OBJECTIVETo identify the free radical scavenging activity of ethanolic extract of Evolvulus alsinoides.

METHODSThe free radical scavenging activity was evaluated by in vitro methods like reducing power assay, total antioxidant activity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) reduction, superoxide radical scavenging activity, 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(+)) scavenging activity, hydroxyl radical scavenging assay, and nitric oxide radical scavenging assay, which were studied by using ascorbic acid as standard.

RESULTSThe extract showed significant activities in all antioxidant assays compared with the reference antioxidant ascorbic acid. The total antioxidant activity as well as the reducing power was also found to increase in a dose-dependent manner.

CONCLUSIONEvolvulus alsinoides may act as a chemopreventive agent, providing antioxidant properties and offering effective protection from free radicals.

Antioxidants ; chemistry ; Benzothiazoles ; chemistry ; Biphenyl Compounds ; chemistry ; Convolvulaceae ; chemistry ; Ethanol ; chemistry ; Free Radical Scavengers ; chemistry ; Hydroxyl Radical ; chemistry ; Nitric Oxide ; chemistry ; Oxidation-Reduction ; drug effects ; Picrates ; chemistry ; Plant Extracts ; chemistry ; Sulfonic Acids ; chemistry ; Superoxides ; chemistry