna

No abstract available.
Humans ; Incidence* ; Radiculopathy* ; Shoulder Pain* ; Shoulder*

PURPOSE: evaluate the effectiveness of minimally invasive plate osteosynthesis (MIPO) in unstable fractures of the distal tibia. MATERIALS AND METHODS: From March 2001 to December 2003, 21 cases with unstable fractures of the distal tibia were treated with MIPO technique and followed for at least one year. Eighteen cases were extra-articular and three cases were intra-articular fractures. According to AO classification, six cases were 42-A, four 42-B, one 42-C, seven 43-A, and three 43-C. There was only one case of Gustilo-Anderson type II open fracture. We reviewed the results of fracture healing, axial and rotational deformity, ankle motion, and complications RESULTS: All fractures were healed in an average of 16.1 weeks (range, 11 to 24 weeks). There was only one case of 7-degree posterior angular deformity, but no cases of rotational malalignment. Recovery of ankle motion was satisfactory in all patients within 5-degree loss of motion. Subcutaneous abscess was developed in one case after fracture healing and cured by a drainage with implant removal. CONCLUSION: Although MIPO technique is technically more demanding than the traditional open technique, MIPO technique is an effective method for unstable fractures of the distal tibia because it minimizes incidence of soft-tissue compromise and infection and provides good fracture healing.
Abscess ; Ankle ; Classification ; Congenital Abnormalities ; Drainage ; Fracture Healing ; Fractures, Open ; Humans ; Incidence ; Intra-Articular Fractures ; Tibia*

Sunitinib, a multi-targeted tyrosine kinase inhibitor, is used for the treatment of renal cell carcinoma and gastrointestinal stromal tumors. Many adverse effects associated with sunitinib, including hypertension, proteinuria, and thrombotic microangiopathy, have been reported; however, the other forms of glomerulonephritis are very rare. We report a case of biopsy-confirmed immune complex glomerulonephritis in a patient with a gastrointestinal tumor who received sunitinib treatment. The proteinuria subsided partially after sunitinib was discontinued, but when the drug was reintroduced, it recurred.
Antigen-Antibody Complex ; Carcinoma, Renal Cell ; Gastrointestinal Stromal Tumors ; Glomerulonephritis ; Humans ; Hypertension ; Indoles ; Protein-Tyrosine Kinases ; Proteinuria ; Pyrroles ; Thrombotic Microangiopathies

It has been well known that dilated cardiomyopathy (D-CMP) has characterized by systolic dysfunction of left ventricle (LV). But there are few studies about LV diastolic and right ventricular (RV) dysfunction in D-CMP. The purpose of this study is to assess the LV and RV systolic function as well as diastolic function in D-CMP. The purpose of this tudy is to assess the LV and RV systolic function as well as diastolic function in D-CMP. The gated blood pool scan (GBPS) was undertaken in 14 patients with D-CMP and 14 normal controls. The results are as follows : 1) Compared to normal controls, the global and regional ejection fraction of LV were significantly reduced (P<0.001) in D-CMP. But, there was no significant difference in LV ejection time between the two groups. 2) Peak filling rate and peak filling time were significantly reduced (P<0.001, P<0.05) in D-CMP 3) Global ejection fraction of RV was also significantly reduced in D-CMP compared to normal controls (P<0.001) But there was no significant difference in ejection rate of right ventricle between the two groups. 4) There was close correlation (R=0.802) between ejection fraction and filling rate of LV : filling rate was also reduced as ejection fraction decreased. And LV filling rate was also reduced with reduction of ejection rate. It is concluded that D-CMP shows diastolic impairment as well as systolic pumping failure and this systolic dysfunction is accounted for the diastolic impairment in D-CMP. And D-CMP shows also right ventricular dysfunction in almost all cases, as well as left ventricular dysfunction.
Cardiomyopathy, Dilated* ; Heart Ventricles ; Humans ; Ventricular Dysfunction, Left ; Ventricular Dysfunction, Right

