1.Relationship between CT Imaging Features and Clinical Pathology of Thyroid Carcinoma
Journal of China Medical University 2017;46(2):165-168
Objective To explore the relationship between CT imaging features and clinical pathology of thyroid carcinoma. Methods The clin-ical data of 42 cases of patients with thyroid carcinoma treated in our hospital from Jaunuary 2014 to October 2015 were analyzed retrospectively. All patients underwent CT imaging before operation. The CT imaging features and surgical pathology results were compared and analyzed ,and the relationship between the two groups was studied. Results CT imaging showed a total of 40 cases of primary lesions,32 cases of uneven density, 30 cases of irregular shape,28 cases of edge blur,19 cases of calcification,25 cases of tumor invasion of the surrounding organs,and the surgical pathology results showed a total of 18 cases of papillary carcinoma,15 cases of undifferentiated carcinoma,6 cases of follicular carcinoma,3 cases of medullary carcinoma,22 cases of tumor invasion of the surrounding organs. The accuracy of CT imaging was 88.10%-95.24%,and the sensitivi-ty was 75.00%-93.75%,and the specificity was 91.30%-100.00%. Conclusion The CT imaging features of thyroid carcinoma and its clinical pa-thology are related. CT has high accuracy ,sensitivity and specificity in the invasive examination of tissue structure ,which is worthy of clinical appli-cation.
2.Simultaneous Determination of Five Saponins in Yao-Bi-Tong Capsules by QAMS
Baidong DAI ; Liqiong SUN ; Yanjing LI ; Gang DING ; Xin LI ; Zhenzhong WANG ; Yuan BI ; Wei XIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(10):2227-2232
This study was aimed to establish a quality evaluation method, quantitative analysis of multi-components with a single-marker (QAMS) to determine the contents of five saponins in Yao-Bi-Tong (YBT) capsules. Ginseno-side Rg1 was used as the internal standard; the relative correction factor (RCF) of notoginsenoside R1, ginsenoside Re, ginsenoside Rb1 and ginsenoside Rd were calculated and evaluated. The contents of 5 saponins were determined by the external standard method and QAMS, respectively. Rationality, feasibility and repeatability of the QAMS method were verified by comparing the results obtained from two different methods. The results showed that RCFs of notoginsenoside R1, ginsenoside Re and ginsenoside Rb1 to ginsenoside Rg1 against YBT capsules were 0.999, 1.228, 0.990 and 1.094, respectively, indicating good reproducibility. These results of two methods had no significant dif-ference. It was concluded that the QAMS method can be accurately, rapidly and reasonably used as a new quality assessment model for ginsenosides in YBT capsules.
3.Application of Three-dimensional Computed Tomography Angiography in the Diagnosis of Cervical Spondylosis with Vertebral Artery Involvement
Journal of China Medical University 2017;46(10):931-933
Objective To explore the use of three-dimensional computed tomography angiography (3D CTA) in the diagnosis of cervical spondylosis with vertebral artery involvement.Methods The study group included 45 patients treated for cervical spondylosis with vertebral artery involvement,from January 2014 to July 2015;42 healthy volunteers were selected as the control group.3D CTA data of all research subjects were evaluated.Results The findings in the experimental group included 3 patients with normal vertebral artery,8 with unilateral narrowed lumen,2 with aberrant route,3 with vascular sclerosis,8 with local lumen stenosis,3 with left side compression,4 with right side compression,and 5 with vessel tortuosity.The right vertebral artery transverse diameter and radius,the left vertebral artery transverse diameter and radius,and 3D images of the left vertebral artery diameter,right transverse diameter,right radius,and left transverse process inner diameter showed statistically significant differences between the two groups (P < 0.05).Conclusion 3D CTA can be used for accurate diagnosis of cervical spondylosis with vertebral artery involvement and can clearly display the diameter of the vertebral artery and the transverse diameter of the vertebral artery.