1.Association of ankle-brachial index and pulse wave velocity with stroke in Han, Uighur, and Kazakh population of Xinjiang
Ying-Ying ZHENG ; Yi-Tong MA ; Xiang XIE ; Yi-Ning YANG ; Fen LIU ; Ding HUANG ; Xiao-Mei LI ; Ying HUNG ; Qi TANG ; Bang-Dang CHEN ; Xiang MA ; Lei DU ; Xia GAO ; Ying-Hong WANG ; Baituola GULINAER· ; Zi-Xiang YU
Chinese Journal of Epidemiology 2010;31(11):1255-1258
Objective To investigate the relationship between stroke and ankle-brachial index (ABI), pulse wave velocity (PWV) in Han, Uighur, and Kazakh populations of Xinjiang. Methods Data was from the investigation of cardiovascular risk survey (CRS) program among different nationalities in Xinjiang from October 2007 to March 2010. A total of 14 618 samples aged over 35 with complete data dimension were surveyed. Results ( 1 ) There were 633 patients with stroke, including 258 Hans (4.48%), 247 Uighurs (5.18%), and 128 Kazakhs (3.13%). The incidence of stroke was significant different in the three ethnic groups (P<0.001). (2)Compared to the Han population, the incidence of stroke was higher ( OR= 1.304) in Uighur but lower (OR=0.794) in Kazakh. (3) PWV was significant different between stroke and non-stroke patients. After adjustment for age, body mass index, systolic blood pressure, triglyceride, total cholesterol and other risk factors, the difference remained significant, indicating that PWV (OR=1.001, P<0.001) might associate with the occurrence of stroke. Conclusion The results of this study showed that the incidence of stroke was significantly different in the three ethnic groups. PWV might associate with the occurrence of stroke.
2.Epidemiological survey of carotid artery intima-media thickness in Han, Uygur and Hazakh population of Xinjiang Uygur autonomous region
Yi-Ning YANG ; Wen-Li ZHAO ; Yi-Tong MA ; Xiang XIE ; Fen LIU ; Ding HUANG ; Xiao-Mei LI ; Ying HUANG ; Bang-Dang CHEN ; Xiang MA ; Zhen-Yan FU ; Baituola GULINAER· ; Zi-Xiang YU
Chinese Journal of Cardiology 2011;39(8):755-758
Objective To investigate carotid artery intima-media thickness (IMT) and the correlated risk factors in Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region. Method Cross-sectional and cluster sampling random selected method was carried out for residents over 35 years old in Han, Uygur, Hazakh population of Xinjiang to investigate IMT and correlated risk factors. Results IMT of Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region was (0. 0761 ± 0. 0283 ) cm, (0. 0663 ± 0. 0262) cm, and (0. 0781 ± 0. 0274 ) cm, respectively. There were significantly difference between various nationality( all P <0. 05 ). IMT was thicker in male Han people than in female Han people [(0. 0807 ± 0. 0288 )cm vs. (0. 0717 ± 0. 0270 ) cm, P < 0. 01] and in male Uygur than in female Uygnr residents [(0. 0706 ±0. 0270)cm vs. (0. 0633 ±0. 0252)cm, P <0. 01]and in male Hazakh and female Hazakh residents [(0. 0794 ± 0. 0280) cm vs. (0. 0768 ± 0. 0268 ) cm, P < 0. 01].Linear correlation analysis showed that age ( r = 0. 176, P < 0. 05 ), systolic blood pressure ( r = 0. 168, P < 0. 05 ), diastolic blood pressure ( r = 0. 167, P < 0. 05 ), fasting blood glucose ( r = 0. 053, P < 0. 05 ), total cholesterol(r = 0.097,P < 0.05) and ankle brachial index (r = 0.067, P < 0.05) were significantly correlated with IMT. Conclusions Our results showed that IMT was thicker in Hazakh residents than in Han and Uygnr residents. IMT was closely related to known cardiovascular risk factors including age,systolic blood pressure,diastolic blood pressure,fasting blood glucose, total cholesterol and ankle brachial index level.