Actinidia arguta, also called as kiwiberry or hardy kiwifruit, is one of the major varieties of kiwi plants. It is small in size and has no hairs on the surface, which making it easy to be consumed. In addition, it can be cultivated in Asia, due to its cold resistance. We have been interested in the beneficial effects of the fruits of A. arguta and investigated the constituents and biological activities. A new triterpenoid, argutinic acid, along with three triterpenoids and three megastigmines were isolated from the fruits of A. arguta. The structures were determined by spectroscopic analysis including NMR, MS, UV and IR. Among the isolated compounds, two triterpenes, argutinic acid (1) and usrolic acid (4) showed α-glucosidase inhibitory activities.

Actinidia arguta, also called as kiwiberry or hardy kiwifruit, is one of the major varieties of kiwi plants. It is small in size and has no hairs on the surface, which making it easy to be consumed. In addition, it can be cultivated in Asia, due to its cold resistance. We have been interested in the beneficial effects of the fruits of A. arguta and investigated the constituents and biological activities. A new triterpenoid, argutinic acid, along with three triterpenoids and three megastigmines were isolated from the fruits of A. arguta. The structures were determined by spectroscopic analysis including NMR, MS, UV and IR. Among the isolated compounds, two triterpenes, argutinic acid (1) and usrolic acid (4) showed α-glucosidase inhibitory activities.

Actinidia arguta, also called as kiwiberry or hardy kiwifruit, is one of the major varieties of kiwi plants. It is small in size and has no hairs on the surface, which making it easy to be consumed. In addition, it can be cultivated in Asia, due to its cold resistance. We have been interested in the beneficial effects of the fruits of A. arguta and investigated the constituents and biological activities. A new triterpenoid, argutinic acid, along with three triterpenoids and three megastigmines were isolated from the fruits of A. arguta. The structures were determined by spectroscopic analysis including NMR, MS, UV and IR. Among the isolated compounds, two triterpenes, argutinic acid (1) and usrolic acid (4) showed α-glucosidase inhibitory activities.

Actinidia arguta, also called as kiwiberry or hardy kiwifruit, is one of the major varieties of kiwi plants. It is small in size and has no hairs on the surface, which making it easy to be consumed. In addition, it can be cultivated in Asia, due to its cold resistance. We have been interested in the beneficial effects of the fruits of A. arguta and investigated the constituents and biological activities. A new triterpenoid, argutinic acid, along with three triterpenoids and three megastigmines were isolated from the fruits of A. arguta. The structures were determined by spectroscopic analysis including NMR, MS, UV and IR. Among the isolated compounds, two triterpenes, argutinic acid (1) and usrolic acid (4) showed α-glucosidase inhibitory activities.

This is a retrospecitve analysis of 54 patients with stage I or II Non-odgkin's lymphoma involving the head and neck region treated with curative radiotherapy in the Department of Therapeutic Radiology, Seoul National University Hospital during the period of February 1979 through September 1982. The minimum follow-p period was 24 months. The review of histologic slides was available in 36 cases. Waldeyer's ring was the most common extranodal sites (46%). 41% of patients were in the stage I and 59% in the stage II by Ann Arbor classification. Of the 44 patients who responded after radiotherapy, 24 patients (54.5%) subsequently relapsed. Regional recurrence rate was 29%, distant metastasis was 54% and simultaneous regional recurrence and distant metastasis was 17%. The survival rate and disease free survival at 2 years were 57% and 45% respectively. Those patients with a large primary lesion (over 6cm in diameter), multiple conglomerated. extranodal site and diffuse cell type, experienced a high rate of distant metastasis. Therefore it seems desirable to study the use of adjuvant chemotherapy in those patients with a high probability of distant metastasis.
Chemotherapy, Adjuvant ; Classification ; Disease-Free Survival ; Head* ; Humans ; Lymphoma* ; Neck ; Neoplasm Metastasis ; Radiation Oncology ; Radiotherapy* ; Recurrence ; Seoul ; Survival Rate